首页 > 最新文献

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications最新文献

英文 中文
Bacterial Chemotaxis in Molecular Communication: Experimental and Simulation Analysis of Receiver Placement and Gradient Dynamics 分子通讯中的细菌趋化性:接收器放置和梯度动力学的实验和模拟分析
IF 2.3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-12 DOI: 10.1109/TMBMC.2026.3652361
Mustafa Ozan Duman;Ibrahim Isik;Esme Isik
Bacteria-based nanonetworks (BNs) represent a promising strategy for nanoscale information transfer, utilizing bacterial motility and chemotaxis for targeted message delivery. This study analyzes BN performance through both experimental validation and a custom-developed three-dimensional (3D) simulation program built in MATLAB, focusing on receiver (RX) placement, chemoattractant release rate ( $Q$ ), and bacterial lifespan. The simulation employs experimentally validated parameters and models bacterial behavior under various spatial configurations. Results demonstrate that RX positioning significantly affects communication efficiency, with asymmetric placement causing uneven chemoattractant gradients and reduced success rates. While higher $Q$ values improve reach time and delivery success, bacterial lifespan becomes a limiting factor at extended distances. Experimental findings using agar-based assays confirm a threshold distance beyond which bacterial motility becomes ineffective. These insights provide practical guidance for optimizing BN systems by balancing signal strength with biological constraints. Future work should explore adaptive bacterial strategies and dynamic environmental conditions to further enhance BN reliability and applicability in areas such as targeted drug delivery and biosensing.
基于细菌的纳米网络(BNs)是一种很有前途的纳米级信息传递策略,利用细菌的运动性和趋化性来靶向信息传递。本研究通过实验验证和在MATLAB中构建的定制三维(3D)仿真程序分析了BN的性能,重点关注接收器(RX)放置,化学引诱剂释放速率($Q$)和细菌寿命。模拟采用实验验证的参数和模拟细菌在不同空间配置下的行为。结果表明,RX定位显著影响通信效率,不对称放置导致化学引诱剂梯度不均匀,成功率降低。虽然较高的Q值提高了到达时间和递送成功率,但细菌寿命成为延长距离的限制因素。实验结果使用琼脂为基础的分析证实了阈值距离,细菌的运动变得无效。这些见解为通过平衡信号强度和生物约束来优化BN系统提供了实际指导。未来的工作应探索适应性细菌策略和动态环境条件,以进一步提高BN在靶向给药和生物传感等领域的可靠性和适用性。
{"title":"Bacterial Chemotaxis in Molecular Communication: Experimental and Simulation Analysis of Receiver Placement and Gradient Dynamics","authors":"Mustafa Ozan Duman;Ibrahim Isik;Esme Isik","doi":"10.1109/TMBMC.2026.3652361","DOIUrl":"https://doi.org/10.1109/TMBMC.2026.3652361","url":null,"abstract":"Bacteria-based nanonetworks (BNs) represent a promising strategy for nanoscale information transfer, utilizing bacterial motility and chemotaxis for targeted message delivery. This study analyzes BN performance through both experimental validation and a custom-developed three-dimensional (3D) simulation program built in MATLAB, focusing on receiver (RX) placement, chemoattractant release rate (<inline-formula> <tex-math>$Q$ </tex-math></inline-formula>), and bacterial lifespan. The simulation employs experimentally validated parameters and models bacterial behavior under various spatial configurations. Results demonstrate that RX positioning significantly affects communication efficiency, with asymmetric placement causing uneven chemoattractant gradients and reduced success rates. While higher <inline-formula> <tex-math>$Q$ </tex-math></inline-formula> values improve reach time and delivery success, bacterial lifespan becomes a limiting factor at extended distances. Experimental findings using agar-based assays confirm a threshold distance beyond which bacterial motility becomes ineffective. These insights provide practical guidance for optimizing BN systems by balancing signal strength with biological constraints. Future work should explore adaptive bacterial strategies and dynamic environmental conditions to further enhance BN reliability and applicability in areas such as targeted drug delivery and biosensing.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"298-308"},"PeriodicalIF":2.3,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146082112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2025 Index IEEE Transactions on Molecular, Biological and Multi-Scale Communications 2025年IEEE分子、生物和多尺度通信学报
