{"title":"A Novel Rhodamine B Derivative as a \"Turn-on\" Fluorescent Sensor for Cu<sup>2+</sup> with High Selectivity and Sensitivity.","authors":"Li Liu, Tao Zhou, Yawen Li, Tianrong Li","doi":"10.1007/s10895-024-03977-2","DOIUrl":null,"url":null,"abstract":"<p><p>The number of \"turn-on\" fluorescent probes for Cu<sup>2+</sup> is relatively limited, and interference from other metal cations presents a significant challenge for these sensors. In this study, we synthesized and characterized a rhodamine B-based sensor, designated as RBHP, using 1-phenyl-3-methyl-4-benzoyl-5-pyrazolone (PMBP) and rhodamine B hydrazide. Selectivity, sensitivity, solvent effects, water content, and pH of RBHP in relation to Cu²⁺ were conducted. RBHP exhibited an exceptionally low fluorescence background signal in acetonitrile and demonstrated a \"turn-on\" fluorescent response to Cu²⁺. The PMBP-based acylhydrazone moiety and acetonitrile as the detection solvent are crucial for the selective detection. RBHP shows potential as a highly selective and sensitive fluorescent sensor for Cu<sup>2+</sup>.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Fluorescence","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s10895-024-03977-2","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
The number of "turn-on" fluorescent probes for Cu2+ is relatively limited, and interference from other metal cations presents a significant challenge for these sensors. In this study, we synthesized and characterized a rhodamine B-based sensor, designated as RBHP, using 1-phenyl-3-methyl-4-benzoyl-5-pyrazolone (PMBP) and rhodamine B hydrazide. Selectivity, sensitivity, solvent effects, water content, and pH of RBHP in relation to Cu²⁺ were conducted. RBHP exhibited an exceptionally low fluorescence background signal in acetonitrile and demonstrated a "turn-on" fluorescent response to Cu²⁺. The PMBP-based acylhydrazone moiety and acetonitrile as the detection solvent are crucial for the selective detection. RBHP shows potential as a highly selective and sensitive fluorescent sensor for Cu2+.
期刊介绍：
Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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