Megan Hetherington-Rauth,Tyler A Mansfield,Leon Lenchik,Ashley A Weaver,Deborah M Kado,Nancy E Lane,Eric Orwoll,Peggy M Cawthon
BACKGROUNDMachine learning applied to computed tomography (CT) images captures variations in skeletal muscle texture and structure not detectable by conventional measures. These novel 'radiomic' features may offer added value in predicting muscle function and physical performance beyond traditional CT-derived muscle area and density. We aimed to identify radiomic features of skeletal muscle associated with grip strength, leg power and walking speed in older men.METHODSIn the Osteoporotic Fractures in Men study (n = 3404; 73.8 ± 5.9 years), participants underwent baseline CT scans (trunk L1, L3; right and left thigh) and assessments of grip strength, 6 m walk and leg power (Nottingham Power Rig). Muscle area and density were derived from automatically segmented CT images. Radiomic features were extracted using PyRadiomics. Elastic net regression and factor analysis identified key radiomic features; associations with muscle function/performance were assessed using regression models.RESULTSFactor analysis identified nine factors for Trunk-L1 and eight for the other regions. Trunk-based factors significantly improved model fit for leg power, grip strength and walking speed (P < .05). Factor 1, representing body size and muscle texture complexity, was the most consistent predictor across outcomes. The Gray-Level Co-occurrence Matrix feature 'cluster prominence' was inversely associated with walking speed (β = -0.06 at L1; -0.05 at L3) and leg power (β = -0.05 at L1), independent of age, height, weight, muscle CSA, muscle density and technical group.CONCLUSIONCT-derived radiomic features in the trunk region may reflect skeletal muscle structural characteristics that independently relate to strength, power and mobility in older men.
{"title":"Association of radiomic features of skeletal muscle on CT images with muscle function and physical performance in older men.","authors":"Megan Hetherington-Rauth,Tyler A Mansfield,Leon Lenchik,Ashley A Weaver,Deborah M Kado,Nancy E Lane,Eric Orwoll,Peggy M Cawthon","doi":"10.1093/ageing/afag057","DOIUrl":"https://doi.org/10.1093/ageing/afag057","url":null,"abstract":"BACKGROUNDMachine learning applied to computed tomography (CT) images captures variations in skeletal muscle texture and structure not detectable by conventional measures. These novel 'radiomic' features may offer added value in predicting muscle function and physical performance beyond traditional CT-derived muscle area and density. We aimed to identify radiomic features of skeletal muscle associated with grip strength, leg power and walking speed in older men.METHODSIn the Osteoporotic Fractures in Men study (n = 3404; 73.8 ± 5.9 years), participants underwent baseline CT scans (trunk L1, L3; right and left thigh) and assessments of grip strength, 6 m walk and leg power (Nottingham Power Rig). Muscle area and density were derived from automatically segmented CT images. Radiomic features were extracted using PyRadiomics. Elastic net regression and factor analysis identified key radiomic features; associations with muscle function/performance were assessed using regression models.RESULTSFactor analysis identified nine factors for Trunk-L1 and eight for the other regions. Trunk-based factors significantly improved model fit for leg power, grip strength and walking speed (P < .05). Factor 1, representing body size and muscle texture complexity, was the most consistent predictor across outcomes. The Gray-Level Co-occurrence Matrix feature 'cluster prominence' was inversely associated with walking speed (β = -0.06 at L1; -0.05 at L3) and leg power (β = -0.05 at L1), independent of age, height, weight, muscle CSA, muscle density and technical group.CONCLUSIONCT-derived radiomic features in the trunk region may reflect skeletal muscle structural characteristics that independently relate to strength, power and mobility in older men.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"409 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147471737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma Walker,Fen Wu,Andrew G Rundle,Simin Hua,James W Quinn,Kathryn M Neckerman,Yelena Afanasyeva,Alan A Arslan,Karen L Koenig,Anne Zeleniuch-Jacquotte,Yu Chen
