The clinical evolution of patients with idiopathic spinal cord herniation: a case series.

IF 0.7 Q4 CLINICAL NEUROLOGY Spinal Cord Series and Cases Pub Date : 2024-10-09 DOI:10.1038/s41394-024-00684-9
Stéphanie Flageol, Sylvine Carrondo-Cottin, André Turmel, Isabelle Côté, Jérôme Paquet
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Abstract

Study design: Retrospective case series of 48 patients.

Objectives: This study's primary objective was to provide a clinical description of a group of individuals with a working diagnosis of idiopathic spinal cord herniation (ISCH). The secondary objectives were to appreciate the natural history of these patients and describe their clinical evolution with conservative or surgical management.

Setting: The study was carried out at l'Hôpital de l'Enfant-Jésus, CHU de Québec (Québec, Canada), a tertiary care university hospital.

Methods: This case series study is based on routinely collected data. Forty-eight (48) cases were identified as having an ISCH on MR imaging, between 2009 and 2019. Their medical files have been searched retrospectively. Patient characteristics were described according to their asymptomatic or symptomatic status.

Results: The mean age of patients at the time of diagnosis was 52.5 years. Most of the patients identified were asymptomatic (69%) and followed clinically. The main neurologic presentation for the symptomatic group was Brown-Séquard-like syndrome. 20% of the symptomatic patients were rapidly treated surgically after consultation with the neurosurgeon. The mean follow-up duration was 56 months for asymptomatic patients and 51 months for symptomatic patients. Most of our patients (41 out of 45) were considered stable or unchanged at follow-up. There was no neurological progression in all asymptomatic patients.

Conclusions: Our study shows that ISCH and its variants are not always symptomatic and may be a fortuitous finding. As the natural history may be non-progressive, it is probably appropriate to treat some cases expectantly.

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特发性脊髓疝患者的临床演变:病例系列。
研究设计48例患者的回顾性病例系列:本研究的主要目的是对一组被诊断为特发性脊髓突出症(ISCH)的患者进行临床描述。次要目的是了解这些患者的自然病史,并描述他们在接受保守治疗或手术治疗后的临床演变情况:研究在魁北克大学儿童医院(CHU de Québec,加拿大魁北克省)l'Hôpital de l'Enfant-Jésus进行:本病例系列研究基于日常收集的数据。方法:本病例系列研究基于常规收集的数据。2009 年至 2019 年间,有 48 例病例在磁共振成像中被确定为患有 ISCH。对他们的医疗档案进行了回顾性检索。根据患者的无症状或有症状状态对其特征进行了描述:患者确诊时的平均年龄为 52.5 岁。大部分患者无症状(69%),并接受了临床随访。无症状组的主要神经系统表现为布朗-赛夸德样综合征。20%的无症状患者在与神经外科医生会诊后迅速接受了手术治疗。无症状患者的平均随访时间为56个月,有症状患者的平均随访时间为51个月。大多数患者(45 人中有 41 人)在随访时病情稳定或无变化。结论:我们的研究表明,ISCH 及其变异型并不总是有症状的,可能只是偶然发现。由于其自然病史可能是非进展性的,因此对某些病例进行预期治疗可能是合适的。
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来源期刊
Spinal Cord Series and Cases
Spinal Cord Series and Cases Medicine-Neurology (clinical)
CiteScore
2.20
自引率
8.30%
发文量
92
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