{"title":"Age of Information-Based Abnormality Detection With Decay in the Human Circulatory System","authors":"Saswati Pal;Jorge Torres Gómez;Regine Wendt;Stefan Fischer;Falko Dressler","doi":"10.1109/TMBMC.2024.3426951","DOIUrl":null,"url":null,"abstract":"Detecting abnormalities early by deploying a network of mobile nanosensors within the human body remains a challenging task. Current methods for abnormality detection rely on placing gateways at arbitrary locations. Given the critical importance of timely monitoring and detection in severe infections, relying on arbitrary gateway locations introduces delays in detection. In this work, we conducted an analysis of the impact of gateway placement and infection locations on detection time, detection ratio, and the average Peak Age of Information (PAoI). Furthermore, we also added decay of nanosensors similar to operation in the human body. We investigated its implications on both the detection ratio of abnormalities and the average PAoI. We employed a Monte Carlo simulation involving 1000 nanosensors circulating in the HCS for 500 seconds. The results revealed that the favorable gateway position is at the heart, minimizing detection time and enhancing the detection ratio for various infection locations. Furthermore, we observed that the detection ratio exhibited reduced variance with increased decay rates in nanosensors. Analyzing the PAoI across varying decay rates highlighted the importance of nanosensor quantity in relation to decay rate in ensuring accurate and timely infection localization.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/10594753/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
引用次数: 0
Abstract
Detecting abnormalities early by deploying a network of mobile nanosensors within the human body remains a challenging task. Current methods for abnormality detection rely on placing gateways at arbitrary locations. Given the critical importance of timely monitoring and detection in severe infections, relying on arbitrary gateway locations introduces delays in detection. In this work, we conducted an analysis of the impact of gateway placement and infection locations on detection time, detection ratio, and the average Peak Age of Information (PAoI). Furthermore, we also added decay of nanosensors similar to operation in the human body. We investigated its implications on both the detection ratio of abnormalities and the average PAoI. We employed a Monte Carlo simulation involving 1000 nanosensors circulating in the HCS for 500 seconds. The results revealed that the favorable gateway position is at the heart, minimizing detection time and enhancing the detection ratio for various infection locations. Furthermore, we observed that the detection ratio exhibited reduced variance with increased decay rates in nanosensors. Analyzing the PAoI across varying decay rates highlighted the importance of nanosensor quantity in relation to decay rate in ensuring accurate and timely infection localization.
期刊介绍:
As a result of recent advances in MEMS/NEMS and systems biology, as well as the emergence of synthetic bacteria and lab/process-on-a-chip techniques, it is now possible to design chemical “circuits”, custom organisms, micro/nanoscale swarms of devices, and a host of other new systems. This success opens up a new frontier for interdisciplinary communications techniques using chemistry, biology, and other principles that have not been considered in the communications literature. The IEEE Transactions on Molecular, Biological, and Multi-Scale Communications (T-MBMSC) is devoted to the principles, design, and analysis of communication systems that use physics beyond classical electromagnetism. This includes molecular, quantum, and other physical, chemical and biological techniques; as well as new communication techniques at small scales or across multiple scales (e.g., nano to micro to macro; note that strictly nanoscale systems, 1-100 nm, are outside the scope of this journal). Original research articles on one or more of the following topics are within scope: mathematical modeling, information/communication and network theoretic analysis, standardization and industrial applications, and analytical or experimental studies on communication processes or networks in biology. Contributions on related topics may also be considered for publication. Contributions from researchers outside the IEEE’s typical audience are encouraged.