Characterization and comparison of metabolites in colostrum from yaks, buffaloes, and cows based on UPLC-QTRAP-MS metabolomics

IF 5.4 2区医学 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Biomaterials Science & Engineering Pub Date : 2024-09-17 DOI:10.1016/j.foodchem.2024.141345

Xueyan Zhang , Changhui Li , Jiaxiang Huang , Qingkun Zeng , Ling Li , Pan Yang , Pengjie Wang , Min Chu , Jie Luo , Hao Zhang

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Abstract

Colostrum from yaks and buffaloes possesses substantial nutritional value, yet the complete array of metabolites within remains insufficiently elucidated. This study scrutinizes the metabolite profiles of yak, buffalo, and cow colostrum utilizing targeted metabolomics paired with ultra-performance liquid chromatography-tandem triple quadrupole linear ion trap mass spectrometry (UPLC-QTRAP-MS). The analysis detected 362 metabolites across all samples. Furthermore, 63, 77, and 46 differential metabolites were selected between yak and buffalo colostrum, yak and cow colostrum, and buffalo and cow colostrum, respectively. Yak colostrum notably contained higher concentrations of inositol, glycine, and carnitine, whereas buffalo colostrum was distinguished by a substantial presence of primary bile acids, which facilitate fat digestion. These findings offer profound insights into yak and buffalo colostrum, providing critical data to propel advancements in the dairy industry.

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基于 UPLC-QTRAP-MS 代谢组学对牦牛、水牛和奶牛初乳中代谢物的表征和比较。

牦牛和水牛的初乳具有很高的营养价值，但其中的各种代谢物仍未得到充分阐明。本研究利用靶向代谢组学和超高效液相色谱-串联三重四极杆线性离子阱质谱（UPLC-QTRAP-MS），仔细研究了牦牛、水牛和奶牛初乳的代谢物特征。分析在所有样本中检测到了 362 种代谢物。此外，在牦牛和水牛初乳、牦牛和奶牛初乳以及水牛和奶牛初乳之间分别筛选出 63、77 和 46 种不同的代谢物。牦牛初乳明显含有较高浓度的肌醇、甘氨酸和肉碱，而水牛初乳则因含有大量促进脂肪消化的初级胆汁酸而与众不同。这些研究结果提供了对牦牛和水牛初乳的深刻见解，为推动乳制品行业的发展提供了关键数据。

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来源期刊

ACS Biomaterials Science & Engineering Materials Science-Biomaterials

CiteScore

10.30

自引率

3.40%

发文量

413

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