Impact of different intravenous bolus rates on fluid and electrolyte balance and mortality in critically ill patients.

Mutaz I Othman, Emad M Mustafa, Moayad Alfayoumi, Mohamad Y Khatib, Abdulqadir J Nashwan
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Abstract

The effect of intravenous bolus rates on patient outcomes is a complex and crucial aspect of critical care. Fluid challenges are commonly used in critically ill patients to manage their hemodynamic status, but there is limited information available on the specifics of when, how much, and at what rate fluids should be administered during these challenges. The aim of this review is to thoroughly examine the relationship between intravenous bolus rates, fluid-electrolyte balance, and mortality and to analyze key research findings and methodologies to understand these complex dynamics better. Fluid challenges are commonly employed in managing hemodynamic status in this population, yet there is limited information on the optimal timing, volume, and rate of fluid administration. Utilizing a narrative review approach, the analysis identified nine relevant studies that investigate these variables. The findings underscore the importance of a precise and individualized approach in clinical settings, highlighting the need to tailor intravenous bolus rates to each patient's specific needs to maximize outcomes. This review provides valuable insights that can inform and optimize clinical practices in critical care, emphasizing the necessity of meticulous and exact strategies in fluid administration.

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不同的静脉注射速度对重症患者体液和电解质平衡以及死亡率的影响。
静脉注射速度对患者预后的影响是危重症护理中一个复杂而关键的方面。液体挑战常用于危重症患者,以管理其血液动力学状态,但关于在这些挑战中何时、输入多少液体以及以何种速度输入液体的具体信息却很有限。本综述旨在深入研究静脉注射速度、液电平衡和死亡率之间的关系,并分析主要研究成果和方法,以便更好地了解这些复杂的动态变化。输液挑战通常用于控制这类人群的血流动力学状态,但关于最佳输液时机、输液量和输液速度的信息却很有限。本分析采用叙述性综述的方法,确定了九项调查这些变量的相关研究。研究结果强调了在临床环境中采用精确和个体化方法的重要性,突出了根据每位患者的具体需求调整静脉注射速度的必要性,以最大限度地提高疗效。这篇综述提供了宝贵的见解,可以为重症监护临床实践提供信息并优化临床实践,强调了在输液过程中采取细致精确策略的必要性。
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