Biomedical applications of terbium oxide nanoparticles by Couroupita guianensis aubl leaves extract: A greener approach

IF 5.45 Q1 Physics and Astronomy Nano-Structures & Nano-Objects Pub Date : 2024-09-25 DOI:10.1016/j.nanoso.2024.101341

P. Senthil Pandi , P. Krishnan , S. Sathish , S. Sudhahar

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Abstract

Couroupita guianensis aubl (CGA) is a plant known for its therapeutic characteristics and extensively used in biomedicine. This paper presents a method for synthesizing terbium oxide (Tb₂O₃) nanoparticles (NPs) utilizing the leaves extract of CGA which is sustainable and environmentally friendly. The practical synthesis of Tb₂O₃ NPs was validated using UV–vis analysis, revealing a prominent peak at 246 nm and the calculated band gap value of 3.02 eV. The existence of numerous functional groups and molecular bonding interactions in the Tb₂O₃ NPs was confirmed using FTIR spectrum analysis. In addition, the XRD examination confirmed that the nanoparticles had a crystalline structure with dimensions of 27.3 nm. The TEM imaging revealed the particle size of around 5.63 nm. The manufactured Tb₂O₃ NPs were analysed for anticancer capabilities against human MCF-7 cancer cell lines. Overall, our study emphasizes the ability of green-produced Tb₂O₃ NPs to be versatile agents with antidiabetic, antioxidant, and anticancer effects. These nanoparticles are potentially used in biomedical applications, providing long-lasting solutions to various health-related problems.

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库鲁皮塔（Couroupita guianensis aubl）叶提取物的氧化铽纳米粒子的生物医学应用：一种更环保的方法

Couroupita guianensis aubl（CGA）是一种以其治疗特性而闻名的植物，被广泛应用于生物医学领域。本文介绍了一种利用 CGA 叶提取物合成氧化铽（Tb2O3）纳米粒子（NPs）的方法，该方法可持续且环保。通过紫外-可见分析验证了 Tb2O3 NPs 的实际合成，结果表明在 246 纳米处有一个突出的峰值，计算得出的带隙值为 3.02 eV。傅立叶变换红外光谱分析证实了 Tb2O3 NPs 中存在大量官能团和分子键相互作用。此外，X 射线衍射（XRD）检查证实，纳米粒子具有晶体结构，尺寸为 27.3 纳米。TEM 成像显示颗粒大小约为 5.63 nm。我们分析了制备的 Tb2O3 NPs 对人类 MCF-7 癌细胞株的抗癌能力。总之，我们的研究强调了绿色制备的 Tb2O3 NPs 可作为具有抗糖尿病、抗氧化和抗癌作用的多功能制剂。这些纳米粒子可用于生物医学应用，为各种健康相关问题提供持久的解决方案。

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来源期刊

Nano-Structures & Nano-Objects Physics and Astronomy-Condensed Matter Physics

CiteScore

9.20

自引率

0.00%

发文量

审稿时长

22 days

期刊介绍： Nano-Structures & Nano-Objects is a new journal devoted to all aspects of the synthesis and the properties of this new flourishing domain. The journal is devoted to novel architectures at the nano-level with an emphasis on new synthesis and characterization methods. The journal is focused on the objects rather than on their applications. However, the research for new applications of original nano-structures & nano-objects in various fields such as nano-electronics, energy conversion, catalysis, drug delivery and nano-medicine is also welcome. The scope of Nano-Structures & Nano-Objects involves: -Metal and alloy nanoparticles with complex nanostructures such as shape control, core-shell and dumbells -Oxide nanoparticles and nanostructures, with complex oxide/metal, oxide/surface and oxide /organic interfaces -Inorganic semi-conducting nanoparticles (quantum dots) with an emphasis on new phases, structures, shapes and complexity -Nanostructures involving molecular inorganic species such as nanoparticles of coordination compounds, molecular magnets, spin transition nanoparticles etc. or organic nano-objects, in particular for molecular electronics -Nanostructured materials such as nano-MOFs and nano-zeolites -Hetero-junctions between molecules and nano-objects, between different nano-objects & nanostructures or between nano-objects & nanostructures and surfaces -Methods of characterization specific of the nano size or adapted for the nano size such as X-ray and neutron scattering, light scattering, NMR, Raman, Plasmonics, near field microscopies, various TEM and SEM techniques, magnetic studies, etc .