Pericyte relaxation boosts cerebral blood flow

IF 28.7 1区 医学 Q1 NEUROSCIENCES Nature Reviews Neuroscience Pub Date : 2024-10-02 DOI:10.1038/s41583-024-00873-3
Katherine Whalley
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Abstract

Blocking voltage-gated calcium channels reduces capillary narrowing by pericytes and improves cerebral blood flow in a mouse model of Alzheimer disease.
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毛细血管松弛可促进脑血流
在阿尔茨海默病小鼠模型中,阻断电压门控钙通道可减少周细胞造成的毛细血管狭窄,并改善脑血流量。
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期刊介绍: Nature Reviews Neuroscience is a multidisciplinary journal that covers various fields within neuroscience, aiming to offer a comprehensive understanding of the structure and function of the central nervous system. Advances in molecular, developmental, and cognitive neuroscience, facilitated by powerful experimental techniques and theoretical approaches, have made enduring neurobiological questions more accessible. Nature Reviews Neuroscience serves as a reliable and accessible resource, addressing the breadth and depth of modern neuroscience. It acts as an authoritative and engaging reference for scientists interested in all aspects of neuroscience.
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