Filip Świątkowski, Jakub Lambrinow, Tomasz Górnicki, Marta Jurga, Mariusz Chabowski
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引用次数: 0
Abstract
Introduction: Due to the increasing number of cases and the levels of mortality, colorectal cancer is still a major health problem. Therefore, the growing interest in the quality of life of patients and the assessment of the quality of life of patients with colorectal cancer seems to be particularly important. The aim of the study was to investigate and determine factors that have a significant impact on the QoL of patients who were diagnosed with colorectal cancer that was surgically treated in the Surgical Department of the 4th Military Clinical Hospital in Wroclaw.
Methods: 102 respondents were enrolled into the study. The QLQ-C30, QLQ-CR29 as well as an original questionnaire regarding the socioeconomic factors were used for the assessment. The information was supplemented with patients' clinical data.
Results: According to the QLQ-C30 questionnaire the average QoL of the respondents was 55%. Factors such as male gender, younger age, higher BMI, no significant weight loss, living with family, lower level of education and being professionally active have significant positive impact on QoL. In contrary, patients with more advanced and malignant cancer with tumor located in the right half of the colon had worse QoL. The particular domains of QoL influenced by these factors were also identified. Determining these factors will allow for more effective treatment, for the shortening of the hospitalization and finally for the reduction of the costs.
Conclusion: The better QoL of the patients with colorectal cancer treated surgically showed younger men, living with family and with the support from close people, professionally active, with primary level of education, and without significant weight loss, ie less than 5% of body weight in the last 6 months. Moreover, patients with cancer located in the left colon, at a lower stage, with a lower grading demonstrated a better QoL.
导言:由于患病人数和死亡率不断增加,大肠癌仍然是一个重大的健康问题。因此,人们对患者生活质量的关注与日俱增,对结直肠癌患者生活质量的评估显得尤为重要。本研究旨在调查并确定对弗罗茨瓦夫第四军事临床医院外科手术治疗的结直肠癌患者生活质量有重大影响的因素。评估使用了 QLQ-C30、QLQ-CR29 以及有关社会经济因素的原始问卷。患者的临床数据对这些信息进行了补充:根据 QLQ-C30 问卷,受访者的平均 QoL 为 55%。性别为男性、年龄较小、体重指数(BMI)较高、体重无明显减轻、与家人同住、教育程度较低和从事职业活动等因素对 QoL 有显著的积极影响。相反,肿瘤位于结肠右半部的晚期恶性肿瘤患者的 QoL 较差。此外,还确定了受这些因素影响的特定 QoL 领域。确定这些因素将有助于更有效的治疗,缩短住院时间,最终降低费用:通过手术治疗的结直肠癌患者的生活质量较好,这表明这些患者都是年轻男性,与家人生活在一起并得到亲朋好友的支持,从事职业活动,受过初等教育,体重没有明显下降,即在过去 6 个月中体重下降少于 5%。此外,癌症位于左侧结肠、分期较短、分级较低的患者的生活质量也较高。