Tiffany Lau, Anirban Dutta, Prashant J Purohit, Karen Thompson, Kara Yamamoto, Andrew Feng, Timothy Beaty, Marian Melish, Bryscen Prothero, David Kurahara, Brian Wu, Edward Fong, Rodolfo E Bégué
{"title":"A Child with COVID-19 Complicated by Rapidly Progressive Severe Organizing Pneumonia: A Case Report.","authors":"Tiffany Lau, Anirban Dutta, Prashant J Purohit, Karen Thompson, Kara Yamamoto, Andrew Feng, Timothy Beaty, Marian Melish, Bryscen Prothero, David Kurahara, Brian Wu, Edward Fong, Rodolfo E Bégué","doi":"10.62547/XGJS9690","DOIUrl":null,"url":null,"abstract":"<p><p>A 2-year-old boy tested positive for SARS-CoV-2 and, after 30 days of mild-moderate respiratory symptoms, suddenly deteriorated and required extracorporeal membrane oxygenation. Lung biopsy was performed with findings consistent with organizing pneumonia. He received intensive therapy with high-dose methylprednisolone, intravenous immune globulin, rituximab, and plasmapheresis without improvement. He died after 85 days hospitalization. This case highlights unique presentations of COVID-19 and reaffirms the concept that, while rare in Hawai'i, pediatric COVID-19 is an ongoing problem and that severe, even fatal, disease can occur.</p>","PeriodicalId":36659,"journal":{"name":"Hawai''i journal of health & social welfare","volume":"83 10","pages":"274-278"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450319/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hawai''i journal of health & social welfare","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.62547/XGJS9690","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
A 2-year-old boy tested positive for SARS-CoV-2 and, after 30 days of mild-moderate respiratory symptoms, suddenly deteriorated and required extracorporeal membrane oxygenation. Lung biopsy was performed with findings consistent with organizing pneumonia. He received intensive therapy with high-dose methylprednisolone, intravenous immune globulin, rituximab, and plasmapheresis without improvement. He died after 85 days hospitalization. This case highlights unique presentations of COVID-19 and reaffirms the concept that, while rare in Hawai'i, pediatric COVID-19 is an ongoing problem and that severe, even fatal, disease can occur.