Prevalence of Hemophilia and Clinicodemographic Characteristics of Hemophilic Patients Aged ≤ 18 Years in Thi-Qar, Iraq.

IF 1.4 Q3 PEDIATRICS Global Pediatric Health Pub Date : 2024-09-13 eCollection Date: 2024-01-01 DOI:10.1177/2333794X241280119

Ghada Mansoor Abood, Raid Kareem Dehiol, Hayfaa Mohammed Mones

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Abstract

Objectives. This study aims to determine the prevalence of hemophilia in Thi-Qar, Iraq and study clinical and demographic characteristics of patients with hemophilia. Methods. In this cross-sectional study, data were obtained by reviewing all patient medical records and interviewed with the patients and their parents in 2022. The total number of patients enrolled for this study was 110 children. Results. The prevalence of hemophilia in Thi-Qar was 9.5/100 000 population (18.7/100 000 males). Factor VIII inhibitors were positive in 13.1% of patients with hemophilia A (HA). Target joints were developed among 41.4% and 27.3% of patients with HA and hemophilia B, respectively. Hepatitis C virus was positive in 3% of those with HA. Inhibitors development and arthropathy were more among those with severe disease (22% and 46.3%, respectively). Conclusion. Hemophilia prevalence in Thi-Qar was higher than the total prevalence in Iraq reported by World Federation of Hemophilia in 2022.

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伊拉克 Thi-Qar 18 岁以下血友病患者的血友病患病率和临床人口学特征。

研究目的本研究旨在确定伊拉克 Thi-Qar 地区血友病的发病率，并研究血友病患者的临床和人口特征。研究方法。在这项横断面研究中，我们查阅了所有患者的医疗记录，并于 2022 年对患者及其父母进行了访谈，从而获得了相关数据。参加本次研究的患者共有 110 名儿童。研究结果在 Thi-Qar 地区，血友病的发病率为 9.5/100000（男性为 18.7/100000）。13.1%的 A 型血友病（HA）患者体内的因子 VIII 抑制剂呈阳性。分别有 41.4% 和 27.3% 的血友病 A 和血友病 B 患者出现目标关节。3% 的 HA 患者丙型肝炎病毒呈阳性。病情严重的患者中出现抑制剂和关节病的比例更高（分别为 22% 和 46.3%）。结论Thi-Qar 的血友病发病率高于世界血友病联合会 2022 年报告的伊拉克总发病率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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