RNAs kiss and translate in germ granules

IF 17.3 1区生物学 Q1 CELL BIOLOGY Nature Cell Biology Pub Date : 2024-10-01 DOI:10.1038/s41556-024-01502-y

Ameya P. Jalihal, Zachary M. Geisterfer, Amy S. Gladfelter

引用次数: 0

Abstract

The assembly of germ granules remains unknown, but recent attention to the role of RNA structure in membrane-less organelle assembly is changing our understanding of RNAs in the cell. Two studies now show how RNA–RNA interactions drive germ granule assembly and how germ granules spatially regulate embryonic mRNA translation.

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RNA 在胚芽颗粒中接吻和翻译

胚芽颗粒的组装仍然未知，但最近对 RNA 结构在无膜细胞器组装中作用的关注正在改变我们对细胞中 RNA 的认识。现在有两项研究显示了 RNA-RNA 相互作用是如何驱动胚芽颗粒组装的，以及胚芽颗粒是如何在空间上调控胚胎 mRNA 翻译的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Cell Biology 生物-细胞生物学

CiteScore

28.40

自引率

0.90%

发文量

219

审稿时长

3 months

期刊介绍： Nature Cell Biology, a prestigious journal, upholds a commitment to publishing papers of the highest quality across all areas of cell biology, with a particular focus on elucidating mechanisms underlying fundamental cell biological processes. The journal's broad scope encompasses various areas of interest, including but not limited to: -Autophagy -Cancer biology -Cell adhesion and migration -Cell cycle and growth -Cell death -Chromatin and epigenetics -Cytoskeletal dynamics -Developmental biology -DNA replication and repair -Mechanisms of human disease -Mechanobiology -Membrane traffic and dynamics -Metabolism -Nuclear organization and dynamics -Organelle biology -Proteolysis and quality control -RNA biology -Signal transduction -Stem cell biology

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