Journal of the Indian Chemical Society最新文献

{"title":"Synthesis of a novel 7-chloroquinoline-sulphocoumarin hybrid: Characterization, ADME profiling and elucidation of its antiproliferative and anti-EMT potential","authors":"Garima Chand ,&nbsp;Deepa Kholia ,&nbsp;Amrita Kumari ,&nbsp;Ankita H. Tripathi ,&nbsp;Santosh K. Upadhyay ,&nbsp;Penny Joshi","doi":"10.1016/j.jics.2024.101470","DOIUrl":"10.1016/j.jics.2024.101470","url":null,"abstract":"<div><div>In the present study, the annulation of 4,7-dichloroquinoline and sulphocoumarin led to the efficient synthesis of a novel hybrid molecule. Both 4,7-dichloroquinoline and sulphocoumarin are significant due to their distinct pharmacological properties. Quinoline derivatives, such as 4,7-dichloroquinoline, are well-known for their broad spectrum of biological activities, including antimalarial, antibacterial, and anticancer properties. Sulphocoumarin compounds, on the other hand, have been recognised for their enzyme inhibition and antioxidant activities, which contribute to their therapeutic potential. By combining these two pharmacophores, we aimed to harness and enhance their individual therapeutic effects. The synthesized compound <strong>8</strong> was characterised by FT-IR, NMR (¹H and ¹³C), and mass spectrometry. Additionally, the physicochemical properties of the compound were evaluated through in silico pharmacokinetic analysis. The compound showed notable antiproliferative potential against MCF-7 human breast cancer cells (IC₅₀ = 27.53 ± 0.02 μg/mL). Besides, it reduced MCF-7 cell motility in a concentration-dependent manner. Furthermore, the effect of the hybrid compound on the epithelial-mesenchymal transition (EMT) was evaluated by its ability to modulate MCF-7 cell motility, as well as the expression of major mesenchymal marker genes, such as <em>Vim</em>, <em>Zeb1</em>, <em>Snail</em>, <em>Slug</em>, and <em>TGF-β</em>. The dual action of our synthesized hybrid compound <strong>8</strong> as an anti-proliferative and anti-EMT agent suggests its further characterization in the <em>in vivo</em> models and elucidation of any synergistic activity in combination with established anti-cancer agents.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"101 12","pages":"Article 101470"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142746129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation, characterization, and study of radiation shielding performance of YBa2Cu3Oy/WO3 ceramics exposed to different gamma rays doses","authors":"Y. Slimani ,&nbsp;M.H.A. Mhareb ,&nbsp;M. Kh Hamad ,&nbsp;I. Alrammah ,&nbsp;A. Thakur","doi":"10.1016/j.jics.2024.101479","DOIUrl":"10.1016/j.jics.2024.101479","url":null,"abstract":"<div><div>The need for shielding materials amplified gradually due to the usage of ionizing radiation in our lives. The current work studied the impact of different doses of gamma rays on the radiation shielding, optical, and structural properties of the YBCO/WO₃ sample. The lattice parameters showed a slight variation when YBCO/WO₃ products were exposed to different doses of gamma rays. The density slightly decreased from 6.377 for 0 kGy to 6.369 g/cm³ for 50 kGy. The variation in radiation shielding properties was assessed before and after irradiation based on linear attenuation coefficient (LAC). A slight variation was noted in LAC, so the other parameters were calculated for the non-irradiated sample. According to the results, it might be said that YBCO/WO₃ product showed a high stability against gamma-rays’ doses, which can be nominated for exploitation in radiation shielding fields.