Filum terminale infected epidermoid cysts in pediatric age group; A case series

Q1 Medicine World Neurosurgery: X Pub Date : 2024-10-01 DOI:10.1016/j.wnsx.2024.100408
Walid A. Abdel Ghany , Iman H. Hewedi , George Halim , Mostafa G. Mahran , Sahar Talaat , Dina Amin Saleh , Mazen T. Al Karras , Mohamed E. Elhawi , Mohamed Ashraf Mahmoud , Marwa A. Nassef , Aly Ibrahim
{"title":"Filum terminale infected epidermoid cysts in pediatric age group; A case series","authors":"Walid A. Abdel Ghany ,&nbsp;Iman H. Hewedi ,&nbsp;George Halim ,&nbsp;Mostafa G. Mahran ,&nbsp;Sahar Talaat ,&nbsp;Dina Amin Saleh ,&nbsp;Mazen T. Al Karras ,&nbsp;Mohamed E. Elhawi ,&nbsp;Mohamed Ashraf Mahmoud ,&nbsp;Marwa A. Nassef ,&nbsp;Aly Ibrahim","doi":"10.1016/j.wnsx.2024.100408","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Epidermoid cysts are rare and account for only 1 % of primary spinal tumors. It's due to inclusion of ectodermal tissue during the third and fourth weeks of gestation. Infected epidermoid cysts are exceedingly rare with very few reports in literature. The clinical presentations include radicular symptoms, motor weakness, sphincteric disturbance, and repeated chemical meningitis. Surgery of this kind of tumor remained a challenge and of a considerable recurrence rate.</div></div><div><h3>Methods</h3><div>This is a retrospective study reviewing the records of six children who were treated for filum terminale infected epidermoid cysts. All patients underwent microsurgery, and the surgical outcomes were studied through a follow up period of at least 24 months.</div></div><div><h3>Results</h3><div>All children had a low back dermal sinus with purulent discharge. One child was a recurrent presentation after the previous two surgeries for evacuation of pus collection, and the other five children were operated for the first time. All the six children had an associated neurological deficit; one child presented with active central nervous system infection, and one child had a history of meningitis and admission to hospital prior to our surgery. Regular follow up revealed no recurrence in any of the six patients. The five patients, who presented with motor weakness, showed significant improvement of the motor power with regular post-operative physical therapy.</div></div><div><h3>Conclusion</h3><div>Epidermoid cysts are rare benign lesions that may lead to significant morbidity when infected. The aim of microsurgical excision is to remove the cyst content and its capsule without inducing or increasing neurological deficit by the aid of intraoperative neuromonitoring and microsurgery techniques.</div></div>","PeriodicalId":37134,"journal":{"name":"World Neurosurgery: X","volume":"24 ","pages":"Article 100408"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Neurosurgery: X","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S259013972400139X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Background

Epidermoid cysts are rare and account for only 1 % of primary spinal tumors. It's due to inclusion of ectodermal tissue during the third and fourth weeks of gestation. Infected epidermoid cysts are exceedingly rare with very few reports in literature. The clinical presentations include radicular symptoms, motor weakness, sphincteric disturbance, and repeated chemical meningitis. Surgery of this kind of tumor remained a challenge and of a considerable recurrence rate.

Methods

This is a retrospective study reviewing the records of six children who were treated for filum terminale infected epidermoid cysts. All patients underwent microsurgery, and the surgical outcomes were studied through a follow up period of at least 24 months.

Results

All children had a low back dermal sinus with purulent discharge. One child was a recurrent presentation after the previous two surgeries for evacuation of pus collection, and the other five children were operated for the first time. All the six children had an associated neurological deficit; one child presented with active central nervous system infection, and one child had a history of meningitis and admission to hospital prior to our surgery. Regular follow up revealed no recurrence in any of the six patients. The five patients, who presented with motor weakness, showed significant improvement of the motor power with regular post-operative physical therapy.

Conclusion

Epidermoid cysts are rare benign lesions that may lead to significant morbidity when infected. The aim of microsurgical excision is to remove the cyst content and its capsule without inducing or increasing neurological deficit by the aid of intraoperative neuromonitoring and microsurgery techniques.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
儿科终末丝状感染性表皮样囊肿:一个病例系列
背景表皮样囊肿非常罕见,仅占原发性脊柱肿瘤的 1%。它是由于妊娠第三和四周时外胚层组织包裹所致。感染性表皮样囊肿极为罕见,文献报道极少。临床表现包括根性症状、运动无力、括约肌障碍和反复化学性脑膜炎。这种肿瘤的手术治疗仍然是一项挑战,而且复发率相当高。方法这是一项回顾性研究,回顾了六名儿童的记录,他们都曾接受过丝状终末感染性表皮样囊肿的治疗。所有患者均接受了显微外科手术,并通过至少 24 个月的随访研究了手术效果。其中一名患儿是在前两次手术排出脓液后复发的,另外五名患儿是首次手术。所有六名患儿均伴有神经功能缺损;其中一名患儿伴有活动性中枢神经系统感染,一名患儿在手术前曾患脑膜炎并入院治疗。定期随访显示,六名患者均未复发。结论表皮样囊肿是一种罕见的良性病变,一旦感染可能会导致严重的发病率。显微外科切除术的目的是借助术中神经监测和显微外科技术,在不诱发或加重神经功能缺损的情况下切除囊肿内容物及其囊膜。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
World Neurosurgery: X
World Neurosurgery: X Medicine-Surgery
CiteScore
3.10
自引率
0.00%
发文量
23
审稿时长
44 days
期刊最新文献
Vitamin D deficiency and intracranial aneurysms: Systematic Review Editorial Board Filum terminale infected epidermoid cysts in pediatric age group; A case series Return to play following craniotomy for non-traumatic brain lesions Determining prognostic factors in the treatment of primary hemifacial spasm: Clinical outcomes and complications. A literature review
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1