A Current Perspective on the Effects of Flavonoids in the Treatment of Acne.

Shikha Yadav, Pratichi Singh, Javed Khan, Swetanshu Singh
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Abstract

Pimples, blackheads, whiteheads, etc., are common types of acne that pop up on the skin each time, whenever dead cells and oils obstruct the outgrowth of hair from the hair follicle. It is very common to observe this condition in teenagers, but regardless of age, if the causing condition is met, acne can occur at any point in life. The characteristic feature of all types of acne is it starts with inflammation of the skin. These inflammatory marks (like black spots, pores, small scars, etc.) leave behind even when acne disappears. Plants like vegetables and flowers are naturally rich in different types of polyphenolic compounds called flavonoids. These flavonoids have various key functions, from guiding cell movement to maintaining oxidative pressure in the body. In this study, we discuss six types of flavonoids that have the potential to be used as med-icine for the treatment of different kinds of skin breakouts. Moreover, the result of molecular docking of different proteins that have an association with acne is also discussed.

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黄酮类化合物治疗痤疮效果的当前视角。
粉刺、黑头粉刺、白头粉刺等都是常见的痤疮类型,每当死细胞和油脂阻碍毛囊中毛发的生长时,皮肤上就会冒出这些粉刺。这种情况在青少年身上很常见,但无论年龄大小,只要符合致病条件,痤疮在人生的任何阶段都可能出现。所有类型的痤疮都有一个特点,那就是一开始皮肤就会发炎。这些炎症痕迹(如黑点、毛孔、小疤痕等)即使在痤疮消失后也会留下。蔬菜和花卉等植物天然富含不同类型的多酚化合物,即类黄酮。这些类黄酮具有各种关键功能,从引导细胞运动到维持体内氧化压力。在这项研究中,我们讨论了六种有可能被用作治疗各种皮肤问题的药物的类黄酮。此外,还讨论了与痤疮有关的不同蛋白质的分子对接结果。
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