The economic value of reducing mortality due to noncommunicable diseases and injuries

IF 58.7 1区 医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Nature Medicine Pub Date : 2024-09-27 DOI:10.1038/s41591-024-03248-4
Stéphane Verguet, Sarah Bolongaita, Angela Y. Chang, Diego S. Cardoso, Gretchen A. Stevens
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Abstract

With population aging, national health systems face difficult trade-offs in allocating resources. The World Bank launched the Healthy Longevity Initiative to generate evidence for investing in policies that can improve healthy longevity and human capital. As part of this initiative, we quantified the economic value of reducing avoidable mortality from major noncommunicable diseases and injuries. We estimated avoidable mortality—the difference between lowest-achieved mortality frontiers and projected mortality trajectories—for each cause of death, for 2000, 2019 and 2050, and for geographic regions, with high-income countries, India and China considered separately; we applied economic values to these estimates. The economic value of reducing cardiovascular disease avoidable mortality would be large for both sexes in all regions, reaching 2–8% of annual income in 2019. For cancers, it would be 5–6% of annual income in high-income countries and China, and for injuries, it would be around 5% in sub-Saharan Africa and Latin America and the Caribbean. Despite the large uncertainty surrounding our estimates, we offer economic values for reducing avoidable mortality by cause and metrics comparable to annual incomes, which enable multisectoral priority setting and are relevant for high-level policy discussions around budget and resource allocations. This study reports substantial economic value in annual income if mortality due to cardiovascular diseases, cancers and injuries is reduced.

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降低非传染性疾病和伤害死亡率的经济价值
随着人口老龄化的加剧,国家卫生系统在分配资源时面临着艰难的权衡。世界银行发起了 "健康长寿倡议"(Healthy Longevity Initiative),旨在为改善健康长寿和人力资本的政策投资提供证据。作为该倡议的一部分,我们量化了降低主要非传染性疾病和伤害导致的可避免死亡率的经济价值。我们估算了 2000 年、2019 年和 2050 年每种死因的可避免死亡率--最低死亡率前沿与预测死亡率轨迹之间的差值,并对高收入国家、印度和中国等地理区域进行了单独考虑;我们对这些估算值应用了经济价值。在所有地区,降低心血管疾病可避免死亡率的经济价值对男女两性来说都很大,2019 年将达到年收入的 2-8% 。就癌症而言,在高收入国家和中国,经济价值将达到年收入的 5-6%;就伤害而言,在撒哈拉以南非洲以及拉丁美洲和加勒比海地区,经济价值将达到 5%左右。尽管我们的估算存在很大的不确定性,但我们提供了按病因和与年收入相当的度量来降低可避免死亡率的经济价值,这有助于确定多部门的优先事项,并与围绕预算和资源分配的高层政策讨论相关。
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来源期刊
Nature Medicine
Nature Medicine 医学-生化与分子生物学
CiteScore
100.90
自引率
0.70%
发文量
525
审稿时长
1 months
期刊介绍: Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors. Nature Medicine consider all types of clinical research, including: -Case-reports and small case series -Clinical trials, whether phase 1, 2, 3 or 4 -Observational studies -Meta-analyses -Biomarker studies -Public and global health studies Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.
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