IF 2.3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-08 DOI: 10.1109/TMBMC.2026.3651917
{"title":"2025 Index IEEE Transactions on Molecular, Biological and Multi-Scale Communications","authors":"","doi":"10.1109/TMBMC.2026.3651917","DOIUrl":"https://doi.org/10.1109/TMBMC.2026.3651917","url":null,"abstract":"","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"11 4","pages":"1-16"},"PeriodicalIF":2.3,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=11339262","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145929418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Distance Underwater Target Search and Localization Using an AUV With Chemical Sensing 基于化学传感的水下航行器远距离水下目标搜索与定位
IF 2.3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-05 DOI: 10.1109/TMBMC.2025.3650122
Mingyue Cheng;Yingying Zhong;Runhua Chen;Zhangrui Ren;Menghan Zhao;Qiong Huang
With the increasing reliance on global air and sea transport, the need for effective underwater search mechanisms is becoming more pressing. However, complex marine environments presents substantial challenges for the recovery of crashed aircraft or sunken vessels. Existing underwater search methods rely heavily on acoustic communication, which is constrained in both range and energy. Although molecular communication offers considerable promise, there is a lack of search algorithms applicable to underwater scenarios. Therefore, we propose the hexagonal inverse gradient search (HIGS) algorithm for the search mission of lost objects underwater. HIGS employs the autonomous underwater vehicle (AUV) that navigates using molecular concentration gradients. To overcome the challenge of nearly zero-gradient regions, we develop a set of three-dimensional motion rules based on real-time chemical sensing, allowing AUVs to adjust their trajectories adaptively. Additionally, a zero-gradient escape strategy is incorporated to prevent the AUV from becoming trapped in local optima within complex underwater environments, thereby ensuring persistent and effective target search. Simulation results confirm the effectiveness of the proposed algorithm in underwater search missions.
随着对全球空中和海上运输的日益依赖,对有效的水下搜索机制的需求变得更加迫切。然而,复杂的海洋环境给失事飞机或沉船的回收带来了巨大的挑战。现有的水下搜索方法严重依赖于水声通信,这在范围和能量上都受到限制。尽管分子通信提供了相当大的前景,但缺乏适用于水下场景的搜索算法。因此,我们提出了六边形逆梯度搜索(HIGS)算法用于水下失物搜索任务。HIGS采用自主水下航行器(AUV),利用分子浓度梯度进行导航。为了克服接近零梯度区域的挑战,我们开发了一套基于实时化学传感的三维运动规则,允许auv自适应调整其轨迹。此外,采用零梯度逃生策略,防止AUV在复杂的水下环境中陷入局部最优状态,从而确保持久有效的目标搜索。仿真结果验证了该算法在水下搜索任务中的有效性。
{"title":"Long-Distance Underwater Target Search and Localization Using an AUV With Chemical Sensing","authors":"Mingyue Cheng;Yingying Zhong;Runhua Chen;Zhangrui Ren;Menghan Zhao;Qiong Huang","doi":"10.1109/TMBMC.2025.3650122","DOIUrl":"https://doi.org/10.1109/TMBMC.2025.3650122","url":null,"abstract":"With the increasing reliance on global air and sea transport, the need for effective underwater search mechanisms is becoming more pressing. However, complex marine environments presents substantial challenges for the recovery of crashed aircraft or sunken vessels. Existing underwater search methods rely heavily on acoustic communication, which is constrained in both range and energy. Although molecular communication offers considerable promise, there is a lack of search algorithms applicable to underwater scenarios. Therefore, we propose the hexagonal inverse gradient search (HIGS) algorithm for the search mission of lost objects underwater. HIGS