Ran Atzmon, Jeremy Dubin, Shai Shemesh, Eran Tamir, Eyal Yaacobi, Ezequiel Palmanovich, Michael Drexler, Nissim Ohana
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引用次数: 0
Abstract
Objectives: This study examines the impact of pulmonary embolism (PE) on mortality among patients with femoral neck fractures, exploring the predictive value of preoperative PE for postoperative occurrences and associated mortality over a 5-year follow-up period.
Methods: We analyzed 2256 patients over 60 years old admitted with femoral neck fractures, focusing on those who developed DVT or PE postoperatively. Surgical intervention aimed within 48 hours without pharmacological thromboprophylaxis, utilizing mechanical prophylaxis instead. Postoperative management included Enoxaparin administration. Data analysis employed SPSS 21, with chi-squared tests, T-tests, and multivariate logistic regression to explore mortality and PE incidence.
Results: PE was diagnosed in 1.4% of patients, with a notable mortality contrast between patients with PE (87%) and those without (59.7%) over 5 years. A history of preoperative PE emerged as a significant risk factor for postoperative PE. Despite surgical variations, no significant correlation was found between surgery type and PE incidence. Early postoperative weight-bearing and institutional rehabilitation did not significantly alter PE incidence rates.
Conclusions: The study underscores the significant mortality risk associated with preoperative PE in femoral neck fracture patients. It highlights the necessity for vigilant PE risk assessment and management, challenging assumptions about the protective role of early mobility and rehabilitation in PE incidence. Further research is essential to refine patient care strategies and improve outcomes.
目的:本研究探讨了肺栓塞(PE)对股骨颈骨折患者死亡率的影响:本研究探讨了肺栓塞(PE)对股骨颈骨折患者死亡率的影响,探索了术前肺栓塞对术后发生率和随访 5 年的相关死亡率的预测价值:我们分析了 2256 名 60 岁以上股骨颈骨折患者,重点关注术后发生深静脉血栓或 PE 的患者。手术干预的目标是在48小时内完成,不使用药物血栓预防,而是使用机械预防。术后管理包括使用依诺肝素。数据分析采用SPSS 21,通过卡方检验、T检验和多变量逻辑回归来探讨死亡率和PE发生率:结果:1.4%的患者确诊为 PE,5 年内有 PE(87%)和无 PE(59.7%)的患者死亡率对比明显。术前有 PE 病史是导致术后 PE 的重要风险因素。尽管手术方式不同,但手术类型与 PE 发生率之间并无明显关联。术后早期负重和住院康复并不能明显改变 PE 的发生率:本研究强调了股骨颈骨折患者术前PE所带来的巨大死亡风险。结论:该研究强调了股骨颈骨折患者术前PE所带来的巨大死亡风险,强调了警惕PE风险评估和管理的必要性,并对早期活动和康复对PE发生率的保护作用这一假设提出了质疑。进一步的研究对完善患者护理策略和改善预后至关重要。
期刊介绍:
Geriatric Orthopaedic Surgery & Rehabilitation (GOS) is an open access, peer-reviewed journal that provides clinical information concerning musculoskeletal conditions affecting the aging population. GOS focuses on care of geriatric orthopaedic patients and their subsequent rehabilitation. This journal is a member of the Committee on Publication Ethics (COPE).