BACKGROUNDThe role of modifiable environmental factors in Alzheimer's disease (AD) risk remains poorly understood. Built environment features such as neighbourhood walkability (NW) may influence long-term cognitive health among women.METHODSThe New York University Women's Health Study recruited 14 273 cognitively healthy women aged 35-65 years between 1985 and 1991, with follow-up for over 30 years. We geocoded residential addresses for each participant to derive a validated four-item baseline NW measure and a two-item average annual NW index over the follow-up period. We conducted a nested case-control study of 1865 AD cases identified via linkage to Medicare claims during follow-up matched to 3730 controls on age, race/ethnicity and Medicare coverage using risk-set sampling. We used conditional logistic regression to estimate odds ratios (ORs) and 95% confidence intervals for AD in relation to tertiles of NW measures, adjusting for potential confounders. Subgroup analyses examined potential effect modification.RESULTSCompared with women living in areas with the lowest baseline NW, those in the middle and highest tertiles had lower odds of having a diagnosis of AD during follow-up, with an OR of 0.95 (0.82-1.11) and 0.83 (0.71-0.98), respectively (P-trend = .03). Results were similar when using average annual NW. The association did not differ appreciably by age, smoking status, education or body mass index.CONCLUSIONSHigher midlife NW was associated with reduced odds of AD later in life. These findings highlight the potential for built environment interventions to promote cognitive health and support healthy ageing in women.
{"title":"The association between midlife neighbourhood walkability and Alzheimer's disease in women: a prospective nested case-control study.","authors":"Emma Walker,Fen Wu,Andrew G Rundle,Simin Hua,James W Quinn,Kathryn M Neckerman,Yelena Afanasyeva,Alan A Arslan,Karen L Koenig,Anne Zeleniuch-Jacquotte,Yu Chen","doi":"10.1093/ageing/afag054","DOIUrl":"https://doi.org/10.1093/ageing/afag054","url":null,"abstract":"BACKGROUNDThe role of modifiable environmental factors in Alzheimer's disease (AD) risk remains poorly understood. Built environment features such as neighbourhood walkability (NW) may influence long-term cognitive health among women.METHODSThe New York University Women's Health Study recruited 14 273 cognitively healthy women aged 35-65 years between 1985 and 1991, with follow-up for over 30 years. We geocoded residential addresses for each participant to derive a validated four-item baseline NW measure and a two-item average annual NW index over the follow-up period. We conducted a nested case-control study of 1865 AD cases identified via linkage to Medicare claims during follow-up matched to 3730 controls on age, race/ethnicity and Medicare coverage using risk-set sampling. We used conditional logistic regression to estimate odds ratios (ORs) and 95% confidence intervals for AD in relation to tertiles of NW measures, adjusting for potential confounders. Subgroup analyses examined potential effect modification.RESULTSCompared with women living in areas with the lowest baseline NW, those in the middle and highest tertiles had lower odds of having a diagnosis of AD during follow-up, with an OR of 0.95 (0.82-1.11) and 0.83 (0.71-0.98), respectively (P-trend = .03). Results were similar when using average annual NW. The association did not differ appreciably by age, smoking status, education or body mass index.CONCLUSIONSHigher midlife NW was associated with reduced odds of AD later in life. These findings highlight the potential for built environment interventions to promote cognitive health and support healthy ageing in women.