Unveiling the Hidden Dangers: Massive Allergic Dermatitis After Hyaluronic Acid Injection.

IF 1.9 4区 医学 Q3 DERMATOLOGY Clinical, Cosmetic and Investigational Dermatology Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI:10.2147/CCID.S477847
Fengfeng Guo, Yuxi Xia, Qingqian Wei, Jun Zhuang, Jinge Li, Jintian Hu
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Abstract

The increasing use of hyaluronic acid (HA) implants has made adverse effects more apparent. Here, we present a rare case of massive allergic dermatitis due to HA injections. We performed dermoscopy and color ultrasound, which clarified that this was an allergic dermatitis caused by fillers, and analyzed the possible causes of the allergy. Common treatments were compared, and the advantages of 5-FU-based treatment regimens and their associated mechanisms were noted. A low dose of 5-fluorouracil and triamcinolone acetonide was administered to the patient's entire face and neck, and significant efficacy was achieved. We aimed to gather evidence on extensive dermatitis caused by HA injection, provide new perspectives and solutions for subsequent HA injections, and promote further research on the potential mechanisms of extensive skin inflammation and allergies caused by local HA injections.

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揭开隐藏的危险:注射透明质酸后的大规模过敏性皮炎。
随着透明质酸(HA)植入物的使用越来越多,其不良反应也越来越明显。在此,我们介绍一例罕见的因注射透明质酸(HA)引起的大面积过敏性皮炎病例。我们进行了皮肤镜检查和彩色超声波检查,明确了这是由填充物引起的过敏性皮炎,并分析了过敏的可能原因。我们对常见的治疗方法进行了比较,并指出了以 5-FU 为基础的治疗方案的优势及其相关机制。对患者的整个面部和颈部使用小剂量的 5-氟尿嘧啶和曲安奈德,取得了显著疗效。我们的目的是收集HA注射引起广泛皮炎的证据,为后续HA注射提供新的视角和解决方案,并促进对局部HA注射引起广泛皮肤炎症和过敏的潜在机制的进一步研究。
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来源期刊
CiteScore
2.80
自引率
4.30%
发文量
353
审稿时长
16 weeks
期刊介绍: Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.
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