{"title":"A facile, catalyst- and additive-free, and scalable approach to the photochemical preparation of disulfides from organosulfenyl chlorides†","authors":"Wei Liu, Jiayi Wang and Gonghua Song","doi":"10.1039/D4RA04568H","DOIUrl":null,"url":null,"abstract":"<p >A novel, clean and efficient protocol for the preparation of disulfides has been developed through the photochemical radical homo- and cross-coupling reaction of sulfenyl chlorides under LED irradiation and without the use of any catalyst and additive. The representative photochemical homo-coupling of trichloromethyl sulfenyl chloride has been successfully conducted on kilogram-scale in a continuous flow mode. The solvent and the main byproduct can be recovered in high yields, which makes the approach be highly atom economical.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":null,"pages":null},"PeriodicalIF":3.9000,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/ra/d4ra04568h?page=search","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"RSC Advances","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2024/ra/d4ra04568h","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A novel, clean and efficient protocol for the preparation of disulfides has been developed through the photochemical radical homo- and cross-coupling reaction of sulfenyl chlorides under LED irradiation and without the use of any catalyst and additive. The representative photochemical homo-coupling of trichloromethyl sulfenyl chloride has been successfully conducted on kilogram-scale in a continuous flow mode. The solvent and the main byproduct can be recovered in high yields, which makes the approach be highly atom economical.
期刊介绍:
An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.