Determining the N-Glycan and Collagen/Extracellular Matrix Protein Compositions in a Novel Outcome Cohort of Prostate Cancer Tissue Microarrays Using MALDI-MSI.
Jordan P Hartig, Kaitlyn Bejar, Lyndsay E A Young, Grace Grimsley, Jennifer R Bethard, Dean A Troyer, Javier Hernandez, Jennifer D Wu, Joseph E Ippolito, Lauren E Ball, Jonathan A L Gelfond, Teresa L Johnson-Pais, Anand S Mehta, Robin J Leach, Peggi M Angel, Richard R Drake
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Abstract
Significance: Using matrix-assisted laser desorption/ionization mass spectrometry imaging techniques on a unique cohort of prostate cancer tissues, we highlighted several molecular characteristics of matrix that have potential to act as early predictors of prostate cancer metastasis.
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