Initiating an Insulin Safety Campaign to reduce the incidence of glycemic harm events for hospitalized adults 65 and older.

Michelle Cohen, Kristen de Grandpre, William M Herlihy, Lise Cooper
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Abstract

Background: During calendar years 2021 through 2023, our health system admitted 200,837 persons 18 years and older with diabetes, of which 61% (n = 123,393) were 65 years and older with orders for insulin administration. The incidence of diabetes among hospitalized persons 65 and older continues to increase in the United States, with 24 million adults 65 and older with diabetes reported in 2020. Insulin, a high-risk medication, has the potential for adverse drug events, which can cause significant harm to patients, potentially resulting in death. With the 2023 initiation of voluntary electronic clinical quality measures reporting for severe glycemic harm events from the Centers for Medicare Services, the study team saw an opportunity to evaluate and standardize insulin-related practices across the system.

Methods: We implemented an Insulin Safety Campaign (ISC), to review, evaluate, and standardize insulin-related processes across our health system. The primary goal was to reduce severe glycemic harm events system-wide. Insulin-related practices were reviewed for best practice alignment and standardized. Outcomes were measured according to the Centers for Medicare and Medicaid Services' electronic clinical quality measures reporting guidelines.

Results: Comparing pre-and post-implementation results, all five medical centers achieved statistically significant reductions in sever hyper- and hypoglycemic harm events.

Conclusions: Through a collaborative effort, we were able to identify, address, and reduce insulin-related process variabilities through standardization, reducing the percentage of severe glycemic harm events and improving blood glucose management in our hospitalized persons 65 and older.

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启动胰岛素安全运动,降低 65 岁及以上住院成年人的血糖伤害事件发生率。
背景:在 2021 年至 2023 年期间,我们的医疗系统将收治 200,837 名 18 岁及以上的糖尿病患者,其中 61%(n=123,393)为 65 岁及以上的糖尿病患者,并下达了胰岛素用药医嘱。在美国,65 岁及以上住院患者的糖尿病发病率持续上升,据报告,2020 年将有 2400 万 65 岁及以上的成年人患有糖尿病。胰岛素是一种高风险药物,有可能发生药物不良事件,对患者造成重大伤害,甚至可能导致死亡。随着 2023 年美国联邦医疗保险服务中心开始对严重血糖危害事件进行自愿性电子临床质量测量报告,研究小组看到了在整个系统内评估和规范胰岛素相关实践的机会:我们开展了胰岛素安全运动(ISC),对整个医疗系统中与胰岛素相关的流程进行审查、评估和标准化。主要目标是在全系统范围内减少严重的血糖伤害事件。我们对胰岛素相关实践进行了审查,以确保最佳实践的一致性和标准化。结果根据医疗保险和医疗补助服务中心的电子临床质量测量报告指南进行测量:结果:对比实施前后的结果,所有五家医疗中心的严重高血糖和低血糖危害事件都有了统计学意义上的显著减少:通过共同努力,我们能够通过标准化来识别、解决并减少与胰岛素相关的流程差异,从而降低严重血糖伤害事件的发生率,并改善 65 岁及以上住院患者的血糖管理。
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