Enhanced biosensing with rhombic ring resonator in 2D photonic crystals for proteinuria detection

IF 3.1 3区物理与天体物理 Q2 Engineering Optik Pub Date : 2024-09-20 DOI:10.1016/j.ijleo.2024.172041

Yashaswini P R , Venkateswara Rao Kolli , Geetha L , Gautam Narayan Nirala , Srikanth P. C

{"title":"Enhanced biosensing with rhombic ring resonator in 2D photonic crystals for proteinuria detection","authors":"Yashaswini P R , Venkateswara Rao Kolli , Geetha L , Gautam Narayan Nirala , Srikanth P. C","doi":"10.1016/j.ijleo.2024.172041","DOIUrl":null,"url":null,"abstract":"<div><div>A two-dimensional (2D) photonic crystal (PC) based biosensor was developed and studied to detect albumin and urea levels in patients with proteinuria. Rhombic ring resonator structures are built with the help of FDTD (Finite Difference Time Domain). After the fields are computed using the 2D-FDTD approach, the normalized transmission spectra are produced by applying the Fast Fourier Transform (FFT) to them. The full width at half maximum (FWHM), Quality factor (Q-factor), Sensitivity, Figure of Merit (FOM), and Limit of Detection (LOD) are 15,466.5, 110 nm/RIU, 0.12 nm, 1100 <em>RIU</em><sup><em>−</em>1</sup> and 54<em>.</em>34<em>X</em>10<sup><em>−</em>6</sup> RIU respectively, when the resonant wavelength is 1546 nm. The novelty of this the project lies in combining 2D photonic crystal, innovative rhombic ring resonator design and high-performance parameters. The achieved values are notably high, which is a novel achievement in the field of biosensing. The project aims to contribute to the field of biosensors and provide a potential tool for healthcare professionals to monitor diabetes, proteinuria, kidney function and overall health.</div></div>","PeriodicalId":19513,"journal":{"name":"Optik","volume":"316 ","pages":"Article 172041"},"PeriodicalIF":3.1000,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Optik","FirstCategoryId":"101","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0030402624004406","RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Engineering","Score":null,"Total":0}

引用次数: 0

Abstract

A two-dimensional (2D) photonic crystal (PC) based biosensor was developed and studied to detect albumin and urea levels in patients with proteinuria. Rhombic ring resonator structures are built with the help of FDTD (Finite Difference Time Domain). After the fields are computed using the 2D-FDTD approach, the normalized transmission spectra are produced by applying the Fast Fourier Transform (FFT) to them. The full width at half maximum (FWHM), Quality factor (Q-factor), Sensitivity, Figure of Merit (FOM), and Limit of Detection (LOD) are 15,466.5, 110 nm/RIU, 0.12 nm, 1100 RIU⁻¹ and 54.34X10⁻⁶ RIU respectively, when the resonant wavelength is 1546 nm. The novelty of this the project lies in combining 2D photonic crystal, innovative rhombic ring resonator design and high-performance parameters. The achieved values are notably high, which is a novel achievement in the field of biosensing. The project aims to contribute to the field of biosensors and provide a potential tool for healthcare professionals to monitor diabetes, proteinuria, kidney function and overall health.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

利用二维光子晶体中的菱形环谐振器增强生物传感，用于蛋白尿检测

开发并研究了一种基于二维（2D）光子晶体（PC）的生物传感器，用于检测蛋白尿患者体内的白蛋白和尿素水平。在 FDTD（有限差分时域）的帮助下，建立了菱形环谐振器结构。在使用二维-有限差分时域方法计算场之后，通过快速傅立叶变换（FFT）生成归一化透射光谱。当谐振波长为 1546 nm 时，半最大全宽 (FWHM)、品质因数 (Q-factor)、灵敏度、优越性图 (FOM) 和检测限 (LOD) 分别为 15466.5、110 nm/RIU、0.12 nm、1100 RIU-1 和 54.34X10-6 RIU。该项目的新颖之处在于将二维光子晶体、创新的菱形环谐振器设计和高性能参数相结合。所达到的数值非常高，是生物传感领域的一项新成就。该项目旨在为生物传感器领域做出贡献，并为医护人员监测糖尿病、蛋白尿、肾功能和整体健康提供一种潜在的工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Optik 物理-光学

CiteScore

6.90

自引率

12.90%

发文量

1471

审稿时长

46 days

期刊介绍： Optik publishes articles on all subjects related to light and electron optics and offers a survey on the state of research and technical development within the following fields: Optics: -Optics design, geometrical and beam optics, wave optics- Optical and micro-optical components, diffractive optics, devices and systems- Photoelectric and optoelectronic devices- Optical properties of materials, nonlinear optics, wave propagation and transmission in homogeneous and inhomogeneous materials- Information optics, image formation and processing, holographic techniques, microscopes and spectrometer techniques, and image analysis- Optical testing and measuring techniques- Optical communication and computing- Physiological optics- As well as other related topics.