A comparative study of fennel and dimethicone capsule effects on flatulence rate after cesarean section: A double-blind randomized controlled trial.

IF 1.4 Q3 EDUCATION, SCIENTIFIC DISCIPLINES Journal of Education and Health Promotion Pub Date : 2024-07-29 eCollection Date: 2024-01-01 DOI:10.4103/jehp.jehp_389_23
Marzieh Shahbandari Jourshari, Parvaneh Rezasoltani, Mojgan Nazari, Saman Maroufizadeh, Soudabeh Kazemi Aski, Roja Qobadighadikolaei, Fatemeh Yousefbeyk
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Abstract

Background: Flatulence is one of the gastrointestinal complaints after a cesarean section (C-section). A host of treatments have been used to reduce this symptom in hospitals, and most of them are based on chemical drugs. It is considered that herbal drugs may have fewer side effects than chemical drugs, and it seems that fennel can reduce flatulence through stimulation of bowel movements. This study compared the efficacy of fennel and dimethicone capsules on the flatulence rate in post-cesarean birth women.

Materials and methods: This study was a parallel double-blind randomized controlled trial, conducted in a teaching hospital. Eligible women who underwent a C-section and had the sensation of flatulence were randomly block allocated to the fennel and dimethicone groups (1:1). Each group received drugs every 6 hours for four doses after restarting oral feeding. Flatulence rate was the main variable measured before and one hour after taking each dose by the visual analog scale (VAS). Data were analyzed by statistical tests including repeated-measures analysis of covariance (ANCOVA) based on the intention-to-treat method in Statistical Package for the Social Sciences (SPSS) version 16.0.

Results: The dimethicone group showed a significant reduction in flatulence (F (7,245) =198.5, P < 0.001, η2 p = 0.850). The same trend was also obtained for the fennel group (F (7,266) =215.0, P < 0.001, η2 p = 0.849). However, there was no difference between groups on the flatulence level after adjusting for the baseline level of flatulence (F (1,72) =0.27, P = 0.607, η2 p = 0.004). The same result was also obtained one hour after taking capsule 4 (F (1,72) =0.63, P = 0.430, η2 p = 0.009).

Conclusion: Both fennel and dimethicone capsules can reduce flatulence rate after C-section, although there was no significant difference among them.

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茴香和二甲基硅氧烷胶囊对剖腹产后胀气率影响的比较研究:双盲随机对照试验。
背景:胀气是剖腹产(C-section)后的胃肠道症状之一。医院采用了许多治疗方法来减轻这一症状,其中大多数都是基于化学药物。人们认为草药的副作用可能比化学药物小,而茴香似乎可以通过刺激肠道蠕动来减少胀气。本研究比较了茴香和二甲双胍胶囊对剖宫产后妇女胀气率的疗效:本研究是一项平行双盲随机对照试验,在一家教学医院进行。将符合条件的剖腹产产妇随机分配到茴香组和二甲双胍组(1:1)。每组在重新开始口服喂养后,每 6 小时服用一次药物,共服用四次。胀气率是每次服药前和服药后一小时用视觉模拟量表(VAS)测量的主要变量。数据通过社会科学统计软件包(SPSS)16.0 版的统计检验进行分析,包括基于意向治疗法的重复测量协方差分析(ANCOVA):二甲基硅氧烷组胀气明显减少(F (7,245) =198.5,P < 0.001,η2 p = 0.850)。茴香组也有同样的趋势(F (7,266) =215.0,P < 0.001,η2 p = 0.849)。然而,在对胀气的基线水平进行调整后,各组之间的胀气水平没有差异(F (1,72) =0.27,P = 0.607,η2 p = 0.004)。服用胶囊 4 一小时后也得到了同样的结果(F (1,72) =0.63,P =0.430,η2 p =0.009):结论:茴香胶囊和二甲基硅氧烷胶囊都能降低剖腹产后的胀气率,但两者之间没有显著差异。
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来源期刊
CiteScore
2.60
自引率
21.40%
发文量
218
审稿时长
34 weeks
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