employs the autonomous underwater vehicle (AUV) that navigates using molecular concentration gradients. To overcome the challenge of nearly zero-gradient regions, we develop a set of three-dimensional motion rules based on real-time chemical sensing, allowing AUVs to adjust their trajectories adaptively. Additionally, a zero-gradient escape strategy is incorporated to prevent the AUV from becoming trapped in local optima within complex underwater environments, thereby ensuring persistent and effective target search. Simulation results confirm the effectiveness of the proposed algorithm in underwater search missions.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"218-225"},"PeriodicalIF":2.3,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145929360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding Entanglement Through the Lens of Quantifiable Algebraic Structures: Application to Bird Navigation 通过可量化代数结构的镜头理解纠缠:在鸟类导航中的应用
IF 2.3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-01 DOI: 10.1109/TMBMC.2025.3650156
Sahil Imtiyaz;Serafim Rodrigues
We propose a unified mathematical meta-framework for long-distance navigation in birds, based on a bundle-theoretic representation of multisensory integration within evolving combinatorial structures. Various information streams—such as magnetic, celestial, olfactory, and landmark cues—are modeled as typed fibers over a time-varying simplicial base, which is reconstructed from behavioral trajectories and neural co-activity. In this framework, integration is framed as a global consistency problem: coherent system-level representations occur when there are globally compatible assignments across overlapping local contexts. This is equivalent to finding global sections of an evolving bundle. The tension between local and global perspectives is formalized in quantum theory through the concept of contextuality, which expresses the impossibility of a single, non-contextual global assignment that is consistent with all local marginals. In Bell-type scenarios, this aligns with operational non-locality and device-independent signatures of entanglement. We demonstrate that the same constraint semantics provide a precise mathematical connection between canonical contextuality models and biological cue integration, treating contextuality as a calculus for diagnosing and localizing incompatibilities in distributed representations. Our theory introduces two computable topological observables: critical simplices and interface loops. Critical simplices identify discrete remapping pivots where the structural scaffold must be reconfigured to restore consistency, while interface loops detect transient conflict cycles at the boundaries between different information streams. Together, these observables form a diagnostic “compass” that integrates cues onto a common scaffold, localizes incompatible overlaps, and predicts when spatial representations need to be remapped. We validate our framework using standard quantum contextuality scenarios, including Bell’s theorem and Klyachko–Can–Binicioǧlu–Shumovsky scenario (KCBS), successfully recovering established contextuality classifications through bundle obstructions and loop signatures. We then apply this framework to an anatomy-aware model of avian navigation, in which entanglement-capable cryptochrome/radical-pair dynamics serve as a microscopic source of non-classical correlations, without assuming that macroscopic entanglement occurs across neural circuits. In this model, microscopic non-classicality influences adaptive functions by leaving persistent, computable contextual footprints within the evolving biological scaffold, providing testable signatures at the level of remapping events and context-dependent cue integration.
