Blood Plasma Film Multifractal Scanning in COVID-19 Consequences Diagnostics.

Journal of biophotonics Pub Date : 2024-11-01 Epub Date: 2024-09-26 DOI:10.1002/jbio.202400356
Alexander Ushenko, Natalia Pavlyukovich, Oksana Khukhlina, Olexander Pavlyukovich, Iryna Soltys, Alexander Dubolazov, Yurii Ushenko, Ivan Gordey, Jun Zheng, Zhebo Chen, Lin Bin
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Abstract

A 3D phase scanning method was applied to study blood plasma facies, generating layered polarization maps of the object field. The most sensitive parameters to changes in birefringence distribution were identified. Multifractal analysis using wavelet transforms and fractal dimension spectra provided specific insights into the scale self-similarity of the polarization maps. The multifractal spectra of ellipticity distributions were algorithmically derived, revealing that the third- and fourth-order statistical moments were most sensitive to changes in the supramolecular networks of the facies. These findings were successfully applied to differentiate post-COVID-19 effects with high accuracy.

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COVID-19 后果诊断中的血浆膜多分形扫描。
应用三维相位扫描方法研究血浆面,生成对象场的分层偏振图。确定了对双折射分布变化最敏感的参数。利用小波变换和分形维度光谱进行的多分形分析为了解偏振图的尺度自相似性提供了具体线索。通过算法得出了椭圆度分布的多分形光谱,发现三阶和四阶统计矩对面层超分子网络的变化最为敏感。这些发现被成功地应用于高精度区分后 COVID-19 效应。
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