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"101 12","pages":"Article 101479"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142746130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on indole CB2 ligands based on 3D-QSAR, molecular docking and molecular dynamics simulation","authors":"Jiaojiao Li ,&nbsp;Jiacheng Shen ,&nbsp;Xinxin Li ,&nbsp;Zheng Qin ,&nbsp;Zheng Jiang ,&nbsp;Shengxin Sun ,&nbsp;Zhengfu Li","doi":"10.1016/j.jics.2024.101478","DOIUrl":"10.1016/j.jics.2024.101478","url":null,"abstract":"<div><div>Cannabinoid receptor type 2 (CB2) is a very promising therapeutic target for a variety of potential indications, such as cancer, inflammation, immune regulation and so on. However, no CB2-targeting drug has been approved to date. Therefore, it would be beneficial to explore new CB2 ligands. A 3D-QSAR study for CB2 receptor ligands were developed based on CoMFA and CoMSIA models, using 21 CB2 agonists previously reported by our laboratory. The results indicate that both CoMFA (N = 4, <em>q</em>² = 0.645, <em>r</em>² = 0.984) and CoMSIA (N = 6, <em>q</em>² = 0.516, <em>r</em>² = 0.970) have good predictive ability and stability. Contour maps of the CoMFA and CoMSIA models provide the relationship between steric effects, electrostatic effects, etc. and enhanced CB2 ligand activity. This information was used to design 1240 structurally novel compounds. The activity prediction, pharmacophore screening, molecular docking and ADME/T prediction of the designed molecules were performed in turn, and the final compound <strong>AL18</strong> was hit. <strong>AL18</strong> was evaluated for stability studies by molecular dynamics simulation studies. <strong>AL18</strong> showed better stability than reference standards (<strong>GW405833</strong>, compound <strong>2</strong>) in studied parameters such as RMSD, RMSF, Rg, etc. The binding free energy based on MM/PBSA of <strong>AL18</strong> is −35.191 kcal mol⁻¹, indicating strong binding interactions. <strong>AL18</strong> can be explored as a lead compound for early research, which has not yet been experimentally explored. This study also provides a strong theoretical foundation for the subsequent design and development of indole CB2 ligands.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"101 12","pages":"Article 101478"},"PeriodicalIF":3.2,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Linum usitatisimum mucilage synergistic amalgamation of metal oxide electrodes for super-capacitive applications","authors":"Uruwah I. Courage ,&nbsp;Nawal Alghamdi ,&nbsp;Imosobomeh L. Ikhioya ,&nbsp;Faith U. Ochai-Ejeh ,&nbsp;Samson O. Aisida ,&nbsp;Assumpta C. Nwanya ,&nbsp;Paulinus E. Ugwoke ,&nbsp;Fabian I. Ezema","doi":"10.1016/j.jics.2024.101477","DOIUrl":"10.1016/j.jics.2024.101477","url":null,"abstract":"<div><div>The study's focus is on developing and evaluating Linum usitatissimum mucilage-based nanoparticles integrated into the metal oxide electrode for super-capacitive applications. The energy bandgap of the electrode is L.U-2.741 eV, FeO₄-2.177 eV, CoO₄-2.082 eV, and FeCo₂O₄-1.586 eV. The calculated crystallite sizes for the materials are Fe₃O₄-L.U (11.77 nm), Co₃O₄-L.U (18.01) and FeCo₂O₄-L.U (16.67). The micrograph of the material shows a cluster-like structure formed by the agglomeration of linum usitatisimum. The absorption peak was prominent at 219 nm and to gradually decrease at about 317 nm. If the absorbance decreases with wavelength. The potential windows (−0.4 to 0.3 V for L.U, Fe₃O₄-L.U, and Co₃O₄-L.U, and −0.6 to 0.1 V for FeCoO₃) displayed prominent peaks in electrode reduction/oxidation, showing strong pseudo-capacitive performance. The estimated specific capacitances for L.U are 6.74, 3.18, 1.82 and 1.16 F/g. For Fe₃O₄-L.U the specific capacitances are 16.9, 11.1, 7.11 and 3.75 F/g while for that of Co₃O₄-L.U are 21.7, 12.2, 7.68 and 3.98 F/g. The estimated specific capacitances for FeCo₂O₄-L.U are 10.2, 6.46, 3.95 and 2.00 F/g. The GCD plot of Linum Usitatissimum and FeCoO₃-L.U shows coulombic efficiency of 92 % and 97 %, respectively, showing their suitability for supercapacitor applications.