Unusual renal involvement during diabetic ketoacidosis (DKA) in a newly diagnosed type I diabetic child.

Acta diabetologica latina Pub Date : 1986-10-01
A Flores d'Arcais, F Meschi, A Sterpa, F Gaboardi, B di Natale, G Chiumello
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Abstract

A 10-year-old boy, in a precomatose state, was admitted to our Endocrine Unit for diabetic ketoacidosis. It took unusually long to reequilibrate the acidosis despite a bicarbonate drip. On the 4th day the patient suddenly complained of an acute abdominal pain associated with macrohematuria and oliguria; ankle edema was evident. No radio-opaque image was detected along the urinary tract. An intravenous pyelogram (IVP) showed an almost totally silent left kidney. Ten days later a control IVP showed complete normality of both kidneys. We postulated that the serious and protracted dehydration might have resulted in the formation of a blood clot along the renal tract and that the rehydration may have subsequently removed it.

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1例新诊断的1型糖尿病患儿糖尿病酮症酸中毒(DKA)期间肾脏异常受累。
一名十岁男童因糖尿病酮症酸中毒而进入内分泌科,处于昏迷状态。尽管滴下了碳酸氢盐,但重新平衡酸中毒还是花了很长时间。第4天,患者突然主诉急性腹痛并伴有大量血尿和少尿;踝关节明显水肿。尿路未见放射性不透明图像。静脉肾盂造影(IVP)显示左肾几乎完全沉默。10天后对照IVP显示双肾完全正常。我们推测,严重和持久的脱水可能导致沿肾道形成血凝块,随后补液可能将其清除。
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Pharmacological comparison between tolbutamide and two second generation hypoglycemic sulfonylureas (Glibenclamide and glisoxepide) Unusual renal involvement during diabetic ketoacidosis (DKA) in a newly diagnosed type I diabetic child. Effect of treatment with insulin or diet on intermediary metabolites in pregnant women with chemical diabetes in the third trimester of pregnancy. Psycho-social problems of diabetic children and adolescents. Increased LDL cholesterol in non-insulin-dependent diabetics with maculopathy.
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