{"title":"Stochastic network to model the global spreading of respiratory diseases: From SARS-CoV-2 to pathogen X pandemic","authors":"Leonardo López , Xavier Rodó","doi":"10.1016/j.ecoinf.2024.102827","DOIUrl":null,"url":null,"abstract":"<div><div>The recent COVID-19 pandemic has underscored the vulnerability of global health systems. Emerging in November 2019 in Hubei, China, COVID-19 has had far-reaching consequences, affecting every corner of the globe. The impact has been particularly severe, causing widespread collapse of public health systems and contraction of the world economy. The imposition of stringent sanitary restrictions by the majority of countries, in response to SARS-CoV-2, disrupted various economic sectors on a massive scale. The existing gap between developed and underdeveloped countries further complicates the global scenario, raising uncertainties. This concern is amplified when considering the potential threat of other infectious diseases with dynamics akin to SARS-CoV-2, such as a new recombining H5N1 flu strain. Such a strain, if easily transmissible among humans, could lead to another pandemic. In this study, we introduce a stochastic network model designed to assess control strategies on a global scale. This model enables us to project how new variants, evading immunity, might respond to either a coordinated global response from governments or a complete lack of coordination. Our connectivity model between countries is based on a network of contacts derived from actual commercial air connectivity data. The disease dynamics within each country are simulated using a population-based approach with differential equations. The epidemiological model is fine-tuned using real SARS-CoV-2 data reported by various countries from 2019 to 2023.</div></div>","PeriodicalId":51024,"journal":{"name":"Ecological Informatics","volume":"83 ","pages":"Article 102827"},"PeriodicalIF":5.8000,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ecological Informatics","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1574954124003698","RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The recent COVID-19 pandemic has underscored the vulnerability of global health systems. Emerging in November 2019 in Hubei, China, COVID-19 has had far-reaching consequences, affecting every corner of the globe. The impact has been particularly severe, causing widespread collapse of public health systems and contraction of the world economy. The imposition of stringent sanitary restrictions by the majority of countries, in response to SARS-CoV-2, disrupted various economic sectors on a massive scale. The existing gap between developed and underdeveloped countries further complicates the global scenario, raising uncertainties. This concern is amplified when considering the potential threat of other infectious diseases with dynamics akin to SARS-CoV-2, such as a new recombining H5N1 flu strain. Such a strain, if easily transmissible among humans, could lead to another pandemic. In this study, we introduce a stochastic network model designed to assess control strategies on a global scale. This model enables us to project how new variants, evading immunity, might respond to either a coordinated global response from governments or a complete lack of coordination. Our connectivity model between countries is based on a network of contacts derived from actual commercial air connectivity data. The disease dynamics within each country are simulated using a population-based approach with differential equations. The epidemiological model is fine-tuned using real SARS-CoV-2 data reported by various countries from 2019 to 2023.
期刊介绍:
The journal Ecological Informatics is devoted to the publication of high quality, peer-reviewed articles on all aspects of computational ecology, data science and biogeography. The scope of the journal takes into account the data-intensive nature of ecology, the growing capacity of information technology to access, harness and leverage complex data as well as the critical need for informing sustainable management in view of global environmental and climate change.
The nature of the journal is interdisciplinary at the crossover between ecology and informatics. It focuses on novel concepts and techniques for image- and genome-based monitoring and interpretation, sensor- and multimedia-based data acquisition, internet-based data archiving and sharing, data assimilation, modelling and prediction of ecological data.