Sparse-View Photoacoustic Reconstruction Method for Diabetic Retinopathy Using Feature Fusion Network.

Abstract

Diabetic retinopathy is one of the most prevalent microvascular complications of diabetes mellitus, and photoacoustic imaging is an effective method for imaging diabetic retinal vessels. Photoacoustic imaging is an emerging noninvasive imaging method based on the photoacoustic effect, which offers advantages of contrast, resolution, and depth imaging. Appropriate photoacoustic reconstruction methods are essential for obtaining high-quality photoacoustic images. In this study, a multi-input self-attention multiscale feature fusion network (SAMF-Net) is proposed for photoacoustic reconstruction. The algorithm accepts two inputs, namely the original photoacoustic signal and the traditional reconstructed image. Furthermore, a global feature extraction module based on the self-attention mechanism is employed to focus on the global information. The results demonstrate that the proposed method exhibits superior reconstruction capability under different sparse detection views. The method has instructive value for photoacoustic image reconstruction and has the potential for further application in the diagnosis of diabetic retinopathy.