Comparative Evaluation of Feracrylum and Chlorhexidine in Nonsurgical Periodontal Therapy in Chronic Periodontitis: A Clinicomicrobiological Study.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-07-01 Epub Date: 2024-07-31 DOI:10.4103/jpbs.jpbs_387_24
Karthika Janardhan, Hiral Parikh
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Abstract

Background: One common inflammatory illness that affects periodontal tissues is chronic periodontitis. By lowering inflammation and getting rid of periodontal bacteria, nonsurgical periodontal management is essential for treating chronic periodontitis. The objective of this study was to evaluate the effectiveness of chlorhexidine and feracrylum in nonsurgical periodontal management for persistent periodontitis.

Techniques: As part of their periodontal therapy, 50 patients with a diagnosis of chronic periodontitis were randomized into two groups: first got chlorhexidine, while other Feracrylum received feracrylum. Microbiological analysis and clinical parameters were measured at baseline and 3 months later.

Results: Clinical metrics showed a considerable improvement in both groups. Comparing feracrylum to chlorhexidine, the former showed stronger antibacterial action against periodontal infections.

Conclusion: For nonsurgical periodontal management of chronic periodontitis, feracrylum shows similar effectiveness to chlorhexidine. Furthermore, feracrylum has better antibacterial activity against pathogens of the periodontal tissues, indicating that it might be used as a substitute antimicrobial agent in periodontal management.

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慢性牙周炎非手术牙周治疗中 Feracrylum 和洗必泰的比较评估:临床微生物学研究
背景:影响牙周组织的一种常见炎症性疾病是慢性牙周炎。通过降低炎症和清除牙周细菌,非手术牙周治疗对治疗慢性牙周炎至关重要。本研究的目的是评估洗必泰和亚 feracrylum 在治疗顽固性牙周炎的非手术牙周治疗中的有效性:作为牙周治疗的一部分,50 名确诊为慢性牙周炎的患者被随机分为两组:一组使用洗必泰,另一组使用阿魏酸。分别在基线和 3 个月后对微生物分析和临床指标进行测量:结果:两组的临床指标均有显著改善。结果:临床指标显示,两组患者的病情均有显著改善,阿魏酸钙与洗必泰相比,前者对牙周感染的抗菌作用更强:结论:对于慢性牙周炎的非手术牙周治疗,阿魏酸胶与洗必泰的疗效相似。此外,阿魏酰对牙周组织的病原体具有更好的抗菌活性,这表明阿魏酰可作为牙周治疗中的替代抗菌剂。
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