Gender differences between smoking and the risk of hip fracture.

IF 2.4 3区医学 Q3 ENDOCRINOLOGY & METABOLISM Journal of Bone and Mineral Metabolism Pub Date : 2024-09-26 DOI:10.1007/s00774-024-01546-y

Yilun Tang, Yan Xu, Jinhui Song, Chen Zhang, Run Tian, Kunzheng Wang, Pei Yang

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Abstract

Objective: This study aimed to estimate the relation between cigarette smoking and hip fracture in men compared with women using a meta-analytic approach.

Methods: On March 1, 2024, prospective cohort studies were searched from PubMed, Embase and Cochrane library systems. The gender difference in the relationship between smoking and hip fracture risk was evaluated by random effect model.

Results: Eleven prospective cohort studies involving data from 2,689,620 individuals were selected for meta-analysis. The ratio of relative risk (RRR) of hip fractures in current smokers was significantly higher in men than in women (RRR: 1.10; 95%CI: 1.00 - 1.20; P = 0.047), while no evidence of sex differences in former smoking and hip fracture risk (RRR: 0.98; 95%CI: 0.88 - 1.10; P = 0.759).

Conclusions: The male-to-female RRR of hip fractures increased in current smokers, whereas no sex difference was found in the relationship between former smoking and the risk of hip fractures.

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吸烟与髋部骨折风险之间的性别差异。

研究目的本研究旨在采用荟萃分析法估算男性吸烟与女性髋部骨折之间的关系：2024年3月1日，在PubMed、Embase和Cochrane图书馆系统中检索了前瞻性队列研究。通过随机效应模型评估了吸烟与髋部骨折风险之间的性别差异：荟萃分析选取了 11 项前瞻性队列研究，涉及 2,689,620 人的数据。当前吸烟者发生髋部骨折的相对风险比（RRR）男性明显高于女性（RRR：1.10；95%CI：1.00 - 1.20；P = 0.047），而以往吸烟与髋部骨折风险之间无性别差异（RRR：0.98；95%CI：0.88 - 1.10；P = 0.759）：结论：目前吸烟者髋部骨折的男女比例比增加，而曾经吸烟与髋部骨折风险之间的关系未发现性别差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Bone and Mineral Metabolism 医学-内分泌学与代谢

CiteScore

6.30

自引率

3.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal of Bone and Mineral Metabolism (JBMM) provides an international forum for researchers and clinicians to present and discuss topics relevant to bone, teeth, and mineral metabolism, as well as joint and musculoskeletal disorders. The journal welcomes the submission of manuscripts from any country. Membership in the society is not a prerequisite for submission. Acceptance is based on the originality, significance, and validity of the material presented. The journal is aimed at researchers and clinicians dedicated to improvements in research, development, and patient-care in the fields of bone and mineral metabolism.