Advances in the Clinical Study of Nuclear Overhauser Enhancement

IF 3.5 2区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Magnetic Resonance Imaging Pub Date : 2024-09-28 DOI:10.1002/jmri.29623

Nannan Zhao MS, Yuanyu Shen MD, Dafa Shi MD, Yumeng Mao MS, Guangsong Wang MD, Gang Xiao PhD, Dongyuan Xu MD, Gen Yan MD

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Abstract

Nuclear overhauser enhancement is a confounding factor arising from the in vivo application of a chemical exchange saturation transfer technique in which two nuclei in close proximity undergo dipole cross-relaxation. Several studies have shown applicability and efficacy of nuclear overhauser enhancement in observing tumors and other lesions in vivo. Thus, this effect could become an emerging molecular imaging research tool for many diseases. Moreover, nuclear overhauser enhancement has the advantages of simplicity, noninvasiveness, and high resolution and has become a major focus of current research. In this review, we summarize the principles and applications of nuclear overhauser enhancement.

Level of Evidence

Technical Efficacy

Stage 1

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核超声增强临床研究进展》。

核过豪森增强是在体内应用化学交换饱和转移技术时产生的一种干扰因素，在这种技术中，两个相邻的原子核会发生偶极交叉松弛。多项研究表明，核过倍增效应在观察体内肿瘤和其他病变方面具有适用性和有效性。因此，这种效应可能成为许多疾病的新兴分子成像研究工具。此外，核超焦增强具有简单、无创和高分辨率等优点，已成为当前研究的重点。在这篇综述中，我们将总结核超微增强的原理和应用。证据等级：2 技术效率：第 1 阶段。

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来源期刊

Journal of Magnetic Resonance Imaging 医学-核医学

CiteScore

9.70

自引率

6.80%

发文量

494

审稿时长

2 months

期刊介绍： The Journal of Magnetic Resonance Imaging (JMRI) is an international journal devoted to the timely publication of basic and clinical research, educational and review articles, and other information related to the diagnostic applications of magnetic resonance.