基于进化组合结构中多感觉整合的束理论表示,我们提出了鸟类长距离导航的统一数学元框架。各种信息流——如磁、天体、嗅觉和地标线索——在一个时变的简单基础上被建模为类型纤维,该基础是由行为轨迹和神经协同活动重建的。在这个框架中,集成被定义为一个全局一致性问题:当在重叠的本地上下文中存在全局兼容的赋值时,就会出现一致的系统级表示。这相当于找到一个演化包的全局部分。局部和全局视角之间的张力在量子理论中通过情境性的概念形式化,它表达了与所有局部边缘一致的单一的、非情境的全局分配的不可能性。在bell类型的场景中,这与操作非局部性和设备无关的纠缠签名一致。我们证明了相同的约束语义在规范情境性模型和生物线索整合之间提供了精确的数学联系,将情境性视为诊断和定位分布式表示中的不兼容性的演算。我们的理论引入了两个可计算的拓扑观测:临界简单点和界面环。关键简单识别离散的重新映射枢纽,在那里结构支架必须重新配置以恢复一致性,而接口循环检测不同信息流之间边界的瞬态冲突循环。总之,这些观察结果形成了一个诊断“指南针”,将线索整合到一个共同的支架上,定位不相容的重叠部分,并预测何时需要重新映射空间表征。我们使用标准的量子上下文场景验证了我们的框架,包括贝尔定理和Klyachko-Can-Binicioǧlu-Shumovsky场景(KCBS),通过束阻塞和循环签名成功地恢复了已建立的上下文分类。然后,我们将该框架应用于鸟类导航的解剖学感知模型,其中具有纠缠能力的隐色素/自由基对动力学作为非经典相关性的微观来源,而不假设宏观纠缠发生在神经回路中。在这个模型中,微观的非经典性通过在进化的生物支架中留下持久的、可计算的上下文足迹来影响自适应功能,在重新映射事件和上下文相关线索整合的水平上提供可测试的特征。
{"title":"Understanding Entanglement Through the Lens of Quantifiable Algebraic Structures: Application to Bird Navigation","authors":"Sahil Imtiyaz;Serafim Rodrigues","doi":"10.1109/TMBMC.2025.3650156","DOIUrl":"https://doi.org/10.1109/TMBMC.2025.3650156","url":null,"abstract":"We propose a unified mathematical meta-framework for long-distance navigation in birds, based on a bundle-theoretic representation of multisensory integration within evolving combinatorial structures. Various information streams—such as magnetic, celestial, olfactory, and landmark cues—are modeled as typed fibers over a time-varying simplicial base, which is reconstructed from behavioral trajectories and neural co-activity. In this framework, integration is framed as a global consistency problem: coherent system-level representations occur when there are globally compatible assignments across overlapping local contexts. This is equivalent to finding global sections of an evolving bundle. The tension between local and global perspectives is formalized in quantum theory through the concept of contextuality, which expresses the impossibility of a single, non-contextual global assignment that is consistent with all local marginals. In Bell-type scenarios, this aligns with operational non-locality and device-independent signatures of entanglement. We demonstrate that the same constraint semantics provide a precise mathematical connection between canonical contextuality models and biological cue integration, treating contextuality as a calculus for diagnosing and localizing incompatibilities in distributed representations. Our theory introduces two computable topological observables: critical simplices and interface loops. Critical simplices identify discrete remapping pivots where the structural scaffold must be reconfigured to restore consistency, while interface loops detect transient conflict cycles at the boundaries between different information streams. Together, these observables form a diagnostic “compass” that integrates cues onto a common scaffold, localizes incompatible overlaps, and predicts when spatial representations need to be remapped. We validate our framework using standard quantum contextuality scenarios, including Bell’s theorem and Klyachko–Can–Binicioǧlu–Shumovsky scenario (KCBS), successfully recovering established contextuality classifications through bundle obstructions and loop signatures. We then apply this framework to an anatomy-aware model of avian navigation, in which entanglement-capable cryptochrome/radical-pair dynamics serve as a microscopic source of non-classical correlations, without assuming that macroscopic entanglement occurs across neural circuits. In this model, microscopic non-classicality influences adaptive functions by leaving persistent, computable contextual footprints within the evolving biological scaffold, providing testable signatures at the level of remapping events and context-dependent cue integration.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"279-297"},"PeriodicalIF":2.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146082133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Publication Information IEEE分子、生物和多尺度通信通讯学报
IF 2.3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-31 DOI: 10.1109/TMBMC.2025.3646292