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"271 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147495216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Home-based extended rehabilitation for older people with frailty (HERO): a randomised controlled trial.","authors":"","doi":"10.1093/ageing/afag069","DOIUrl":"https://doi.org/10.1093/ageing/afag069","url":null,"abstract":"","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"1 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147465369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ageing, advanced kidney disease and the limits of prediction: what AGNES tells us about decision-making.","authors":"John Holland","doi":"10.1093/ageing/afag059","DOIUrl":"https://doi.org/10.1093/ageing/afag059","url":null,"abstract":"","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"6 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147471788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editor's view-the pathophysiology of delirium.","authors":"Roy L Soiza","doi":"10.1093/ageing/afag055","DOIUrl":"https://doi.org/10.1093/ageing/afag055","url":null,"abstract":"","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"55 3","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147466624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Menelaos M Dimitriadis,Kitty J Kokkeler,Emiel O Hoogendijk,Radboud M Marijnissen,Ivan Aprahamian,Hans W Jeuring,R C Oude Voshaar
BACKGROUNDAdverse childhood experiences (ACEs), known to increase lifelong health risks, have recently been linked to frailty. This study examined whether ACEs predict the onset and progression of sarcopenia, a core component of the frailty phenotype.METHODSWe analysed 23 476 participants aged 45-85 years in the Canadian Longitudinal Study on Aging with 3-year follow-up (49.5% female; mean age 62.1 ± 9.9). Eight ACEs were assessed using validated retrospective instruments. Associations between ACE count and incident sarcopenia (revised European Working groups on Sarcopenia in Older People criteria) were evaluated using multivariable logistic regression, while changes in continuous sarcopenia components were assessed with lagged linear models adjusted for age, sex and ethnicity. Moderating effects of age, sex, ethnicity, depression (CESD ≥ 10) and socioeconomic position (education, income) were explored.RESULTSOverall, 12.7% of participants reported a high ACE burden (≥3). Among 21 910 participants without baseline sarcopenia, 614 (2.8%) developed sarcopenia. Depression, but not sociodemographic factors, moderated the ACE-sarcopenia association. ACE count predicted incident sarcopenia among depressed participants [OR (odds ratio) = 1.10 (95% (confidence interval) CI: 1.02-1.20), P = .016], but not among nondepressed participants [OR = 0.98 (95% CI: 0.93-1.03), P = .399]. Depression also moderated ACE-related declines in lean muscle mass and handgrip strength. Post hoc analyses showed that ACE-related worsening of chair rise performance and gait speed was mediated by depression.CONCLUSIONSACEs are associated with modest declines in muscle mass and function, with depression emerging as a key pathway linking early adversity to later-life sarcopenia. These findings highlight the need to integrate psychosocial history and mental health into risk stratification and preventive strategies for functional decline.
众所周知，不良的童年经历（ace）会增加终身健康风险，最近发现它与身体虚弱有关。这项研究考察了ace是否能预测肌少症的发病和进展，肌少症是虚弱表型的一个核心组成部分。方法我们对加拿大老龄化纵向研究的23476名年龄在45-85岁之间的参与者进行了3年随访，其中女性49.5%，平均年龄62.1±9.9岁。使用经过验证的回顾性仪器评估8例ace。ACE计数与肌少症发生率之间的关系（修订后的欧洲老年人肌少症工作组标准）采用多变量logistic回归进行评估，而连续肌少症成分的变化采用年龄、性别和种族调整后的滞后线性模型进行评估。探讨年龄、性别、种族、抑郁（CESD≥10）和社会经济地位（教育、收入）的调节作用。总体而言，12.7%的参与者报告了高ACE负担（≥3）。在21 910名没有基线肌少症的参与者中，614名（2.8%）出现了肌少症。抑郁症，而不是社会人口因素，缓和了ace -肌肉减少症的关联。ACE计数预测抑郁症患者肌肉减少症的发生[OR（优势比）= 1.10(95%（置信区间）CI: 1.02-1.20), P =。[016]，但在非抑郁参与者中没有[OR = 0.98 (95% CI: 0.93-1.03), P = .399]。抑郁也能减缓ace相关的瘦肌肉量和握力的下降。事后分析显示，ace相关的椅子起身性能和步态速度恶化是由抑郁介导的。结论：sace与肌肉质量和功能的适度下降有关，抑郁症是将早期逆境与晚年肌肉减少症联系起来的关键途径。这些发现强调了将社会心理病史和心理健康纳入功能衰退的风险分层和预防策略的必要性。