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"101 12","pages":"Article 101477"},"PeriodicalIF":3.2,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of metallic surfactants from Jatropha oil and study of it's molecular structure and antimicrobial activity on plant pathogen Xanthomonas campestris","authors":"Juzer Ali Rangwala,&nbsp;Dr Geetha Sarasan","doi":"10.1016/j.jics.2024.101472","DOIUrl":"10.1016/j.jics.2024.101472","url":null,"abstract":"<div><div>Jatropha Oil is non edible and it has several medicinal properties,on saponification with concentrated alkali like NaOH and KOH, valuable water soluble surfactants can be derived which serves for cleansing purpose. In present study chemical constituents present in Jatropha oil taken as raw material has been characterized by GC-MS (FAME) method. Physico-chemical properties such as Saponification value, Iodine value, Free Fatty acid value etc. were determined as per standard titrimetric methods which ascertains the purity of oil. Sodium, Potassium surfactant of Jatropha oil has been synthesized by reacting Jatropha oil with alkaline lye in aqueous medium. Transition metal (Copper and Nickel) based surfactants were derived by metathesis with sodium soap and molecular structure of the synthesized surfactant was determined by FTIR method. The antimicrobial activity of all surfactants was studied on plant pathogen <em>Xanthomonas campestris.</em> These surfactants exhibit prominent antimicrobial activity in the range of 5000 ppm–10000 ppm. Water soluble Jatropha surfactants are biodegradable in nature and hence they could prove to be an effective alternate to other conventional antibacterial agents that persist in the environment and cause the problem of bio-accumulation.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"101 12","pages":"Article 101472"},"PeriodicalIF":3.2,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A potent moiety of (E)-5-(4-(5-chlorothiophene-2-carbonyl) piperazin-1-yl)-N'-(substituted methylene) benzofuran-2-carbohydrazide: Molecular docking, synthesis and antimicrobial evaluation","authors":"Hirenkumar Lad ,&nbsp;Karan Joshi ,&nbsp;Divyesh Joshi ,&nbsp;Mayank Patel ,&nbsp;Nomeshvar Yadav","doi":"10.1016/j.jics.2024.101474","DOIUrl":"10.1016/j.jics.2024.101474","url":null,"abstract":"<div><div>In this paper, we report new hybrid molecules of (<em>E)</em>-5-(4-(5-chlorothiophene-2-carbonyl) piperazin-1-yl)-<em>N'</em>-(substituted methylene) benzofuran-2-carbohydrazide <strong>(10a-10r)</strong> as an anti-microbial agent. The synthesized compounds have been characterized by FT-IR, Mass, ¹H and ¹³C NMR spectroscopic techniques and were evaluated on gram-positive (<em>S. aureus</em> and <em>S. pyogenes</em>), gram-negative (<em>E. coli</em> and <em>P. aeruginosa</em>) bacterial strain and fungal (<em>C. albicans</em> and <em>A. Niger)</em> strains by the broth dilution method. The compounds exhibited significant antibacterial and antifungal activities, out of which compounds <strong>10b</strong> and <strong>10o,</strong> having MIC 62.5 μg/mL, showed the best activity against gram-positive bacterial strain <em>S. aureus.</em> Furthermore, compounds <strong>10e, 10j</strong>, and <strong>10m,</strong> having MIC 62.5 μg/mL, showed the best activity against the gram-negative bacterial strain <em>E. coli</em>. In contrast, compounds <strong>10g</strong> and <strong>10n</strong>, having MIC 62.5 μg/mL, showed the best activity against gram-negative bacterial strain <em>P. aeruginosa</em>. Out of the series, compounds <strong>10h</strong> and <strong>10l</strong> have been found to possess better inhibitory activity with MIC 250 μg/mL<em>,</em> compared to standard drug Griseofulvin (MIC 500 μg/mL) against anti-fungal strain <em>C. albicans</em>. Additionally, the compounds were docked in DNA gyrase enzyme of gram-positive and gram-negative bacteria and also C. <em>albicans</em> fungal. Compounds 10h and 10l were docked with the CYP51 of <em>C. albicans</em> (PDB: 5V5Z), revealing that the benzyl ring of the carbohydrazide Schiff base formed a potent π-π stacking interaction with the Hem601 complex. Additionally, the carbonyl part of the amide functional group connecting the piperazine and thiophene rings was found to interact with His377 through a hydrogen bond, which is considered a significant interaction. The compounds are also checked for their drug-likeness property using Lipinski rule. On the basis of these findings, we can conclude that (<em>E)</em>-5-(4-(5-chlorothiophene-2-carbonyl) piperazin-1-yl)-<em>N'</em>-(substituted methylene) benzofuran-2-carbohydrazide is a potent antimicrobial agent against a variety of bacterial and fungal species.