{"title":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Publication Information","authors":"","doi":"10.1109/TMBMC.2025.3646292","DOIUrl":"https://doi.org/10.1109/TMBMC.2025.3646292","url":null,"abstract":"","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"i-i"},"PeriodicalIF":2.3,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=11320849","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145861226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HGNNMDA: Hybrid Graph Neural Networks for MiRNA-Disease Association Prediction HGNNMDA:用于mirna -疾病关联预测的混合图神经网络
IF 2.3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-24 DOI: 10.1109/TMBMC.2025.3648253
Nguyen-Phuc-Xuan Quynh;Hoai-Nhan Tran;Cheng Yan;Jianxin Wang
MicroRNAs are key biomarkers and therapeutic targets due to their role in regulating biological processes and disease progression. Traditional identification of miRNA-disease associations (MDAs) is costly and slow, motivating computational approaches. In this study, we propose HGNNMDA, a hybrid prediction model applying graph neural networks (GNNs) for predicting MDAs. The key novelty of HGNNMDA lies in its interactive dual-branch architecture, where each branch integrates both graph convolutional networks (GCNs) and graph attention networks (GATs) to extract robust features from diverse biological data sources. This design generates complementary feature representations by leveraging GCNs to capture structural associations through neighborhood aggregation, while employing GATs to prioritize the most relevant interactions via attention mechanisms, effectively overcoming limitations of single-architecture GNNs. The obtained feature vectors are then processed by XGBoosts to generate predictive scores, which are subsequently combined for final predictions. HGNNMDA outperforms seven recent methods in experimental validation on three datasets (HMDD v2.0, HMDD v3.2, and an independent dataset) and shows strong results in de novo validation and case studies. The source code in this work is available at https://github.com/npxquynhdhsp/HGNNMDA/.
由于其在调节生物过程和疾病进展中的作用,microrna是关键的生物标志物和治疗靶点。传统的mirna -疾病关联(mda)鉴定是昂贵和缓慢的,激励计算方法。在这项研究中,我们提出了HGNNMDA,这是一种应用图神经网络(gnn)预测mda的混合预测模型。HGNNMDA的关键新颖之处在于其交互式双分支架构,其中每个分支都集成了图卷积网络(GCNs)和图注意网络(GATs),以从不同的生物数据源中提取鲁棒特征。该设计通过利用GCNs通过邻域聚合捕获结构关联来生成互补特征表示,同时使用GATs通过注意机制优先考虑最相关的交互,有效克服了单一架构gnn的局限性。然后由xgboost处理获得的特征向量以生成预测分数,随后将其组合为最终预测。HGNNMDA在三个数据集(HMDD v2.0、HMDD v3.2和一个独立数据集)的实验验证中优于最近的7种方法,并在从头验证和案例研究中显示出强大的结果。本文的源代码可从https://github.com/npxquynhdhsp/HGNNMDA/获得。
{"title":"HGNNMDA: Hybrid Graph Neural Networks for MiRNA-Disease Association Prediction","authors":"Nguyen-Phuc-Xuan Quynh;Hoai-Nhan Tran;Cheng Yan;Jianxin Wang","doi":"10.1109/TMBMC.2025.3648253","DOIUrl":"https://doi.org/10.1109/TMBMC.2025.3648253","url":null,"abstract":"MicroRNAs are key biomarkers and therapeutic targets due to their role in regulating biological processes and disease progression. Traditional identification of miRNA-disease associations (MDAs) is costly and slow, motivating computational approaches. In this study, we propose HGNNMDA, a hybrid prediction model applying graph neural networks (GNNs) for predicting MDAs. The key novelty of HGNNMDA lies in its interactive dual-branch architecture, where each branch integrates both graph convolutional networks (GCNs) and graph attention networks (GATs) to extract robust features from diverse biological data sources. This design generates complementary feature representations by leveraging GCNs to capture structural associations through neighborhood aggregation, while employing GATs to prioritize the most relevant interactions via attention mechanisms, effectively overcoming limitations of single-architecture GNNs. The obtained feature vectors are then processed by XGBoosts to generate predictive scores, which are subsequently combined for final predictions. HGNNMDA outperforms seven recent methods in experimental validation on three datasets (HMDD v2.0, HMDD v3.2, and an independent dataset) and shows strong results in de novo validation and case studies. The source code in this work is available at <uri>https://github.com/npxquynhdhsp/HGNNMDA/</uri>.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"136-145"},"PeriodicalIF":2.3,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145929548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secure Event-Triggered Molecular Communication—Information Theoretic Perspective and Optimal Performance 安全事件触发分子通信——信息论视角与最优性能
