Ankita Pardiwala, Meghal A Desai, Ritambhara Jangir
{"title":"Polyoxometalate-supported Transition Metal Complexes for Oxidative Cross-Coupling of Amines and Alcohols","authors":"Ankita Pardiwala, Meghal A Desai, Ritambhara Jangir","doi":"10.1039/d4dt02289k","DOIUrl":null,"url":null,"abstract":"Three new hybrid polyoxometalates (POMs) based on transition metals like copper metal with γ-[Mo8O26]4- polyoxometalates, [Cu(DMF)4(Mo8O26)⸱2C3H8NO]⸱1.8 DMF (1), cobalt and nickel metals with hexamolybdate [Co(DMSO)6][Mo6O19] (2), [Ni(DMSO)6][Mo6O19] (3) have been developed. These materials have been characterised by both analytical and spectroscopic techniques (IR, TGA, and CHNO elemental analysis), and structural elucidation has been done using single crystal X-ray diffraction studies. Among these hybrid POMs, the octamolybdate with copper has been used for catalytic production of benzimidazoles. The incorporation of the [Cu(DMF)4] between two octamolybdates results in transformation of POM into useful catalyst, which effectively catalyses the oxidative cross-coupling of anilines, benzyl alcohol, and sodium azide to produce benzimidazole. This catalytic reaction takes place in the presence of tert-Butyl Hydroperoxide (TBHP) at moderate temperature. Benzimidazole and its derivatives are highly preferred due to their wide-ranging biological activities and clinical applications. These compounds are exceptionally effective in terms of both their selectivity ratio and inhibitory activity. The catalytic reaction presented here, is a one-pot component procedure that includes a series of reactions like C-H functionalization, condensation, ortho selective amination, and cyclization.","PeriodicalId":71,"journal":{"name":"Dalton Transactions","volume":null,"pages":null},"PeriodicalIF":3.5000,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dalton Transactions","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4dt02289k","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
引用次数: 0
Abstract
Three new hybrid polyoxometalates (POMs) based on transition metals like copper metal with γ-[Mo8O26]4- polyoxometalates, [Cu(DMF)4(Mo8O26)⸱2C3H8NO]⸱1.8 DMF (1), cobalt and nickel metals with hexamolybdate [Co(DMSO)6][Mo6O19] (2), [Ni(DMSO)6][Mo6O19] (3) have been developed. These materials have been characterised by both analytical and spectroscopic techniques (IR, TGA, and CHNO elemental analysis), and structural elucidation has been done using single crystal X-ray diffraction studies. Among these hybrid POMs, the octamolybdate with copper has been used for catalytic production of benzimidazoles. The incorporation of the [Cu(DMF)4] between two octamolybdates results in transformation of POM into useful catalyst, which effectively catalyses the oxidative cross-coupling of anilines, benzyl alcohol, and sodium azide to produce benzimidazole. This catalytic reaction takes place in the presence of tert-Butyl Hydroperoxide (TBHP) at moderate temperature. Benzimidazole and its derivatives are highly preferred due to their wide-ranging biological activities and clinical applications. These compounds are exceptionally effective in terms of both their selectivity ratio and inhibitory activity. The catalytic reaction presented here, is a one-pot component procedure that includes a series of reactions like C-H functionalization, condensation, ortho selective amination, and cyclization.
期刊介绍:
Dalton Transactions is a journal for all areas of inorganic chemistry, which encompasses the organometallic, bioinorganic and materials chemistry of the elements, with applications including synthesis, catalysis, energy conversion/storage, electrical devices and medicine. Dalton Transactions welcomes high-quality, original submissions in all of these areas and more, where the advancement of knowledge in inorganic chemistry is significant.