{"title":"Adverse childhood experiences and sarcopenia: a prospective study embedded in the Canadian Longitudinal Study on Aging.","authors":"Menelaos M Dimitriadis,Kitty J Kokkeler,Emiel O Hoogendijk,Radboud M Marijnissen,Ivan Aprahamian,Hans W Jeuring,R C Oude Voshaar","doi":"10.1093/ageing/afag050","DOIUrl":"https://doi.org/10.1093/ageing/afag050","url":null,"abstract":"BACKGROUNDAdverse childhood experiences (ACEs), known to increase lifelong health risks, have recently been linked to frailty. This study examined whether ACEs predict the onset and progression of sarcopenia, a core component of the frailty phenotype.METHODSWe analysed 23 476 participants aged 45-85 years in the Canadian Longitudinal Study on Aging with 3-year follow-up (49.5% female; mean age 62.1 ± 9.9). Eight ACEs were assessed using validated retrospective instruments. Associations between ACE count and incident sarcopenia (revised European Working groups on Sarcopenia in Older People criteria) were evaluated using multivariable logistic regression, while changes in continuous sarcopenia components were assessed with lagged linear models adjusted for age, sex and ethnicity. Moderating effects of age, sex, ethnicity, depression (CESD ≥ 10) and socioeconomic position (education, income) were explored.RESULTSOverall, 12.7% of participants reported a high ACE burden (≥3). Among 21 910 participants without baseline sarcopenia, 614 (2.8%) developed sarcopenia. Depression, but not sociodemographic factors, moderated the ACE-sarcopenia association. ACE count predicted incident sarcopenia among depressed participants [OR (odds ratio) = 1.10 (95% (confidence interval) CI: 1.02-1.20), P = .016], but not among nondepressed participants [OR = 0.98 (95% CI: 0.93-1.03), P = .399]. Depression also moderated ACE-related declines in lean muscle mass and handgrip strength. Post hoc analyses showed that ACE-related worsening of chair rise performance and gait speed was mediated by depression.CONCLUSIONSACEs are associated with modest declines in muscle mass and function, with depression emerging as a key pathway linking early adversity to later-life sarcopenia. These findings highlight the need to integrate psychosocial history and mental health into risk stratification and preventive strategies for functional decline.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"10 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147465368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olivia J Russell,Kamar E Ameen-Ali,Angela C Flynn,Sarah Barnes,Jennifer Ferguson,Andrew Divers,Dorothy Newbury-Birch,Judith Eberhardt,John S Young,Mani Santhana Krishnan,Ahmad A Khundakar
Delirium is a common but frequently under-recognised neuropsychiatric syndrome in care homes, especially among residents living with dementia. Delirium is associated with substantial morbidity, mortality and preventable healthcare complications, yet evidence on how it is recognised and managed in residential care remains limited. This qualitative study explored care home managers' perspectives on delirium care within privately owned care homes in a region of England, UK, and data analysed thematically to identify key challenges and opportunities for improvement. Three overarching themes were identified: (1) Recognising and Responding to Delirium described how detection often relied on staff familiarity with residents' usual behaviour, with limited use of formal assessment tools and frequent difficulty distinguishing delirium from dementia, particularly in hypoactive presentations.(2) Systemic Barriers to Quality Care highlighted the impact of chronic underfunding, fragmented communication at hospital discharge, unclear clinical responsibility and limited access to training and clinical support.(3) Collaborative Care and Support Networks captured the role of families and external professionals in delirium management, with variable communication, inconsistent validation of care home concerns and challenges coordinating care across services. In response to these challenges, we recommend co-produced delirium education for care staff, clearer clinical pathways and stronger interprofessional collaboration to ensure that delirium is recognised and treated as a potentially life-threatening medical emergency.
