Characteristics and Presentation of Orthostatic Hypertension in Community-Dwelling Older Adults

Abstract

Background Standing poses a hemodynamic challenge for the cardiovascular system, regulated by neurohumoral reflexes. In 2023, an elevated blood pressure response upon standing was officially defined as a minimum 20 mmHg increase in systolic pressure during position changes, distinguishing Orthostatic Hypertension (OHT) as a condition where blood pressure exceeds 140 mmHg when standing. This new definition underscores the importance of understanding the implications of OHT on individuals' health and quality of life. Methods Retrospective study of the Technology Research for Independent Living (TRIL) Clinic at St. James’s Hospital, from August 2007 to May 2009. The population included healthy community-dwelling adults aged 60 and older. This study aimed to profile individuals with OHT, understand the predictors of this condition, and explore its association with biopsychosocial variables. Results In a study of 442 participants (67.7% female, mean age 72.7), we identified a prevalence rate of 12.9% for an exaggerated orthostatic pressor response and observed OHT in 6.1% of participants at the 120-second mark after standing. Additionally, significant associations were discovered between OHT and conditions such as heart failure, stroke, and the use of certain medications such as SSRI and ACE inhibitors. Conclusion The results of this study highlight the potential health consequences of OHT among older adults, particularly in those with pre-existing cardiovascular conditions. Further research is needed to explore this lesser-known but significant orthostatic disorder.