Evaluating the Efficacy of Platelet-Rich Plasma (PRP) in Accelerating Healing and Reducing Complications in Oral Surgery.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-07-01 Epub Date: 2024-04-24 DOI:10.4103/jpbs.jpbs_84_24
Liza Mohanty, Abhishek Harish, Sachin B Mangalekar, Ankur Jethlia, Honey Lunkad, Jessica Y Jeevitha, Ramanpal S Makkad
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Abstract

Background: The process of curing and regaining the integrity of damaged tissues is known as healing. An autologous concentration of platelets embedded in plasma is known as platelet-rich plasma (PRP).

Aim: This study was conducted to evaluate the role of PRP in the fast healing of wounds and complications in oral surgical procedures.

Materials and methods: A total of 60 patients who underwent different oral surgical procedures were included in this study. PRP was placed in the surgical area after surgical procedures and recalled at the 2nd, 4th, and 6th month postoperatively. There was the assessment of soft tissue healing by measuring the probing depth in teeth adjacent to the surgical area and hard tissue healing in the form of alveolar bone density and alveolar bone height. The assessment of postoperative complications was also conducted.

Results: The decrease in the probing depth at different follow-ups was greater in PRP patients showing better and fast soft tissue healing. The increase in alveolar height and alveolar bone density at different follow-ups was greater in the PRP group showing better and fast hard tissue healing. The frequency of complications, such as trismus and pain, was lesser in patients with PRP.

Conclusion: The wound healing was at increased rate with reduced complications on using PRP in oral surgical procedures.

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评估富血小板血浆 (PRP) 在加速口腔手术愈合和减少并发症方面的功效。
背景:治愈和恢复受损组织完整性的过程被称为愈合。目的:本研究旨在评估 PRP 在口腔外科手术伤口快速愈合和并发症方面的作用:本研究共纳入了 60 名接受过不同口腔外科手术的患者。在手术后将 PRP 置入手术区域,并在术后第 2、4 和 6 个月进行复查。通过测量手术区邻近牙齿的探诊深度评估软组织愈合情况,并通过牙槽骨密度和牙槽骨高度评估硬组织愈合情况。此外,还对术后并发症进行了评估:结果:在不同的随访中,PRP 患者探诊深度的下降幅度更大,表明软组织愈合更好、更快。在不同的随访中,PRP 组牙槽骨高度和牙槽骨密度的增加幅度更大,表明硬组织愈合更好更快。使用 PRP 的患者出现三叉症和疼痛等并发症的频率较低:结论:在口腔外科手术中使用 PRP,伤口愈合率提高,并发症减少。
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