{"title":"'Just a delirium': a qualitative study of care home managers' perspectives on barriers to delirium recognition and management in UK care homes.","authors":"Olivia J Russell,Kamar E Ameen-Ali,Angela C Flynn,Sarah Barnes,Jennifer Ferguson,Andrew Divers,Dorothy Newbury-Birch,Judith Eberhardt,John S Young,Mani Santhana Krishnan,Ahmad A Khundakar","doi":"10.1093/ageing/afag056","DOIUrl":"https://doi.org/10.1093/ageing/afag056","url":null,"abstract":"Delirium is a common but frequently under-recognised neuropsychiatric syndrome in care homes, especially among residents living with dementia. Delirium is associated with substantial morbidity, mortality and preventable healthcare complications, yet evidence on how it is recognised and managed in residential care remains limited. This qualitative study explored care home managers' perspectives on delirium care within privately owned care homes in a region of England, UK, and data analysed thematically to identify key challenges and opportunities for improvement. Three overarching themes were identified: (1) Recognising and Responding to Delirium described how detection often relied on staff familiarity with residents' usual behaviour, with limited use of formal assessment tools and frequent difficulty distinguishing delirium from dementia, particularly in hypoactive presentations.(2) Systemic Barriers to Quality Care highlighted the impact of chronic underfunding, fragmented communication at hospital discharge, unclear clinical responsibility and limited access to training and clinical support.(3) Collaborative Care and Support Networks captured the role of families and external professionals in delirium management, with variable communication, inconsistent validation of care home concerns and challenges coordinating care across services. In response to these challenges, we recommend co-produced delirium education for care staff, clearer clinical pathways and stronger interprofessional collaboration to ensure that delirium is recognised and treated as a potentially life-threatening medical emergency.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"88 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147471785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUNDThis study aimed to estimate the risk of four adverse outcomes [disability in instrumental activities of daily living (IADL), institutionalisation, dementia and death] associated with Intrinsic Capacity (IC) impairment at baseline, and to test different combinations of IC impairments to better identify high-risk profiles.METHODSThe sample was drawn from two population-based cohorts (Three-City and AMI), in which the six IC domains were assessed: cognition, nutrition, psychology, hearing, vision and mobility. Participants were categorised into three groups: no impairment (IC0), single impairment (IC1) and two impairments or more (IC2+). Cox models were used to estimate the risk of adverse outcomes associated with IC1 and IC2+ compared to IC0. Conditional inference tree analyses, followed by Cox models, were then conducted to identify the most predictive domains and combinations defining the highest-risk profiles.RESULTSAmong the 2964 participants ≥65 included, 24.9% had one IC impairment and 62.3% had two or more. Being in the IC2+ group was associated with a significantly increased risk of all outcomes [adjusted hazard ratios (aHRs) ranging from 2.0 to 3.0], whereas IC1 was not, except for IADL-disability (aHR = 1.46; 95%CI = 1.14-1.87). Mobility, cognitive and visual impairments were constitutive of the highest-risk profiles.CONCLUSIONSThis study supports the relevance of the ICOPE-targeted IC domains in predicting adverse outcomes. Given the high proportion of individuals screened positive, refining the screening threshold by considering the number and combination of impairments may better identify those who should benefit from the subsequent steps for more advanced assessment or intervention as a priority.
{"title":"Improving screening in the WHO ICOPE strategy: lessons from risk profiles for major adverse health outcomes.","authors":"Karine Pérès,Ivane Koumetio Jiatsa,Antoine Gbessemehlan,Jeanne Bardinet,Catherine Helmer,Achille Tchalla,Luc Letenneur","doi":"10.1093/ageing/afag051","DOIUrl":"https://doi.org/10.1093/ageing/afag051","url":null,"abstract":"BACKGROUNDThis study aimed to estimate the risk of four adverse outcomes [disability in instrumental activities of daily living (IADL), institutionalisation, dementia and death] associated with Intrinsic Capacity (IC) impairment at baseline, and to test different combinations of IC impairments to better identify high-risk profiles.METHODSThe sample was drawn from two population-based cohorts (Three-City and AMI), in which the six IC domains were assessed: cognition, nutrition, psychology, hearing, vision and mobility. Participants were categorised into three groups: no impairment (IC0), single impairment (IC1) and two impairments or more (IC2+). Cox models were used to estimate the risk of adverse outcomes associated with IC1 and IC2+ compared to IC0. Conditional inference tree analyses, followed by Cox models, were then conducted to identify the most predictive domains and combinations defining the highest-risk profiles.RESULTSAmong the 2964 participants ≥65 included, 24.9% had one IC impairment and 62.3% had two or more. Being in the IC2+ group was associated with a significantly increased risk of all outcomes [adjusted hazard ratios (aHRs) ranging from 2.0 to 3.0], whereas IC1 was not, except for IADL-disability (aHR = 1.46; 95%CI = 1.14-1.87). Mobility, cognitive and visual impairments were constitutive of the highest-risk profiles.CONCLUSIONSThis study supports the relevance of the ICOPE-targeted IC domains in predicting adverse outcomes. Given the high proportion of individuals screened positive, refining the screening threshold by considering the number and combination of impairments may better identify those who should benefit from the subsequent steps for more advanced assessment or intervention as a priority.