Clinical Characteristics of Children with Acute Post-Streptococcal Glomerulonephritis and Re-Evaluation of Patients with Artificial Intelligence.

IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Medeniyet medical journal Pub Date : 2024-09-30 DOI:10.4274/MMJ.galenos.2024.09382
Emre Leventoglu, Mustafa Soran
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Abstract

Objective: Acute post-streptococcal glomerulonephritis (APSGN) is a common cause of acute glomerulonephritis in children. The condition may present as acute nephritic and/or nephrotic syndrome and rarely as rapidly progressive glomerulonephritis. ChatGPT (OpenAI, San Francisco, California, United States of America) has been developed as a chat robot supported by artificial intelligence (AI). In this study, we evaluated whether AI can be used in the follow-up of patients with APSGN.

Methods: The clinical characteristics of patients with APSGN were noted from patient records. Twelve questions about APSGN were directed to ChatGPT 3.5. The accuracy of the answers was evaluated by the researchers. Then, the clinical features of the patients were transferred to ChatGPT 3.5 and the follow-up management of the patients was examined.

Results: The study included 11 patients with an average age of 9.08±3.96 years. Eight (72.7%) patients had elevated creatinine and 10 (90.9%) had hematuria and/or proteinuria. Anti-streptolysin O was high in all patients (955±353 IU/mL) and C3 was low in 9 (81.8%) patients (0.56±0.34 g/L). Hypertensive encephalopathy, nephrotic syndrome, and rapidly progressive glomerulonephritis were observed in three patients. Normal creatinine levels were achieved in all patients. Questions assessing the definition, epidemiologic characteristics, pathophysiologic mechanisms, diagnosis, and treatment of APSGN were answered correctly by ChatGPT 3.5. All patients were diagnosed with APSGN, and the treatment steps applied by clinicians were similarly recommended by ChatGPT 3.5.

Conclusions: The insights and recommendations offered by ChatGPT for patients with APSGN can be an asset in the care and management of patients. With AI applications, clinicians can review treatment decisions and create more effective treatment plans.

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链球菌感染后急性肾小球肾炎患儿的临床特征及人工智能对患者的再评估
目的:链球菌感染后急性肾小球肾炎(APSGN)是儿童急性肾小球肾炎的常见病因。该病可表现为急性肾炎和/或肾病综合征,很少表现为快速进展性肾小球肾炎。ChatGPT(OpenAI,美国加利福尼亚州旧金山)是一款由人工智能(AI)支持的聊天机器人。在这项研究中,我们评估了人工智能是否可用于 APSGN 患者的随访:方法:我们从患者病历中记录了 APSGN 患者的临床特征。在 ChatGPT 3.5 中提出了 12 个有关 APSGN 的问题。研究人员对答案的准确性进行了评估。然后,将患者的临床特征转入 ChatGPT 3.5,并对患者的随访管理进行检查:研究共纳入 11 名患者,平均年龄为(9.08±3.96)岁。8例(72.7%)患者血肌酐升高,10例(90.9%)患者出现血尿和/或蛋白尿。所有患者的抗链球菌溶解素 O 均较高(955±353 IU/mL),9 名(81.8%)患者的 C3 较低(0.56±0.34 g/L)。三名患者出现了高血压脑病、肾病综合征和快速进展性肾小球肾炎。所有患者的肌酐水平均达到正常水平。ChatGPT 3.5 正确回答了有关 APSGN 的定义、流行病学特征、病理生理机制、诊断和治疗的问题。所有患者都被诊断为 APSGN,临床医生采用的治疗步骤也与 ChatGPT 3.5 的建议相似:ChatGPT 为 APSGN 患者提供的见解和建议是护理和管理患者的宝贵财富。通过人工智能应用,临床医生可以审查治疗决策并制定更有效的治疗计划。
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来源期刊
Medeniyet medical journal
Medeniyet medical journal Medicine-Medicine (all)
CiteScore
1.70
自引率
0.00%
发文量
88
审稿时长
5 weeks
期刊介绍: The Medeniyet Medical Journal (Medeniyet Med J) is an open access, peer-reviewed, and scientific journal of Istanbul Medeniyet University Faculty of Medicine on various academic disciplines in medicine, which is published in English four times a year, in March, June, September, and December by a group of academics. Medeniyet Medical Journal is the continuation of Göztepe Medical Journal (ISSN: 1300-526X) which was started publishing in 1985. It changed the name as Medeniyet Medical Journal in 2015. Submission and publication are free of charge. No fees are asked from the authors for evaluation or publication process. All published articles are available online in the journal website (www.medeniyetmedicaljournal.org) without any fee. The journal publishes intradisciplinary or interdisciplinary clinical, experimental, and basic researches as well as original case reports, reviews, invited reviews, or letters to the editor, Being published since 1985, the Medeniyet Med J recognizes that the best science should lead to better lives based on the fact that the medicine should serve to the needs of society, and knowledge should transform society. The journal aims to address current issues at both national and international levels, start debates, and exert an influence on decision-makers all over the world by integrating science in everyday life. Medeniyet Med J is committed to serve the public and influence people’s lives in a positive way by making science widely accessible. Believing that the only goal is improving lives, and research has an impact on people’s lives, we select the best research papers in line with this goal.
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