Advances in Zinc-Containing Bioactive Glasses: A Comprehensive Review.

IF 5 3区医学 Q1 ENGINEERING, BIOMEDICAL Journal of Functional Biomaterials Pub Date : 2024-09-08 DOI:10.3390/jfb15090258

Fariborz Sharifianjazi, Mohammadjavad Sharifianjazi, Maryam Irandoost, Ketevan Tavamaishvili, Mehdi Mohabatkhah, Maziar Montazerian

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Abstract

Bioactive glasses (BGs) have attracted significant attention in the biomaterials field due to their ability to promote soft and hard tissue regeneration and their potential for various clinical applications. BGs offer enriched features through the integration of different therapeutic inorganic ions within their composition. These ions can trigger specific responses in the body conducive to a battery of applications. For example, zinc, a vital trace element, plays a role in numerous physiological processes within the human body. By incorporating zinc, BGs can inhibit bacterial growth, exert anti-inflammatory effects, and modify bioactivity, promoting better integration with surrounding tissues when used in scaffolds for tissue regeneration. This article reviews recent developments in zinc-containing BGs (ZBGs), focusing on their synthesis, physicochemical, and biological properties. ZBGs represent a significant advancement in applications extending beyond bone regeneration. Overall, their biological roles hold promise for various applications, such as bone tissue engineering, wound healing, and biomedical coatings. Ongoing research continues to explore the potential benefits of ZBGs and to optimize their properties for diverse clinical applications.

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含锌生物活性玻璃的研究进展：全面回顾。

生物活性玻璃（BGs）因其促进软硬组织再生的能力及其在各种临床应用中的潜力而在生物材料领域备受关注。生物活性玻璃通过在其成分中整合不同的治疗性无机离子，提供了丰富的功能。这些离子可在体内引发特定的反应，有利于各种应用。例如，锌是一种重要的微量元素，在人体内的许多生理过程中发挥作用。通过加入锌，BGs 可以抑制细菌生长，发挥消炎作用，并改变生物活性，在用于组织再生支架时促进与周围组织更好地融合。本文回顾了含锌 BGs（ZBGs）的最新发展，重点介绍了它们的合成、物理化学和生物学特性。ZBGs 在骨再生以外的应用领域取得了重大进展。总体而言，它们的生物作用为骨组织工程、伤口愈合和生物医学涂层等各种应用带来了希望。目前的研究仍在继续，以探索 ZBGs 的潜在益处，并优化其特性，使其适用于各种临床应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Functional Biomaterials Engineering-Biomedical Engineering

CiteScore

4.60

自引率

4.20%

发文量

226

审稿时长

11 weeks

期刊介绍： Journal of Functional Biomaterials (JFB, ISSN 2079-4983) is an international and interdisciplinary scientific journal that publishes regular research papers (articles), reviews and short communications about applications of materials for biomedical use. JFB covers subjects from chemistry, pharmacy, biology, physics over to engineering. The journal focuses on the preparation, performance and use of functional biomaterials in biomedical devices and their behaviour in physiological environments. Our aim is to encourage scientists to publish their results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Several topical special issues will be published. Scope: adhesion, adsorption, biocompatibility, biohybrid materials, bio-inert materials, biomaterials, biomedical devices, biomimetic materials, bone repair, cardiovascular devices, ceramics, composite materials, dental implants, dental materials, drug delivery systems, functional biopolymers, glasses, hyper branched polymers, molecularly imprinted polymers (MIPs), nanomedicine, nanoparticles, nanotechnology, natural materials, self-assembly smart materials, stimuli responsive materials, surface modification, tissue devices, tissue engineering, tissue-derived materials, urological devices.