Overall congenital defect risk unchanged by antidepressant/benzo use

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Abstract

A population-based cohort study has found that concomitant use of antidepressants and benzodiazepines in the first trimester of pregnancy did not substantially increase risk overall for congenital malformations. Digestive system malformations were the only defects for which a significant risk remained in adjusted analyses. Study results were published online July 2, 2024, in Lancet Psychiatry.

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使用抗抑郁剂/苯并类药物的总体先天缺陷风险不变
一项基于人群的队列研究发现,在怀孕头三个月同时服用抗抑郁药和苯并二氮杂卓类药物并不会大幅增加先天性畸形的总体风险。在调整分析中,消化系统畸形是唯一仍有显著风险的缺陷。研究结果于2024年7月2日在线发表在《柳叶刀精神病学》上。
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