Peripheral nerve microanatomy: new insights into possible mechanisms for block success.

IF 5.1 2区 医学 Q1 ANESTHESIOLOGY Regional Anesthesia and Pain Medicine Pub Date : 2024-09-26 DOI:10.1136/rapm-2024-105721
Graeme A McLeod, Amy Sadler, Andre Boezaart, Xavier Sala-Blanch, Miguel Angel Reina
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Abstract

Postmortem histology and in vivo, animal-based ultra-high-definition microultrasound demonstrate a complex array of non-communicating adipose tissue compartments enclosed by fascia. Classic nerve block mechanisms and histology do not consider this tissue. Injected local anesthetic agents can occupy any of these adipose compartments, which may explain the significant differences in outcomes such as success rates, onset time, block density, duration of nerve block, and secondary continuous block failure. Furthermore, these adipose tissue compartments may influence injection pressures, making conclusions about needle tip location unreliable. This educational review will explain the neural anatomy associated with these fatty compartments in detail and suggest how they may affect block outcomes.

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周围神经显微解剖学:对阻滞成功可能机制的新认识。
死后组织学和活体动物超高清微超声显示,筋膜包裹着一系列复杂的非交流脂肪组织区。传统的神经阻滞机制和组织学都没有考虑到这种组织。注射的局麻药可以占据这些脂肪组织区块中的任何一个,这可能是成功率、起始时间、阻滞密度、神经阻滞持续时间和继发性持续阻滞失败等结果存在显著差异的原因。此外,这些脂肪组织区可能会影响注射压力,从而使针尖位置的结论不可靠。本教育综述将详细解释与这些脂肪区相关的神经解剖学,并提出它们可能如何影响阻滞效果。
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来源期刊
CiteScore
8.50
自引率
11.80%
发文量
175
审稿时长
6-12 weeks
期刊介绍: Regional Anesthesia & Pain Medicine, the official publication of the American Society of Regional Anesthesia and Pain Medicine (ASRA), is a monthly journal that publishes peer-reviewed scientific and clinical studies to advance the understanding and clinical application of regional techniques for surgical anesthesia and postoperative analgesia. Coverage includes intraoperative regional techniques, perioperative pain, chronic pain, obstetric anesthesia, pediatric anesthesia, outcome studies, and complications. Published for over thirty years, this respected journal also serves as the official publication of the European Society of Regional Anaesthesia and Pain Therapy (ESRA), the Asian and Oceanic Society of Regional Anesthesia (AOSRA), the Latin American Society of Regional Anesthesia (LASRA), the African Society for Regional Anesthesia (AFSRA), and the Academy of Regional Anaesthesia of India (AORA).
期刊最新文献
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