A Child with COVID-19 Complicated by Rapidly Progressive Severe Organizing Pneumonia: A Case Report.

Tiffany Lau, Anirban Dutta, Prashant J Purohit, Karen Thompson, Kara Yamamoto, Andrew Feng, Timothy Beaty, Marian Melish, Bryscen Prothero, David Kurahara, Brian Wu, Edward Fong, Rodolfo E Bégué
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Abstract

A 2-year-old boy tested positive for SARS-CoV-2 and, after 30 days of mild-moderate respiratory symptoms, suddenly deteriorated and required extracorporeal membrane oxygenation. Lung biopsy was performed with findings consistent with organizing pneumonia. He received intensive therapy with high-dose methylprednisolone, intravenous immune globulin, rituximab, and plasmapheresis without improvement. He died after 85 days hospitalization. This case highlights unique presentations of COVID-19 and reaffirms the concept that, while rare in Hawai'i, pediatric COVID-19 is an ongoing problem and that severe, even fatal, disease can occur.

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一名患有 COVID-19 并发快速进展性严重组织性肺炎的儿童:病例报告。
一名两岁男孩的 SARS-CoV-2 检测呈阳性,在出现轻中度呼吸道症状 30 天后,病情突然恶化,需要进行体外膜氧合。对他进行了肺活检,结果与组织化肺炎一致。他接受了大剂量甲基强的松龙、静脉注射免疫球蛋白、利妥昔单抗和血浆置换等强化治疗,但病情未见好转。住院 85 天后死亡。本病例强调了COVID-19的独特表现形式,并再次证实了一个概念,即虽然小儿COVID-19在夏威夷很罕见,但仍是一个持续存在的问题,而且可能出现严重甚至致命的疾病。
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Addressing Physician Shortage in Hawai'i - Kaua'i Medical Training Opportunities. Alcohol-Induced & Drug-Induced Deaths in Hawai'i During the COVID-19 Pandemic. Building Resilience in Medical Students: "Strengthening You to Strengthen Them". A Child with COVID-19 Complicated by Rapidly Progressive Severe Organizing Pneumonia: A Case Report. Erratum in: A Rural Community Readiness Assessment of Prehospital Telestroke Services in the Ambulance.
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