Effects of Head and Neck Cancer Radiotherapy on Cricothyroid Membrane Related Dimensions.

IF 0.6 Q4 SURGERY Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2024-10-01 Epub Date: 2024-06-28 DOI:10.1007/s12070-024-04855-w

Arun Muthukumar, Sekhar Khanpara, Robert C Wegner, Atin Goel, Mike Hernandez, Juan P Cata

{"title":"Effects of Head and Neck Cancer Radiotherapy on Cricothyroid Membrane Related Dimensions.","authors":"Arun Muthukumar, Sekhar Khanpara, Robert C Wegner, Atin Goel, Mike Hernandez, Juan P Cata","doi":"10.1007/s12070-024-04855-w","DOIUrl":null,"url":null,"abstract":"Background: Radiation treatment can modify soft tissue dynamics depending on the extent and location of irradiation. We hypothesized that head and neck radiotherapy caused alterations in cricothyroid membrane (CTM) related dimensions.Objectives: Primary objective was to evaluate changes in the cricothyroid membrane height (CTMH) and skin-to-CTM distance (STCD) in patients who underwent radiation treatment for head and neck cancers.Methods: Pre- and post-head-and-neck cancer-radiated computed tomography (CT) scans were analyzed retrospectively. The patients' demographics (age, sex, body mass index, cancer location), radiation dose and laterality, time from radiation initiation to CT scan assessments were summarized. CTMH and STCD were measured from pre-and post-radiation CT scans. Pre- and post-radiation comparisons were conducted using a paired t-test, or Wilcoxon signed-rank test if more appropriate. Chi-squared or Fisher's Exact test were used for categorical variables.Results: Among 231 study patients, who underwent head and neck radiotherapy in our institution 73.2% were males, and the median age of total population was 66 years (31-93). The median BMI was 25.2 kg/m2 (13.8-47.2). The median time from first radiation dose to CT scan assessment was 29.5 months (2-115).The median pre- and post-radiation CTMH were 8.7 mm (3-16.2) and 7.5 mm (3.1-14.3) respectively. The median pre- and post-radiation STCD were 11.7 mm (2.9-71.1) and 10.2 mm (3.9-38) respectively.Conclusion: In summary our patient population had significant reduction of cricothyroid membrane related dimensions following head-and-neck radiotherapy, which can limit the localization of the cricothyroid membrane.Level of evidence iii: Retrospective cohort study.","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":null,"pages":null},"PeriodicalIF":0.6000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11456054/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Otolaryngology and Head and Neck Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12070-024-04855-w","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/28 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"SURGERY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Radiation treatment can modify soft tissue dynamics depending on the extent and location of irradiation. We hypothesized that head and neck radiotherapy caused alterations in cricothyroid membrane (CTM) related dimensions.

Objectives: Primary objective was to evaluate changes in the cricothyroid membrane height (CTMH) and skin-to-CTM distance (STCD) in patients who underwent radiation treatment for head and neck cancers.

Methods: Pre- and post-head-and-neck cancer-radiated computed tomography (CT) scans were analyzed retrospectively. The patients' demographics (age, sex, body mass index, cancer location), radiation dose and laterality, time from radiation initiation to CT scan assessments were summarized. CTMH and STCD were measured from pre-and post-radiation CT scans. Pre- and post-radiation comparisons were conducted using a paired t-test, or Wilcoxon signed-rank test if more appropriate. Chi-squared or Fisher's Exact test were used for categorical variables.

Results: Among 231 study patients, who underwent head and neck radiotherapy in our institution 73.2% were males, and the median age of total population was 66 years (31-93). The median BMI was 25.2 kg/m² (13.8-47.2). The median time from first radiation dose to CT scan assessment was 29.5 months (2-115).The median pre- and post-radiation CTMH were 8.7 mm (3-16.2) and 7.5 mm (3.1-14.3) respectively. The median pre- and post-radiation STCD were 11.7 mm (2.9-71.1) and 10.2 mm (3.9-38) respectively.

Conclusion: In summary our patient population had significant reduction of cricothyroid membrane related dimensions following head-and-neck radiotherapy, which can limit the localization of the cricothyroid membrane.

Level of evidence iii: Retrospective cohort study.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

头颈癌放疗对环甲膜相关尺寸的影响

背景：放射治疗可改变软组织动力学，这取决于照射的范围和位置。我们假设头颈部放疗会引起环甲膜（CTM）相关尺寸的改变：主要目的是评估头颈部癌症放疗患者环甲膜高度（CTMH）和皮肤到环甲膜距离（STCD）的变化：方法：对头颈部癌症放射治疗前后的计算机断层扫描（CT）进行回顾性分析。总结了患者的人口统计学特征（年龄、性别、体重指数、癌症位置）、放射剂量和侧位、从放射开始到 CT 扫描评估的时间。CTMH 和 STCD 是根据放射前后的 CT 扫描结果测量的。辐射前和辐射后的比较采用配对 t 检验或 Wilcoxon 符号秩检验（如果更合适）。对分类变量采用卡方检验或费雪精确检验：在我院接受头颈部放疗的 231 名患者中，73.2% 为男性，总人数的中位年龄为 66 岁（31-93 岁）。体重指数中位数为 25.2 kg/m2 (13.8-47.2)。从首次接受放射剂量到进行CT扫描评估的中位时间为29.5个月（2-115）。放射治疗前后的中位CTMH分别为8.7毫米（3-16.2）和7.5毫米（3.1-14.3）。放疗前后的 STCD 中位数分别为 11.7 毫米（2.9-71.1）和 10.2 毫米（3.9-38）：总之，我们的患者在接受头颈部放疗后，环甲膜相关尺寸明显缩小，这可能会限制环甲膜的定位：回顾性队列研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Indian Journal of Otolaryngology and Head and Neck Surgery Medicine-Otorhinolaryngology

CiteScore

0.80

自引率

0.00%

发文量

226

审稿时长

6-12 weeks

期刊介绍： Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.