Liver Cancer: Progress and Priorities.

IF 3.7 3区 医学 Q2 ONCOLOGY Cancer Epidemiology Biomarkers & Prevention Pub Date : 2024-10-02 DOI:10.1158/1055-9965.EPI-24-0686
Katherine A McGlynn, Jessica L Petrick, John D Groopman
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Abstract

Liver cancer, the sixth most frequently occurring cancer in the world and the third most common cause of cancer mortality, has wide geographical variation in both incidence and mortality rates. At the end of the 20th century, incidence rates began declining in some high-rate areas and increasing in some lower-rate areas. These trends were undoubtedly driven by the shifting contributions of both well-established and more novel risk factors. While notable strides have been made in combating some major risk factors, such as hepatitis B virus and hepatitis C virus, the emergence of metabolic conditions as important drivers of liver cancer risk indicates that much work remains to be done in prevention. As liver cancer is strongly associated with economic and social deprivation, research, early-diagnosis, and treatment among disadvantaged populations are of paramount importance.

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肝癌:进展与优先事项。
肝癌是世界上发病率第六高的癌症,也是导致癌症死亡的第三大常见病因,其发病率和死亡率的地域差异很大。20 世纪末,一些高发病率地区的发病率开始下降,而一些低发病率地区的发病率则开始上升。毫无疑问,这些趋势是由已确立的风险因素和较新的风险因素共同作用的结果。虽然在应对乙肝病毒和丙肝病毒等一些主要风险因素方面取得了显著进展,但新陈代谢条件成为肝癌风险的重要驱动因素,这表明在预防方面仍有许多工作要做。由于肝癌与经济和社会贫困密切相关,因此对弱势群体进行研究、早期诊断和治疗至关重要。
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来源期刊
Cancer Epidemiology Biomarkers & Prevention
Cancer Epidemiology Biomarkers & Prevention 医学-公共卫生、环境卫生与职业卫生
CiteScore
6.50
自引率
2.60%
发文量
538
审稿时长
1.6 months
期刊介绍: Cancer Epidemiology, Biomarkers & Prevention publishes original peer-reviewed, population-based research on cancer etiology, prevention, surveillance, and survivorship. The following topics are of special interest: descriptive, analytical, and molecular epidemiology; biomarkers including assay development, validation, and application; chemoprevention and other types of prevention research in the context of descriptive and observational studies; the role of behavioral factors in cancer etiology and prevention; survivorship studies; risk factors; implementation science and cancer care delivery; and the science of cancer health disparities. Besides welcoming manuscripts that address individual subjects in any of the relevant disciplines, CEBP editors encourage the submission of manuscripts with a transdisciplinary approach.
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