Outcomes of a policy to prioritize populations with expected healthcare barriers for subsidized preexposure prophylaxis care in Amsterdam, the Netherlands.

IF 3.4 2区 医学 Q3 IMMUNOLOGY AIDS Pub Date : 2025-01-01 Epub Date: 2024-09-27 DOI:10.1097/QAD.0000000000004027
Eline Wijstma, Vita W Jongen, Anders Boyd, Henry J C de Vries, Maarten F Schim van der Loeff, Maria Prins, Elske Hoornenborg
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Abstract

Objective: The Dutch HIV preexposure prophylaxis (PrEP) pilot provided subsidized PrEP care to maximum 2900 individuals at a time in Amsterdam. Populations with expected barriers to accessing PrEP elsewhere were prioritized for program inclusion. We evaluated their prior sexual health service engagement and PrEP need.

Design: Cross-sectional analysis using enrolment data.

Methods: We included individuals ever enrolled in the PrEP program at the Center for Sexual Health (CSH) Amsterdam between 2019 and 2023. We calculated the proportion belonging to higher-priority groups (i.e., <25 years old, transgender, sex worker, uninsured or migrant). We defined classes of sexual health service engagement in the 12 months preceding enrolment using latent class analysis (LCA). We compared engagement classes, sexual behavior and positivity of HIV and sexually transmitted infections (STI) between higher- and lower-priority groups.

Results: 2004/4075 (49%) individuals enrolled belonged to higher-priority groups. LCA showed three classes of prior engagement: "newly engaged" (14%, n  = 551) were new to the CSH-Amsterdam; "PrEP initiators" (40%, n  = 1642) previously visited the CSH-Amsterdam but had not used PrEP; "PrEP experienced" individuals (46%, n  = 1882) previously accessed PrEP. Higher-priority groups were more often "newly engaged" or "PrEP-initiators" than "PrEP-experienced". Higher-priority groups less often had condomless anal sex with casual partners or chemsex in the prior 6 months. Positivity of bacterial STI was similar between higher-priority ( n  = 300/2004, 15.0%) and lower-priority ( n  = 315/2071, 15.2%) groups. 13/14 HIV diagnoses at enrolment were in higher-priority groups.

Conclusion: Higher-priority populations had less often previously used sexual health services and accounted for most new HIV diagnoses at enrolment. Engaging these populations in sexual healthcare, including PrEP, should be stressed.

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荷兰阿姆斯特丹一项政策的成果:一项横断面研究,该政策优先考虑有预期医疗障碍的人群,为其提供 PrEP 护理补贴。
目标:荷兰艾滋病暴露前预防(PrEP)试点项目在阿姆斯特丹为最多 2,900 人提供有补贴的 PrEP 治疗。预计在其他地方获得 PrEP 存在障碍的人群被优先纳入该计划。我们评估了他们之前的性健康服务参与情况和 PrEP 需求:设计:利用注册数据进行横断面分析:我们纳入了 2019-2023 年间曾在阿姆斯特丹性健康中心(CSH)注册 PrEP 项目的个人。结果:2,004/4,075(49%)名注册者属于高优先群体。LCA 显示了三个先前参与类别:"新加入者"(14%,n = 551)是第一次来阿姆斯特丹 CSH;"PrEP 发起者"(40%,n = 1642)以前来过阿姆斯特丹 CSH,但没有使用过 PrEP;"PrEP 体验者"(46%,n = 1882)以前使用过 PrEP。与 "有 PrEP 经验者 "相比,优先级较高的群体更多是 "新参与 "或 "PrEP 启动者"。优先级较高的群体在过去六个月中与临时性伴侣发生无安全套肛交或同性性行为的情况较少。细菌性 STI 阳性率在优先级较高组(n = 300/2,004,15.0%)和优先级较低组(n = 315/2,071,15.2%)之间相似。13/14的艾滋病病毒感染者在入学时被诊断为艾滋病病毒感染者:结论:较高优先级人群以前较少使用性健康服务,在注册时新诊断出的 HIV 感染者中占大多数。应强调让这些人群参与性保健,包括 PrEP。
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来源期刊
AIDS
AIDS 医学-病毒学
CiteScore
5.90
自引率
5.30%
发文量
478
审稿时长
3 months
期刊介绍: ​​​​​​​​​​​​​​​​​Publishing the very latest ground breaking research on HIV and AIDS. Read by all the top clinicians and researchers, AIDS has the highest impact of all AIDS-related journals. With 18 issues per year, AIDS guarantees the authoritative presentation of significant advances. The Editors, themselves noted international experts who know the demands of your work, are committed to making AIDS the most distinguished and innovative journal in the field. Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.
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