EXPRESSION OF CONCERN: Ap1 Mediates uPA/uPAR Induced FUT4 Expression and Trophoblast Invasion

IF 3 3区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of cellular biochemistry Pub Date : 2024-09-30 DOI:10.1002/jcb.30657

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引用次数: 0

Abstract

EXPRESSION OF CONCERN: Q. Zheng, Y. Yang, X. Cui, D. Zhang, S. Liu, and Q. Yan, “AP1 Mediates uPA/uPAR Induced FUT4 Expression and Trophoblast Invasion,” Journal of Cellular Biochemistry 119, no. 8 (2018): 6442-6451, https://doi.org/10.1002/jcb.26648.

This Expression of Concern is for the above article, published online on 26 December 2017 in Wiley Online Library (wileyonlinelibrary.com), has been issued by agreement between the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals, LLC.

The Expression of Concern has been agreed due to concerns raised by third parties regarding the data presented in the article. Specifically, overlaps have been detected in the invasion assay images between the “uPAR+c-Fos siRNA” and “uPAR+TIIA” groups in Figure 5C. Further investigation by the publisher revealed additional overlaps in the migration assay images between the “uPAR+SP600125” and “uPAR+TIIA” groups in the same figure. The authors explained that these overlaps occurred due to errors during the figure assembly and provided revised images to correct the mistakes. However, the replacement images provided by the authors failed to reproduce the results of the originally published images. Consequently, the journal has decided to issue this Expression of Concern to inform and alert readers.

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表达关切：Ap1 介导 uPA/uPAR 诱导的 FUT4 表达和滋养层母细胞侵袭。

表达关注：Q. Zheng, Y. Yang, X. Cui, D. Zhang, S. Liu, and Q. Yan, "AP1 Mediates uPA/uPAR Induced FUT4 Expression and Trophoblast Invasion," Journal of Cellular Biochemistry 119, no：6442-6451, https://doi.org/10.1002/jcb.26648.This Expression of Concern 是针对 2017 年 12 月 26 日在线发表在 Wiley Online Library（wileyonlinelibrary.com）上的上述文章，已由期刊主编 Christian Behl 和 Wiley Periodicals, LLC 协议发布。之所以同意发布 Expression of Concern，是因为第三方对文章中提供的数据提出了担忧。具体而言，图 5C 中 "uPAR+c-Fos siRNA "组和 "uPAR+TIIA "组的侵袭试验图像中发现了重叠。出版商进一步调查后发现，图 5C 中 "uPAR+SP600125 "组和 "uPAR+TIA "组之间的迁移实验图像也有重叠。作者解释说，这些重叠是由于拼图过程中的错误造成的，并提供了修改后的图片以纠正错误。然而，作者提供的替换图片未能再现最初发表的图片的结果。因此，本刊决定发布本关注函，以告知和提醒读者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of cellular biochemistry 生物-生化与分子生物学

CiteScore

9.90

自引率

0.00%

发文量

164

审稿时长

1 months

期刊介绍： The Journal of Cellular Biochemistry publishes descriptions of original research in which complex cellular, pathogenic, clinical, or animal model systems are studied by biochemical, molecular, genetic, epigenetic or quantitative ultrastructural approaches. Submission of papers reporting genomic, proteomic, bioinformatics and systems biology approaches to identify and characterize parameters of biological control in a cellular context are encouraged. The areas covered include, but are not restricted to, conditions, agents, regulatory networks, or differentiation states that influence structure, cell cycle & growth control, structure-function relationships.