Arginine vasopressin deficiency (central diabetes insipidus) with partial empty sella: a case report.

IF 2.8 3区 医学 Q3 ENDOCRINOLOGY & METABOLISM BMC Endocrine Disorders Pub Date : 2024-10-08 DOI:10.1186/s12902-024-01741-y
Kibret Enyew Belay, Rebil H Jemal, Ayele H Kebede, Meron G Tulu, Alamirew Enyew Belay, Asteway Mulat Haile, Samuel A Demisse
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Abstract

Background: Arginine vasopressin deficiency (central diabetes insipidus) is defined as a reduction in the release of arginine vasopressin (AVP) resulting in a variable degree of polyuria. Partial empty sella refers to an enlarged sella turcica that is not completely filled by pituitary gland. It can be either primary or secondary and its manifestation ranges from asymptomatic cases to isolated posterior pituitary, isolated anterior pituitary or both anterior and posterior pituitary dysfunctions. Diabetes insipidus caused by a partially empty sella is rare.

Case presentation: The patient, an 18-year-old Ethiopian woman who presented with long standing headache, increased urination, increased thirst, absence of menses and weight loss. Urine and serum osmolality was done and suggested diabetes insipidus. On further workup, brain magnetic resonant imaging was done and partially empty sella was diagnosed.

Conclusion: Diabetes insipidus secondary to partially empty sella is uncommon. In patients presenting with headache and anterior or posterior pituitary dysfunction, empty sella should be considered, whether partial or complete.

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精氨酸加压素缺乏症(中枢性糖尿病)伴部分蝶鞍空虚:病例报告。
背景:精氨酸加压素缺乏症(中枢性糖尿病)是指精氨酸加压素(AVP)释放减少,导致不同程度的多尿。部分空蝶鞍指的是脑垂体未完全充盈的肿大蝶鞍。它既可以是原发性的,也可以是继发性的,其表现范围从无症状病例到孤立的垂体后叶、孤立的垂体前叶或垂体前后叶功能障碍。因蝶鞍部分空虚而导致的糖尿病性尿崩症非常罕见:患者是一名 18 岁的埃塞俄比亚女性,因长期头痛、排尿增多、口渴、无月经和体重减轻而就诊。尿液和血清渗透压检查结果显示她患有糖尿病。进一步检查后,做了脑磁共振成像,诊断为部分空蝶鞍:结论:继发于部分脑脊膜空洞的糖尿病性尿崩症并不常见。结论:继发于部分脑蝶鞍空洞的糖尿病性血脂症并不常见,对于出现头痛、垂体前叶或后叶功能障碍的患者,应考虑脑蝶鞍部分或完全空洞。
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来源期刊
BMC Endocrine Disorders
BMC Endocrine Disorders ENDOCRINOLOGY & METABOLISM-
CiteScore
4.40
自引率
0.00%
发文量
280
审稿时长
>12 weeks
期刊介绍: BMC Endocrine Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of endocrine disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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