Victor Shen BS , Reed Andrews MD , Odion Binitie MD , Brian T. Palumbo MD
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引用次数: 0
Abstract
Adverse local tissue reaction (ALTR) from the release of chromium and cobalt ions in metal-on-metal total hip arthroplasty (MoM THA) is a well-reported complication, but there is little evidence suggesting that this inflammatory reaction causes malignancy. We present a 69-year-old female with MoM THA who developed synovial sarcoma (SS). She underwent mass resection and revision THA. Postoperative pathologic analysis revealed the unanticipated diagnosis of SS. She subsequently underwent chemotherapy, sarcoma resection, and endoprosthetic reconstruction. We hypothesize that the SS developed from an ALTR in the setting of failed MoM THA. Given the paucity of data on possible malignant transformation of an ALTR to SS, we advise surgeons to consider potential malignancies when diagnosing ALTR in the setting of failed MoM THA bearings.
期刊介绍：
Arthroplasty Today is a companion journal to the Journal of Arthroplasty. The journal Arthroplasty Today brings together the clinical and scientific foundations for joint replacement of the hip and knee in an open-access, online format. Arthroplasty Today solicits manuscripts of the highest quality from all areas of scientific endeavor that relate to joint replacement or the treatment of its complications, including those dealing with patient outcomes, economic and policy issues, prosthetic design, biomechanics, biomaterials, and biologic response to arthroplasty. The journal focuses on case reports. It is the purpose of Arthroplasty Today to present material to practicing orthopaedic surgeons that will keep them abreast of developments in the field, prove useful in the care of patients, and aid in understanding the scientific foundation of this subspecialty area of joint replacement. The international members of the Editorial Board provide a worldwide perspective for the journal''s area of interest. Their participation ensures that each issue of Arthroplasty Today provides the reader with timely, peer-reviewed articles of the highest quality.
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