Microbial extracellular polymeric substances in the environment, technology and medicine

IF 69.2 1区生物学 Q1 MICROBIOLOGY Nature Reviews Microbiology Pub Date : 2024-09-27 DOI:10.1038/s41579-024-01098-y

Hans-Curt Flemming, Eric D. van Hullebusch, Brenda J. Little, Thomas R. Neu, Per H. Nielsen, Thomas Seviour, Paul Stoodley, Jost Wingender, Stefan Wuertz

{"title":"Microbial extracellular polymeric substances in the environment, technology and medicine","authors":"Hans-Curt Flemming, Eric D. van Hullebusch, Brenda J. Little, Thomas R. Neu, Per H. Nielsen, Thomas Seviour, Paul Stoodley, Jost Wingender, Stefan Wuertz","doi":"10.1038/s41579-024-01098-y","DOIUrl":null,"url":null,"abstract":"<p>Microbial biofilms exhibit a self-produced matrix of extracellular polymeric substances (EPS), including polysaccharides, proteins, extracellular DNA and lipids. EPS promote interactions of the biofilm with other cells and sorption of organics, metals and chemical pollutants, and they facilitate cell adhesion at interfaces and ensure matrix cohesion. EPS have roles in various natural environments, such as soils, sediments and marine habitats. In addition, EPS are relevant in technical environments, such as wastewater and drinking water treatment facilities, and water distribution systems, and they contribute to biofouling and microbially influenced corrosion. In medicine, EPS protect pathogens within the biofilm against the host immune system and antimicrobials, and emerging evidence suggests that EPS can represent potential virulence factors. By contrast, EPS yield a wide range of valuable products that include their role in self-repairing concrete. In this Review, we aim to explore EPS as a functional unit of biofilms in the environment, in technology and in medicine.</p>","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":null,"pages":null},"PeriodicalIF":69.2000,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Microbiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1038/s41579-024-01098-y","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MICROBIOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Microbial biofilms exhibit a self-produced matrix of extracellular polymeric substances (EPS), including polysaccharides, proteins, extracellular DNA and lipids. EPS promote interactions of the biofilm with other cells and sorption of organics, metals and chemical pollutants, and they facilitate cell adhesion at interfaces and ensure matrix cohesion. EPS have roles in various natural environments, such as soils, sediments and marine habitats. In addition, EPS are relevant in technical environments, such as wastewater and drinking water treatment facilities, and water distribution systems, and they contribute to biofouling and microbially influenced corrosion. In medicine, EPS protect pathogens within the biofilm against the host immune system and antimicrobials, and emerging evidence suggests that EPS can represent potential virulence factors. By contrast, EPS yield a wide range of valuable products that include their role in self-repairing concrete. In this Review, we aim to explore EPS as a functional unit of biofilms in the environment, in technology and in medicine.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

环境、技术和医学中的微生物胞外聚合物物质

微生物生物膜显示出一种由细胞外高分子物质（EPS）组成的自产基质，包括多糖、蛋白质、细胞外 DNA 和脂质。EPS 可促进生物膜与其他细胞的相互作用以及对有机物、金属和化学污染物的吸附，还能促进细胞在界面上的粘附并确保基质的内聚力。EPS 在土壤、沉积物和海洋栖息地等各种自然环境中发挥作用。此外，EPS 还与技术环境有关，如废水和饮用水处理设施以及输水系统，它们会造成生物污垢和受微生物影响的腐蚀。在医学上，EPS 保护生物膜内的病原体免受宿主免疫系统和抗菌剂的侵害，新的证据表明，EPS 可能是潜在的致病因子。相比之下，EPS 可产生多种有价值的产品，包括在混凝土自我修复中的作用。在本综述中，我们将探讨 EPS 在环境、技术和医学中作为生物膜功能单元的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Nature Reviews Microbiology 生物-微生物学

CiteScore

74.00

自引率

0.50%

发文量

149

审稿时长

6-12 weeks

期刊介绍： At Nature Reviews Microbiology, our goal is to become the leading source of reviews and commentaries for the scientific community we cater to. We are dedicated to publishing articles that are not only authoritative but also easily accessible, supplementing them with clear and concise figures, tables, and other visual aids. Our objective is to offer an unparalleled service to authors, referees, and readers, and we continuously strive to maximize the usefulness and impact of each article we publish. With a focus on Reviews, Perspectives, and Comments spanning the entire field of microbiology, our wide scope ensures that the work we feature reaches the widest possible audience.

期刊最新文献

Microbial extracellular polymeric substances in the environment, technology and medicine The rising mpox crisis ISME19 Publisher Correction: Microorganisms, climate change, and the Sustainable Development Goals: progress and challenges. Publisher Correction: Unveiling plasmid diversity in nature.