An improved algorithm for salient object detection of microscope based on U2-Net.

IF 2.6 4区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Medical & Biological Engineering & Computing Pub Date : 2025-02-01 Epub Date: 2024-09-26 DOI:10.1007/s11517-024-03205-w
Yunchai Li, Run Fang, Nangang Zhang, Chengsheng Liao, Xiaochang Chen, Xiaoyu Wang, Yunfei Luo, Leheng Li, Min Mao, Yunlong Zhang
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Abstract

With the rapid advancement of modern medical technology, microscopy imaging systems have become one of the key technologies in medical image analysis. However, manual use of microscopes presents issues such as operator dependency, inefficiency, and time consumption. To enhance the efficiency and accuracy of medical image capture and reduce the burden of subsequent quantitative analysis, this paper proposes an improved microscope salient object detection algorithm based on U2-Net, incorporating deep learning technology. The improved algorithm first enhances the network's key information extraction capability by incorporating the Convolutional Block Attention Module (CBAM) into U2-Net. It then optimizes network complexity by constructing a Simple Pyramid Pooling Module (SPPM) and uses Ghost convolution to achieve model lightweighting. Additionally, data augmentation is applied to the slides to improve the algorithm's robustness and generalization. The experimental results show that the size of the improved algorithm model is 72.5 MB, which represents a 56.85% reduction compared to the original U2-Net model size of 168.0 MB. Additionally, the model's prediction accuracy has increased from 92.24 to 97.13%, providing an efficient means for subsequent image processing and analysis tasks in microscopy imaging systems.

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基于 U2-Net 的显微镜突出物检测改进算法。
随着现代医学技术的飞速发展,显微成像系统已成为医学图像分析的关键技术之一。然而,人工使用显微镜存在操作依赖性强、效率低、耗时长等问题。为了提高医学图像采集的效率和准确性,减轻后续定量分析的负担,本文结合深度学习技术,提出了一种基于 U2-Net 的改进型显微镜突出物检测算法。改进算法首先通过在 U2-Net 中加入卷积块注意力模块(CBAM)来增强网络的关键信息提取能力。然后,它通过构建简单金字塔池化模块(SPPM)来优化网络复杂性,并使用幽灵卷积来实现模型轻量化。此外,还对幻灯片进行了数据增强,以提高算法的鲁棒性和泛化能力。实验结果表明,改进算法模型的大小为 72.5 MB,与原始 U2-Net 模型的 168.0 MB 相比,减少了 56.85%。此外,该模型的预测准确率从 92.24% 提高到 97.13%,为显微成像系统的后续图像处理和分析任务提供了有效手段。
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来源期刊
Medical & Biological Engineering & Computing
Medical & Biological Engineering & Computing 医学-工程:生物医学
CiteScore
6.00
自引率
3.10%
发文量
249
审稿时长
3.5 months
期刊介绍: Founded in 1963, Medical & Biological Engineering & Computing (MBEC) continues to serve the biomedical engineering community, covering the entire spectrum of biomedical and clinical engineering. The journal presents exciting and vital experimental and theoretical developments in biomedical science and technology, and reports on advances in computer-based methodologies in these multidisciplinary subjects. The journal also incorporates new and evolving technologies including cellular engineering and molecular imaging. MBEC publishes original research articles as well as reviews and technical notes. Its Rapid Communications category focuses on material of immediate value to the readership, while the Controversies section provides a forum to exchange views on selected issues, stimulating a vigorous and informed debate in this exciting and high profile field. MBEC is an official journal of the International Federation of Medical and Biological Engineering (IFMBE).
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