Association between blood lead levels and socio-demographic factors among outpatient children in Ningbo, China

IF 0.8 4区 工程技术 Q4 CHEMISTRY, ANALYTICAL Accreditation and Quality Assurance Pub Date : 2024-06-24 DOI:10.1007/s00769-024-01609-7
Chengbo Zhou, Wenbo Lu, Haiyan Qiu, Lihua Zhu, Jishan Zheng, Wenyuan Liu
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Abstract

Lead exposure is a well-known health concern, affecting children worldwide. We aim to assess children’s blood lead levels (BLLs), and the association of risk factors with elevated BLL in children since the phase-out of leaded gasoline. We enrolled 8085 outpatient children to assess their blood lead levels, and the associations with social-demographic factors. Social-demographic information was obtained by using questionnaires. Multivariable linear and logistic regression models were performed to explore the associations between social-demographic factors and elevated BLLs. The geometric mean BLL was 15.96 μg/L. The prevalence rates of elevated BLLs (≧ 100 μg/L and ≧ 50 μg/L) were 2.0 % and 10.9 %, respectively. BLLs in boys were higher than that in girls (P < 0.001). Girls had a lower risk of BLLs above 50 μg/L than boys (OR = 0.83, 95 % CI 0.71–0.96). Father’s occupation as a skilled laborer or professional worker and living in the suburbs significantly contributed to the elevated BLLs ( ≧ 50 μg/L), with the ORs of 1.39 (1.06–1.81), 1.33 (1.01–1.75) and 1.24 (1.02–1.50), respectively. Our results suggested that children who lived in suburbs and whose fathers were skilled laborers and professional workers were more likely to have BLLs above 50 μg/L.

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中国宁波门诊儿童血铅水平与社会人口因素的关系
铅暴露是众所周知的健康问题,影响着全世界的儿童。我们的目的是评估儿童的血铅含量(BLLs),以及自含铅汽油逐步淘汰以来儿童血铅含量升高与风险因素的关联。我们招募了 8085 名门诊儿童,以评估他们的血铅水平以及与社会人口因素的关联。社会人口学信息通过问卷调查获得。我们采用多变量线性回归和逻辑回归模型来探讨社会人口因素与血铅含量升高之间的关系。几何平均 BLL 为 15.96 微克/升。BLL 升高(≧ 100 μg/L 和 ≧ 50 μg/L)的发生率分别为 2.0 % 和 10.9 %。男孩的 BLL 值高于女孩(P < 0.001)。女孩的 BLL 超过 50 μg/L 的风险低于男孩(OR = 0.83,95 % CI 0.71-0.96)。父亲的职业是技术工人或专业工人以及居住在郊区也是导致儿童血清白蛋白升高(≧ 50 μg/L)的重要原因,OR 值分别为 1.39(1.06-1.81)、1.33(1.01-1.75)和 1.24(1.02-1.50)。我们的研究结果表明,居住在郊区、父亲是技术工人和专业工人的儿童,其血清胆固醇水平超过 50 μg/L 的可能性更大。
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来源期刊
Accreditation and Quality Assurance
Accreditation and Quality Assurance 工程技术-分析化学
CiteScore
1.80
自引率
22.20%
发文量
39
审稿时长
6-12 weeks
期刊介绍: Accreditation and Quality Assurance has established itself as the leading information and discussion forum for all aspects relevant to quality, transparency and reliability of measurement results in chemical and biological sciences. The journal serves the information needs of researchers, practitioners and decision makers dealing with quality assurance and quality management, including the development and application of metrological principles and concepts such as traceability or measurement uncertainty in the following fields: environment, nutrition, consumer protection, geology, metallurgy, pharmacy, forensics, clinical chemistry and laboratory medicine, and microbiology.
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