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"6 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147471684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: The World Health Organization ageism towards older persons scale: preliminary validation of a novel measure of ageist stereotypes, prejudices, and discrimination in four different countries.","authors":"","doi":"10.1093/ageing/afag067","DOIUrl":"https://doi.org/10.1093/ageing/afag067","url":null,"abstract":"","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"55 3","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147466677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUNDFalls among older adults in nursing homes are frequent and have serious consequences. They represent a major public health issue with significant costs.OBJECTIVETo investigate the cost-effectiveness of a gerontological telemedicine programme in preventing falls among residents of nursing homes located in areas with limited access to primary care ('medical deserts').DESIGNGERONTACCESS was a prospective, longitudinal, randomised study. In this secondary analysis of that trial, 426 residents aged ≥60 years living in a nursing home located in a medical desert were included in an intervention group (IG) (participants in a preventive gerontological telemedicine programme) or a control group (CG) (those who received usual care). Data were collected between July 2016 and January 2018.MAIN OUTCOME MEASURESThe study outcomes were the proportion of patients who experienced falls during the 1-year study period. The Incremental Cost Effectiveness Ratio was calculated. Data on each fall were collected every month. Direct costs were assessed following guidelines from the French National Authority for Health.RESULTSOver 1 year, 1086 falls were recorded, with no significant difference in total falls between the two groups. However, 980 non-serious falls (those that did not require medical assistance) were observed, involving 107 residents in the IG versus 134 residents in the CG (P = .006). Significantly fewer residents in the IG experienced at least one fall compared to the CG (P = .02). The cost analysis indicated that each fall avoided in the IG saved ~US$4272.CONCLUSIONSThe gerontological telemedicine programme, is a cost-effective way to reduce the number of non-serious falls among residents. It maybe also delayed the timing of the first fall.
{"title":"A person-centred ehealth intervention for fall prevention in nursing homes lacking geriatric expertise: cost-effectiveness analysis within a randomised controlled trial.","authors":"Caroline Gayot,Noëlle Cardinaud,Kévin Zarca,Isabelle Zaleski,Cécile Laubarie-Mouret,Achille Edem Tchalla","doi":"10.1093/ageing/afag053","DOIUrl":"https://doi.org/10.1093/ageing/afag053","url":null,"abstract":"BACKGROUNDFalls among older adults in nursing homes are frequent and have serious consequences. They represent a major public health issue with significant costs.OBJECTIVETo investigate the cost-effectiveness of a gerontological telemedicine programme in preventing falls among residents of nursing homes located in areas with limited access to primary care ('medical deserts').DESIGNGERONTACCESS was a prospective, longitudinal, randomised study. In this secondary analysis of that trial, 426 residents aged ≥60 years living in a nursing home located in a medical desert were included in an intervention group (IG) (participants in a preventive gerontological telemedicine programme) or a control group (CG) (those who received usual care). Data were collected between July 2016 and January 2018.MAIN OUTCOME MEASURESThe study outcomes were the proportion of patients who experienced falls during the 1-year study period. The Incremental Cost Effectiveness Ratio was calculated. Data on each fall were collected every month. Direct costs were assessed following guidelines from the French National Authority for Health.RESULTSOver 1 year, 1086 falls were recorded, with no significant difference in total falls between the two groups. However, 980 non-serious falls (those that did not require medical assistance) were observed, involving 107 residents in the IG versus 134 residents in the CG (P = .006). Significantly fewer residents in the IG experienced at least one fall compared to the CG (P = .02). The cost analysis indicated that each fall avoided in the IG saved ~US$4272.CONCLUSIONSThe gerontological telemedicine programme, is a cost-effective way to reduce the number of non-serious falls among residents. It maybe also delayed the timing of the first fall.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"12 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147483731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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