IF 2.3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-22 DOI: 10.1109/TMBMC.2025.3647208
Wafa Labidi;Vida Gholamian;Yaning Zhao;Christian Deppe;Holger Boche
Molecular Communication (MC) is an emerging field of research focused on understanding how cells in the human body communicate and exploring potential medical applications. In theoretical analysis, the goal is to investigate cellular communication mechanisms and develop nanomachine-assisted therapies to combat diseases. Since cells transmit information by releasing molecules at varying intensities, this process is commonly modeled using Poisson channels. In our study, we consider a discrete-time Poisson channel (DTPC). MC is often event-driven, making traditional Shannon communication an unsuitable performance metric. Instead, we adopt the identification framework introduced by Ahlswede and Dueck. In this approach, the receiver is only concerned with detecting whether a specific message of interest has been transmitted. Unlike Shannon transmission codes, the size of identification (ID) codes for a discrete memoryless channel (DMC) increases doubly exponentially with blocklength when using randomized encoding. This remarkable property makes the ID paradigm significantly more efficient than classical Shannon transmission in terms of energy consumption and hardware requirements. Another critical aspect of MC, influenced by the concept of the Internet of Bio-NanoThings, is security. In-body communication must be protected against potential eavesdroppers. To address this, we first analyze the DTPC for randomized identification (RI) and then extend our study to secure randomized identification (SRI). We derive capacity formulas for both RI and SRI, providing a comprehensive understanding of their performance and security implications.
分子通信(Molecular Communication, MC)是一门新兴的研究领域,主要研究人体细胞如何进行通信并探索潜在的医学应用。在理论分析方面,目标是研究细胞通信机制并开发纳米机器辅助疗法来对抗疾病。由于细胞通过释放不同强度的分子来传递信息,这个过程通常用泊松通道来模拟。在我们的研究中,我们考虑一个离散时间泊松信道(DTPC)。MC通常是事件驱动的,这使得传统的Shannon通信成为不合适的性能度量。相反,我们采用了Ahlswede和Dueck引入的识别框架。在这种方法中,接收方只关心检测感兴趣的特定消息是否已发送。与香农传输码不同,使用随机编码时,离散无内存信道(DMC)的标识码(ID)的大小随块长度呈指数倍增长。这一显著特性使得ID范式在能耗和硬件要求方面明显比经典香农传输更高效。受生物纳米物联网概念影响,MC的另一个关键方面是安全性。身体内的通信必须受到保护,以防潜在的窃听者。为了解决这个问题,我们首先分析了随机识别(RI)的DTPC,然后扩展我们的研究以确保随机识别(SRI)。我们推导了RI和SRI的容量公式,提供了对它们的性能和安全含义的全面理解。
{"title":"Secure Event-Triggered Molecular Communication—Information Theoretic Perspective and Optimal Performance","authors":"Wafa Labidi;Vida Gholamian;Yaning Zhao;Christian Deppe;Holger Boche","doi":"10.1109/TMBMC.2025.3647208","DOIUrl":"https://doi.org/10.1109/TMBMC.2025.3647208","url":null,"abstract":"Molecular Communication (MC) is an emerging field of research focused on understanding how cells in the human body communicate and exploring potential medical applications. In theoretical analysis, the goal is to investigate cellular communication mechanisms and develop nanomachine-assisted therapies to combat diseases. Since cells transmit information by releasing molecules at varying intensities, this process is commonly modeled using Poisson channels. In our study, we consider a discrete-time Poisson channel (DTPC). MC is often event-driven, making traditional Shannon communication an unsuitable performance metric. Instead, we adopt the identification framework introduced by Ahlswede and Dueck. In this approach, the receiver is only concerned with detecting whether a specific message of interest has been transmitted. Unlike Shannon transmission codes, the size of identification (ID) codes for a discrete memoryless channel (DMC) increases doubly exponentially with blocklength when using randomized encoding. This remarkable property makes the ID paradigm significantly more efficient than classical Shannon transmission in terms of energy consumption and hardware requirements. Another critical aspect of MC, influenced by the concept of the Internet of Bio-NanoThings, is security. In-body communication must be protected against potential eavesdroppers. To address this, we first analyze the DTPC for randomized identification (RI) and then extend our study to secure randomized identification (SRI). We derive capacity formulas for both RI and SRI, providing a comprehensive understanding of their performance and security implications.