Characterization of Lemongrass Extract (Cymbopagon citratus) Nanoemulsion and Its Application as an Antibiofilm Agent in Acrylic Resin.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-07-01 Epub Date: 2024-07-31 DOI:10.4103/jpbs.jpbs_418_24
Vinna K Sugiaman, Rosalina I Saputri, Silvia Naliani, Jane A V Wibisono, Jeffrey, Wayan L Demolsky, Wahyu Widowati, Agung Novianto
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Abstract

Background: An antimicrobial agent is needed for denture cleaning, such as lemongrass (LG), which has a bioactive antimicrobial component.

Methods: This research analyzed LG extract nanoparticles with a particle size analyzer, ZPA, and biofilm formation inhibition on resin acrylic surfaces.

Results: We found that there is high stability in nanoparticle size, while other concentrations, including chlorhexidine as a positive control, did not show any statistical differences.

Conclusion: Lemongrass oil nanoemulsion has proved to be an antibiofilm and effective as a denture cleaning agent because of its ability to inhibit Streptococcus mutans and Candida albicans growth.

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柠檬草提取物(Cymbopagon citratus)纳米乳液的特性及其作为丙烯酸树脂抗生物膜剂的应用。
背景:义齿清洁需要一种抗菌剂,如柠檬草(LG):义齿清洁需要一种抗菌剂,如柠檬草(LG),它具有生物活性抗菌成分:本研究使用粒度分析仪、ZPA 分析了柠檬草提取物纳米颗粒对树脂丙烯酸表面生物膜形成的抑制作用:结果:我们发现纳米粒子的粒径具有很高的稳定性,而其他浓度(包括作为阳性对照的洗必泰)则没有显示出任何统计学差异:结论:柠檬草油纳米乳液具有抑制变异链球菌和白色念珠菌生长的能力,因此被证明是一种抗生物膜和有效的义齿清洁剂。
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