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"101 12","pages":"Article 101474"},"PeriodicalIF":3.2,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of epoxy/flyash composites containing halloysite nanotubes: Mechanical, morphological, and thermal degradation kinetics","authors":"Abrar Ahamad ,&nbsp;Pradeep Kumar ,&nbsp;Brajesh Kumar","doi":"10.1016/j.jics.2024.101476","DOIUrl":"10.1016/j.jics.2024.101476","url":null,"abstract":"<div><div>This research article investigates the development of a composite material by the inclusion of halloysite nanotubes (HNTs) into an epoxy/flyash matrix using a solution blending technique. The HNTs were added at different loadings and were effectively dispersed throughout the epoxy/flyash matrix. The thermal properties and degradation kinetics of the epoxy/flyash composites were studied with a thermogravimetric analyzer (TGA) at different heating speeds (10, 15, 20, and 25 °C/min). TGA measurements showed a considerable improvement in the thermal stability of the composites. Incorporating 3 phr of HNTs into epoxy/flyash composites increased thermal stability by 13 °C, 16 °C, and 18 °C, with weight losses of 5 %, 10 %, and 50 %, respectively, as compared to composites without HNTs. The thermal degradation activation energy (<em>E</em>) was calculated using the model-free Kissinger Akahir-Sunose (KAS) and Flynn-Wall-Ozawa (FWO), and it was revealed that epoxy/flyash composites containing 3 phr HNTs have the highest <em>E,</em> 77.52 and 79.89 kJ/mol, respectively. The SEM micrographs of 3 phr HNTs show uniform dispersion of HNTs onto epoxy/flyash composites, resulting in a tensile strength increase from 37.2 MPa to 43.6 MPa and modulus increase from 1238.4 MPa to 1463.6 MPa. The obtained results show that the addition of flyash and nanofiller (HNTs) to the epoxy matrix greatly increases the mechanical and thermal properties.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"101 12","pages":"Article 101476"},"PeriodicalIF":3.2,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Room-temperature CO2 conversion to carbon using liquid metal alloy catalysts without external energy input","authors":"Mahesh Kumar Gagrai","doi":"10.1016/j.jics.2024.101467","DOIUrl":"10.1016/j.jics.2024.101467","url":null,"abstract":"<div><div>Conversion of CO₂ to carbon using a catalyst typically requires significant energy input such as heat, pressure, or electricity. This is due to its strong bonds and the energy needed to initiate the reaction. The energy requirement for CO₂ conversion may also lead to carbon emissions if sources are fossil-based. There is less exploration at low temperatures and without an external energy CO₂ conversion to solid carbon. Here, we show a liquid metal alloy (In_0.2Ga_0.8) used as a catalyst for converting CO₂ to carbon at room temperature without external energy. The carbon formed was characterized, and the calculated free energy of the reduction reaction was −530 kJ mol⁻¹.The catalyst coated over a ceramic surface observed similar phenomena of CO₂ conversion to carbon at room temperature. The conversion was five times higher at catalyst-coated ceramic membranes than at bulk catalysts. The CO₂ conversion efficiency was 60 % at the catalytic membrane for continuous flow of CO₂ at room temperature. EDX and XPS studies confirmed the formation of carbon at the catalyst surface. Our study may open the topic of membrane-based catalysis of CO₂ for practical carbon conversion at lower operating costs at the industrial scale to achieve net-zero emissions.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"101 12","pages":"Article 101467"},"PeriodicalIF":3.