Impact of continuous glucose monitoring on emergency department visits and all-cause hospitalization rates among Medicaid beneficiaries with type 2 diabetes treated with multiple daily insulin or basal insulin therapy.

IF 2.3 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Journal of managed care & specialty pharmacy Pub Date : 2024-10-01 DOI:10.18553/jmcp.2024.30.10-b.s21
Irl B Hirsch, Bhavya Sree Burugapalli, Laura Brandner, Yeesha Poon, Marie Frazzitta, Lakshmi Godavarthi, Naunihal Virdi
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Abstract

Background: The increasing prevalence of diabetes in the United States continues to drive a steady rise in health care resource utilization, especially emergency department visits and all-cause hospitalizations, and the associated costs.

Objective: To investigate the impact of continuous glucose monitoring (CGM) on emergency department visits and all-cause hospitalizations among Medicaid beneficiaries with type 2 diabetes (T2D) treated with multiple daily insulin injections (MDIs) or basal insulin therapy (BIT) in a real-world setting.

Methods: In this retrospective, 12-month analysis, we used the Inovalon Insights claims dataset to evaluate the effects of CGM acquisition on emergency department visits and all-cause hospitalizations in the Managed Medicaid population. The analysis included 44,941 beneficiaries with T2D who were treated with MDIs (n = 35,367) or BIT (n = 9,574). Primary outcomes were changes in the number of emergency department visits and all-cause hospitalizations following 6 months after acquisition of CGM (post-index period) compared with 6 month prior to CGM acquisition (pre-index period). The first claim for CGM was the index date. Inclusion criteria were as follows: aged younger than 65 years, diagnosis of T2D, claims for short- or rapid-acting insulin (MDI group) or basal insulin (not rapid-acting) (BIT group), acquisition of a CGM device between January 1, 2017, and September 30, 2022, and continuous enrollment in their health plan throughout the pre-index and post-index periods.

Results: In the MDI group, all-cause inpatient hospitalization rates decreased from 3.25 to 2.29 events/patient-year (hazard ratio = 0.12; 95% CI = 0.11-0.13; P < 0.001) and emergency department visit rates decreased from 2.15 to 1.86 events/patient-year (hazard ratio = 0.52; 95% CI = 0.50-0.53; P < 0.001). In the BIT group, all-cause inpatient hospitalization rates decreased from 1.63 to 1.39 events/patient-year (hazard ratio = 0.11; 95% CI = 0.09-0.12; P < 0.001) and emergency department visit rates decreased from 1.60 to 1.43 events/patient-year (hazard ratio = 0.47; 95% CI = 0.44-0.50; P < 0.001).

Conclusions: Acquisition of CGM is associated with significant reductions in emergency department visits and all-cause hospitalizations among people with T2D treated with MDIs or BIT.

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背景:美国糖尿病发病率不断上升,导致医疗资源利用率持续上升,尤其是急诊就诊率和全因住院率以及相关费用:美国糖尿病患病率不断上升,导致医疗资源利用率(尤其是急诊就诊率和全因住院率)和相关费用持续上升:调查在真实世界环境中,连续血糖监测(CGM)对每日多次胰岛素注射(MDI)或基础胰岛素治疗(BIT)的 2 型糖尿病(T2D)医疗补助受益人的急诊就诊率和全因住院率的影响:在这项为期 12 个月的回顾性分析中,我们使用 Inovalon Insights 索偿数据集来评估 CGM 的购置对管理式医疗补助人群急诊就诊和全因住院的影响。分析对象包括 44,941 名接受 MDIs(n = 35,367 人)或 BIT(n = 9,574 人)治疗的 T2D 患者。主要结果是 CGM 使用 6 个月后(指数后阶段)与 CGM 使用前 6 个月(指数前阶段)相比,急诊就诊次数和全因住院次数的变化。首次申请 CGM 的日期为指标日期。纳入标准如下:年龄小于65岁,诊断为T2D,申请短效或速效胰岛素(MDI组)或基础胰岛素(非速效)(BIT组),在2017年1月1日至2022年9月30日期间购买CGM设备,并在指数前和指数后期间持续加入其医疗保险:在MDI组,全因住院率从3.25例/患者-年降至2.29例/患者-年(危险比=0.12;95% CI=0.11-0.13;P<0.001),急诊就诊率从2.15例/患者-年降至1.86例/患者-年(危险比=0.52;95% CI=0.50-0.53;P<0.001)。在BIT组,全因住院率从1.63例/患者-年降至1.39例/患者-年(危险比=0.11;95% CI=0.09-0.12;P<0.001),急诊就诊率从1.60例/患者-年降至1.43例/患者-年(危险比=0.47;95% CI=0.44-0.50;P<0.001):结论:在使用 MDIs 或 BIT 治疗的 T2D 患者中,使用 CGM 可显著减少急诊就诊率和全因住院率。
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来源期刊
Journal of managed care & specialty pharmacy
Journal of managed care & specialty pharmacy Health Professions-Pharmacy
CiteScore
3.50
自引率
4.80%
发文量
131
期刊介绍: JMCP welcomes research studies conducted outside of the United States that are relevant to our readership. Our audience is primarily concerned with designing policies of formulary coverage, health benefit design, and pharmaceutical programs that are based on evidence from large populations of people. Studies of pharmacist interventions conducted outside the United States that have already been extensively studied within the United States and studies of small sample sizes in non-managed care environments outside of the United States (e.g., hospitals or community pharmacies) are generally of low interest to our readership. However, studies of health outcomes and costs assessed in large populations that provide evidence for formulary coverage, health benefit design, and pharmaceutical programs are of high interest to JMCP’s readership.
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