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"265-278"},"PeriodicalIF":2.3,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145982187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Communication in Bounded Spherical Region With Anomalous Diffusion Phenomenon 具有异常扩散现象的有界球形区域中的分子通信
IF 2.3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-17 DOI: 10.1109/TMBMC.2025.3645247
T. Sai Krishna Charitha;Lokendra Chouhan;Abhishek K. Gupta;Rik Dey;Eswar Kadali;Sairam Mente;Rituraj;Prabhat K. Sharma
In this work, we develop the channel model of a molecular communication (MC) system with molecules propagating via anomalous diffusion in a confined environment, in particular, inside a spherical region. The MC system consists of an absorbing receiver located at the center of the region and a point transmitter, whereas the outer boundary is fully reflecting. We first obtain the concentration profile of molecules inside the region at a given time. Further, we derive the hitting rate and hitting probability to characterize the channel.
在这项工作中,我们开发了分子通信(MC)系统的通道模型,其中分子在受限环境中通过异常扩散传播,特别是在球形区域内。MC系统由位于区域中心的吸收接收器和点发射机组成,而外部边界是全反射的。我们首先得到给定时间区域内分子的浓度分布。进一步,我们导出了命中率和命中概率来表征信道。
{"title":"Molecular Communication in Bounded Spherical Region With Anomalous Diffusion Phenomenon","authors":"T. Sai Krishna Charitha;Lokendra Chouhan;Abhishek K. Gupta;Rik Dey;Eswar Kadali;Sairam Mente;Rituraj;Prabhat K. Sharma","doi":"10.1109/TMBMC.2025.3645247","DOIUrl":"https://doi.org/10.1109/TMBMC.2025.3645247","url":null,"abstract":"In this work, we develop the channel model of a molecular communication (MC) system with molecules propagating via anomalous diffusion in a confined environment, in particular, inside a spherical region. The MC system consists of an absorbing receiver located at the center of the region and a point transmitter, whereas the outer boundary is fully reflecting. We first obtain the concentration profile of molecules inside the region at a given time. Further, we derive the hitting rate and hitting probability to characterize the channel.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"105-110"},"PeriodicalIF":2.3,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145886657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guest Editorial Introduction to the Special Feature on the 9th Workshop on Molecular Communications 第九届分子通讯研讨会专题导论
IF 2.3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-17 DOI: 10.1109/TMBMC.2025.3637924
Jens Kirchner;Bhuvana Krishnaswamy;Lin Lin;Laura Galluccio;Nunzio Tuccitto
{"title":"Guest Editorial Introduction to the Special Feature on the 9th Workshop on Molecular Communications","authors":"Jens Kirchner;Bhuvana Krishnaswamy;Lin Lin;Laura Galluccio;Nunzio Tuccitto","doi":"10.1109/TMBMC.2025.3637924","DOIUrl":"https://doi.org/10.1109/TMBMC.2025.3637924","url":null,"abstract":"","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"11 4","pages":"482-485"},"PeriodicalIF":2.3,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=11301984","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145778251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Publication Information IEEE分子、生物和多尺度通信通讯学报
IF 2.3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-16 DOI: 10.1109/TMBMC.2025.3637917
{"title":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Publication Information","authors":"","doi":"10.1109/TMBMC.2025.3637917","DOIUrl":"https://doi.org/10.1109/TMBMC.2025.3637917","url":null,"abstract":"","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"11 4","pages":"C2-C2"},"PeriodicalIF":2.3,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=11302010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145760888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1