{"title":"Phytocompound profiling and GC-MS analysis of Lantana camara leaf extract","authors":"","doi":"10.1016/j.jics.2024.101379","DOIUrl":null,"url":null,"abstract":"<div><div>The primary objective of this investigation was to conduct an initial analysis of the chemical composition of <em>Lantana camara</em> leaves, with a specific focus on identifying potential pharmacologically active compounds. Gas chromatography-mass spectrometry (GC-MS) was employed to perform a preliminary phytochemical screening on various leaf extracts. The results identified multiple classes of phytoconstituents in <em>Lantana camara</em> leaves, including steroids, terpenoids, flavonoids, quinones, carbohydrates, alkaloids, and phenols. A detailed analysis of the crude aqueous extract using GC-MS identified several biologically active components, such as 13-docosenamide, alpha-hydroxyisocaproic acid, cyclo(L-prolyl-L-valine), and 2,5-piperazinedione etc. These compounds were present in varying proportions, indicating a complex chemical composition within the leaves of <em>Lantana camara</em>. The study's findings suggest that these identified chemicals may contribute to the plant's pharmacological properties and hold significant potential for innovative medical applications. The plant's bioactive compounds, including pyrrolo[1,2-a]pyrazine-1,4-dione, hexadecanoic acid, hexahydro and oleic acid, point to a wide range of possible therapeutic benefits. This investigation provides valuable insights into the chemical constituents of <em>Lantana camara</em> and underscores the potential significance of these compounds in medicinal research. Furthermore, it opens up promising avenues for future studies and the exploration of new pharmaceutical opportunities.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2000,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Indian Chemical Society","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0019452224002590","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The primary objective of this investigation was to conduct an initial analysis of the chemical composition of Lantana camara leaves, with a specific focus on identifying potential pharmacologically active compounds. Gas chromatography-mass spectrometry (GC-MS) was employed to perform a preliminary phytochemical screening on various leaf extracts. The results identified multiple classes of phytoconstituents in Lantana camara leaves, including steroids, terpenoids, flavonoids, quinones, carbohydrates, alkaloids, and phenols. A detailed analysis of the crude aqueous extract using GC-MS identified several biologically active components, such as 13-docosenamide, alpha-hydroxyisocaproic acid, cyclo(L-prolyl-L-valine), and 2,5-piperazinedione etc. These compounds were present in varying proportions, indicating a complex chemical composition within the leaves of Lantana camara. The study's findings suggest that these identified chemicals may contribute to the plant's pharmacological properties and hold significant potential for innovative medical applications. The plant's bioactive compounds, including pyrrolo[1,2-a]pyrazine-1,4-dione, hexadecanoic acid, hexahydro and oleic acid, point to a wide range of possible therapeutic benefits. This investigation provides valuable insights into the chemical constituents of Lantana camara and underscores the potential significance of these compounds in medicinal research. Furthermore, it opens up promising avenues for future studies and the exploration of new pharmaceutical opportunities.
期刊介绍:
The Journal of the Indian Chemical Society publishes original, fundamental, theorical, experimental research work of highest quality in all areas of chemistry, biochemistry, medicinal chemistry, electrochemistry, agrochemistry, chemical engineering and technology, food chemistry, environmental chemistry, etc.