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing therapeutics: A novel mutual prodrug of ketoprofen and Chlorzoxazone for enhanced efficacy and safety","authors":"Ketaki S. Salve ,&nbsp;Neela M. Bhatia ,&nbsp;Sameer J. Nadaf","doi":"10.1016/j.jics.2024.101471","DOIUrl":"10.1016/j.jics.2024.101471","url":null,"abstract":"<div><div>The development of mutual prodrugs signifies a pivotal advancement in the optimization of therapeutic profiles for established pharmaceuticals. This study explores the synthesis and evaluation of an innovative mutual prodrug combining the nonsteroidal anti-inflammatory drug (NSAID) Ketoprofen and the skeletal muscle relaxant Chlorzoxazone. Designed to alleviate gastric irritation inherent to NSAIDs while capitalizing on the synergistic benefits of both agents, the synthesized mutual prodrug was characterized and confirmed through extensive physicochemical and spectroscopic studies. Solubility and partition coefficient analyses indicated heightened lipophilicity, enhancing the prodrug's suitability for oral administration compared to its parent drugs. Additionally, protein binding studies revealed a low binding affinity, suggesting improved bioavailability. Subsequent <em>in vitro</em> hydrolysis studies assessed the prodrug's stability across various pH levels (1.2, 3, 5 and 7.4) simulated gastric and intestinal fluids, plasma and rat liver homogenate, with quantitative evaluation performed by high-performance liquid chromatography. The prodrug remained stable and unhydrolyzed in the stomach after absorption, but underwent rapid cleavage by esterase's in blood and rat liver homogenate, releasing the active parent drugs. Our investigation underscores the transformative potential of mutual prodrug design in optimizing the efficacy and safety profile of combining NSAIDs with muscle relaxants. This approach offers a novel therapeutic strategy that enhances patient outcomes while minimizing adverse effects, paving the way for innovative treatments in managing musculoskeletal conditions and improving overall quality of life.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"101 12","pages":"Article 101471"},"PeriodicalIF":3.2,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation on the structure formation, morphology, electronic and magnetic properties of BaFe12O19 nanopowders synthesized by utilizing sol-gel technique using L-sorbose as a fuel agent","authors":"A. Maria Therese ,&nbsp;S. Jesurani ,&nbsp;Kanagesan Samikannu ,&nbsp;K. Chellemmal ,&nbsp;M. Easwari ,&nbsp;A. Prakasam","doi":"10.1016/j.jics.2024.101475","DOIUrl":"10.1016/j.jics.2024.101475","url":null,"abstract":"<div><div>Hexagonal barium ferrite (BaFe₁₂O₁₉) is a highly magnetic material due to its high resistivity, large permeability and low loss behaviour. It was mainly focused on applications in the electric, magnetic and telecom industries because of their good dielectric properties at microwave frequencies. The brown colored nanoparticles (NPs) of BaFe₁₂O₁₉ were carried out by the sol-gel approach using L-sorbose as a fuel synthesized from the ethylene glycol and oxalic acids. The synthesized nanopowders were characterized by thermal, X-ray diffraction (XRD), scanning electron microscopy (SEM), FT-IR, photoluminescence (PL), ultraviolet visible (UV–Vis), energy dispersive spectroscopy (EDS), cyclic voltammetry (CV) and vibrating sample magnetometer (VSM) techniques. XRD peak indicates the formation of good quality nanocrystalline hexagonal BaFe12O19 phase of the synthesized sample. The FT-IR spectra exhibited the significant vibrational frequencies of BaFe12O19 NPs were detected at 448, 578 and 768 cm⁻¹ for 800 °C, which suggests the formation of a hexagonal phase. The SEM images of BaFe₁₂O₁₉ powders at 800 °C indicated the micro-sized flakes shape with crystallite size ranging from 40 to 65 nm. The EDS was performed to analyze the total energy distributions and elemental individual content of the prepared powders and it was also found that the content of Ba reduced as the content of Fe increased. Further, the physical properties of the synthesized NPs were determined by VSM analyzer and the high saturation magnetization (M_s = 18.41 emu/g), remanence magnetization (M_r = 10.20 emu/g) and magnetization coercive force (H_c = 5707 Oe). Overall, these results suggested the prepared nanoparticles calcined at 800 °C have the good potential for utilization in many applications such as magnetic recording, fast random access memory, electronic devices, etc.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"101 12","pages":"Article 101475"},"PeriodicalIF":3.2,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}